- Combining beta interferon and atorvastatin may increase disease activity in multiple sclerosis
[作者:Birnbaum, G; Cree, B; Altafullah, I; Zinser, M; Reder, AT,期刊:Neurology, 页码:1390-1395 , 文章类型: Article,,卷期:2008年71-18]
- Objective: To explore whether high-dose atorvastatin can be administered safely to persons with relapsing-remitting multiple sclerosis (MS) taking thrice weekly, 44 mu g dose subcutaneous interferon beta-1a.Methods: Pers...
- Impaired action knowledge in amyotrophic lateral sclerosis
[作者:Grossman, M; Anderson, C; Khan, A; Avants, B; Elman, L; McCluskey, L,期刊:Neurology, 页码:1396-1401 , 文章类型: Article,,卷期:2008年71-18]
- Background: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative condition affecting the motor system, but recent work also shows more widespread cognitive impairment. This study examined performance on measures re...
- The HAT Score A simple grading scale for predicting hemorrhage after thrombolysis
[作者:Lou, M; Safdar, A; Mehdiratta, M; Kumar, S; Schlaug, G; Caplan, L; Searls, D; Selim, M,期刊:Neurology, 页码:1417-1423 , 文章类型: Article,,卷期:2008年71-18]
- Objective: To develop a grading scale to predict the risk of intracerebral hemorrhage (ICH) and prognosis after treatment with IV tissue-plasminogen activator (t-PA) in patients with ischemic stroke.Methods: We construct...
- Unilateral neglect is more severe and common in older patients with right hemispheric stroke
[作者:Gottesman, RF; Kleinman, JT; Davis, C; Heidler-Gary, J; Newhart, M; Kannan, V; Hillis, AE,期刊:Neurology, 页码:1439-1444 , 文章类型: Article,,卷期:2008年71-18]
- Introduction: Unilateral neglect after acute right hemispheric stroke significantly impedes post-stroke recovery. We studied patients with right hemispheric stroke to determine whether increasing age was associated with ...
- Neurodegeneration associated with genetic defects in phospholipase A(2)
[作者:Gregory, A; Westaway, SK; Holm, IE; Kotzbauer, PT; Hogarth, P; Sonek, S; Coryell, JC; Nguyen, TM; Nardocci, N; Zorzi, G; Rodriguez, D; Desguerre, I; Bertini, E; Simonati, A; Levinson, B; Dias, C; Barbot, C; Carrilho, I; Santos, M; Malik, I; Gitschier, J; Hayflick, SJ,期刊:Neurology, 页码:1402-1409 , 文章类型: Article,,卷期:2008年71-18]
- Objective: Mutations in the gene encoding phospholipase A 2 group VI (PLA2G6) are associated with two childhood neurologic disorders: infantile neuroaxonal dystrophy (INAD) and idiopathic neurodegeneration with brain iro...
- Impaired visual evoked flow velocity response in cerebral amyloid angiopathy
[作者:Smith, EE; Vijayappa, M; Lima, F; Delgado, P; Wendell, L; Rosand, J; Greenberg, SM,期刊:Neurology, 页码:1424-1430 , 文章类型: Article,,卷期:2008年71-18]
- Objective: Animal models of cerebral amyloid angiopathy (CAA) exhibit abnormal vascular reactivity. We determined whether vascular reactivity, measured by transcranial Doppler ultrasound (TCD), is reduced in humans with ...
- Tracking progression in frontotemporal lobar degeneration Serial MRI in semantic dementia
[作者:Rohrer, JD; McNaught, E; Foster, J; Clegg, SL; Barnes, J; Omar, R; Warrington, EK; Rossor, MN; Warren, JD; Fox, NC,期刊:Neurology, 页码:1445-1451 , 文章类型: Article,,卷期:2008年71-18]
- Background: Semantic dementia is a sporadic neurodegenerative disorder characterized by the progressive erosion of semantic processing and is one of the canonical subtypes of frontotemporal lobar degeneration. This study...
- The Gilles de la Tourette Syndrome-Quality of Life Scale (GTS-QOL) Development and validation
[作者:Cavanna, AE; Schrag, A; Morley, D; Orth, M; Robertson, MM; Joyce, E; Critchley, HD; Selai, C,期刊:Neurology, 页码:1410-1416 , 文章类型: Article,,卷期:2008年71-18]
- Background: Gilles de la Tourette syndrome (GTS) is a chronic neuropsychiatric disorder which has a significant detrimental impact on the health-related quality of life (HR-QOL) of patients. However, no patient-reported ...
- A novel PRNP-P105S mutation associated with atypical prion disease and a rare PrPSc conformation
[作者:Tunnell, E; Wollman, R; Mallik, S; Cortes, CJ; DeArmond, SJ; Mastrianni, JA,期刊:Neurology, 页码:1431-1438 , 文章类型: Article,,卷期:2008年71-18]
- Objective: To define the clinicopathologic, genetic, and pathogenic prion protein (PrPSc) characteristics associated with a novel mutation of the prion protein gene (PRNP).Methods: The coding segment of PRNP from the pro...
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