- Determinants of the distribution and severity of hypoperfusion in patients with ischemic stroke
[作者：Bang, OY; Saver, JL; Alger, JR; Starkman, S; Ovbiagele, B; Liebeskind, DS,期刊：Neurology, 页码：1804-1811 , 文章类型： Article，,卷期：2008年71-22]
- Background: In acute cerebral ischemia, two variables characterize the extent of hypoperfusion: the volume of hypoperfused tissue and the intensity of hypoperfusion within these regions. We evaluated the determinants of ...
- Novel congenital myopathy locus identified in Native American Indians at 12q13.13-14.1
[作者：Stamm, DS; Powell, CM; Stajich, JM; Zismann, VL; Stephan, DA; Chesnut, B; Aylsworth, AS; Kahler, SG; Deak, KL; Gilbert, JR; Speer, MC,期刊：Neurology, 页码：1764-1769 , 文章类型： Article，,卷期：2008年71-22]
- Background: Native American myopathy (NAM) is an autosomal recessive congenital myopathy first reported in the Lumbee Indian people. Features of NAM include congenital weakness, cleft palate, ptosis, short stature, and s...
- Subcutaneous IGF-1 is not beneficial in 2-year ALS trial
[作者：Sorenson, EJ; Windbank, AJ; Mandrekar, JN; Bamlet, WR; Appel, SH; Armon, C; Barkhaus, PE; Bosch, P; Boylan, K; David, WS; Feldman, E; Glass, J; Gutmann, L; Katz, J; King, W; Luciano, CA; McCluskey, LF; Nash, S; Newman, DS; Pascuzzi, RM; Pioro, E; Sams, LJ; Scelsa, S; Simpson, EP; Subramony, SH; Tiryaki, E; Thornton, CA,期刊：Neurology, 页码：1770-1775 , 文章类型： Article，,卷期：2008年71-22]
- Background: Previous human clinical trials of insulin-like growth factor type I (IGF-1) in amyotrophic lateral sclerosis (ALS) have been inconsistent. This phase III, randomized, double-blind, placebo-controlled study wa...
- Gentamicin vestibulotoxicity impairs human electrically evoked vestibulo-ocular reflex
[作者：Aw, ST; Todd, MJ; Aw, GE; Weber, KP; Halmagyi, GM,期刊：Neurology, 页码：1776-1782 , 文章类型： Article，,卷期：2008年71-22]
- Background: Electrical vestibular stimulation is believed to directly activate the vestibular afferents to mediate an electrically evoked vestibulo-ocular reflex (eVOR). Gentamicin, an aminoglycoside antibiotic, induces ...
- Progression of dopaminergic dysfunction in a LRRK2 kindred A multitracer PET study
[作者：Nandhagopal, R; Mak, E; Schulzer, M; McKenzie, J; McCormick, S; Sossi, V; Ruth, TJ; Strongosky, A; Farrer, MJ; Wszolek, ZK; Stoessl, AJ,期刊：Neurology, 页码：1790-1795 , 文章类型： Article，,卷期：2008年71-22]
- Objective: Little is known about the progression of dopaminergic dysfunction in LRRK2-associated Parkinson disease (PD). We sought to characterize the neurochemical progression with multitracer PET in asymptomatic member...
- Tau forms in CSF as a reliable biomarker for progressive supranuclear palsy
[作者：Borroni, B; Malinverno, M; Gardoni, F; Alberici, A; Parnetti, L; Premi, E; Bonuccelli, U; Grassi, M; Perani, D; Calabresi, P; Di Luca, M; Padovani, A,期刊：Neurology, 页码：1796-1803 , 文章类型： Article，,卷期：2008年71-22]
- Objective: In CSF, extended (55 kDa) and truncated (33 kDa) tau forms have been previously recognized, and the tau 33 kDa/55 kDa ratio has been found significantly reduced in progressive supranuclear palsy (PSP) vs in ot...
- Multiple sclerosis and the TNFRSF1A R92Q mutation Clinical characteristics of 21 cases
[作者：Kumpfel, T; Hoffmann, LA; Pellkofer, H; Pollmann, W; Feneberg, W; Hohlfeld, R; Lohse, P,期刊：Neurology, 页码：1812-1820 , 文章类型： Article，,卷期：2008年71-22]
- Objective: Tumor necrosis factor receptor 1-associated periodic syndrome (TRAPS) is an autosomal dominantly inherited autoinflammatory disorder resulting from mutations in the TNFRSF1A gene, which encodes the p55 recepto...
- A two-site ELISA can quantify upregulation of SMN protein by drugs for spinal muscular atrophy
[作者：Man, NT; Humphrey, E; Lam, LT; Fuller, HR; Lynch, TA; Sewry, CA; Goodwin, PR; MacKenzie, AE; Morris, GE,期刊：Neurology, 页码：1757-1763 , 文章类型： Article，,卷期：2008年71-22]
- Objectives: Spinal muscular atrophy (SMA) is an autosomal recessive disorder characterized by loss of lower motor neurons during early or postnatal development. Severity is variable and is inversely related to the levels...
- Excessive acute migraine medication use and migraine progression
[作者：Bigal, ME; Lipton, RB,期刊：Neurology, 页码：1821-1828 , 文章类型： Review，,卷期：2008年71-22]
- Long considered a chronic disorder with a stable course, recent research demonstrates that, in a subgroup, migraine progresses to chronic migraine. Among the risk factors for migraine progression, acute symptomatic medic...
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