- Partial A(1) Adenosine Receptor Agonist Regulates Cardiac Substrate Utilization in Insulin-Resistant Rats in Vivo
[作者:Shearer, J; Severson, DL; Su, L; Belardinelli, L; Dhalla, AK,期刊:Journal of Pharmacology and Experimental Therapeutics, 页码:306-311 , 文章类型: Article,,卷期:2009年328-1]
Reducing the availability and uptake of fatty acids is a plausible pharmaceutical target to ameliorate glucose intolerance and insulin resistance. CVT-3619 [2-{6-[((1R,2R)-2-hydroxycyclopentyl) amino]purin-9-yl(4S,5S,...
- Opposite Effects of Two Resveratrol (trans-3,5,4 ' Trihydroxystilbene) Tetramers, Vitisin A and Hopeaphenol, on Apoptosis of Myocytes Isolated from Adult Rat Heart
[作者:Seya, K; Kanemaru, K; Sugimoto, C; Suzuki, M; Takeo, T; Motomura, S; Kitahara, H; Niwa, M; Oshima, Y; Furukawa, KI,期刊:Journal of Pharmacology and Experimental Therapeutics, 页码:90-98 , 文章类型: Article,,卷期:2009年328-1]
It has been reported that resveratrol (trans-3,5,4 '-trihydroxystilbene) from Vitis plants has various cardioprotective effects. Vitis plants also include various resveratrol tetramers. The aim of our study is to clar...
- The Role of ATP Binding Cassette Transporters in Tissue Defense and Organ Regeneration
[作者:Huls, M; Russel, FGM; Masereeuw, R,期刊:Journal of Pharmacology and Experimental Therapeutics, 页码:3-9 , 文章类型: Review,,卷期:2009年328-1]
ATP binding cassette (ABC) transporters are ATP-dependent membrane proteins predominantly expressed in excretory organs, such as the liver, intestine, blood-brain barrier, blood-testes barrier, placenta, and kidney. H...
- Differential Effects of Diet-Induced Dyslipidemia and Hyperglycemia on Mesenteric Resistance Artery Structure and Function in Type 2 Diabetes
[作者:Sachidanandam, K; Hutchinson, JR; Elgebaly, MM; Mezzetti, EM; Wang, MH; Ergul, A,期刊:Journal of Pharmacology and Experimental Therapeutics, 页码:123-130 , 文章类型: Article,,卷期:2009年328-1]
Type 2 diabetes and dyslipidemia oftentimes present in combination. However, the relative roles of diabetes and diet-induced dyslipidemia in mediating changes in vascular structure, mechanics, and function are poorly ...
- Therapeutic Effect of Lecithinized Superoxide Dismutase against Colitis
[作者:Ishihara, T; Tanaka, KI; Tasaka, Y; Namba, T; Suzuki, J; Ishihara, T; Okamoto, S; Hibi, T; Takenaga, M; Igarashi, R; Sato, K; Mizushima, Y; Mizushima, T,期刊:Journal of Pharmacology and Experimental Therapeutics, 页码:152-164 , 文章类型: Article,,卷期:2009年328-1]
Ulcerative colitis (UC) involves intestinal mucosal damage induced by reactive oxygen species (ROS), in particular, superoxide anion. Superoxide dismutase (SOD) catalyzes dismutation of superoxide anion to hydrogen pe...
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