- Aberrant Heparan Sulfate Proteoglycan Localization, Despite Normal Exostosin, in Central Chondrosarcoma
[作者：Schrage, YM; Hameetman, L; Szuhai, K; Cleton-Jansen, AM; Taminiau, AHM; Hogendoorn, PCW; Bovee, JVMG,期刊：American Journal of Pathology, 页码：979-988 , 文章类型： Article，,卷期：2009年174-3]
- The tumor suppressor genes EXT1 and EXT2 are involved in the formation of multiple osteochondromas, which can progress to become secondary peripheral chondrosarcomas. The most common chondrosarcoma subtype is primary cen...
- Role of Regulatory T Cells in a New Mouse Model of Experimental Autoimmune Myositis
[作者：Allenbach, Y; Solly, S; Greegoire, S; Dubourg, O; Salomon, B; Butler-Browne, G; Musset, L; Herson, S; Klatzmann, D; Benveniste, O,期刊：American Journal of Pathology, 页码：989-998 , 文章类型： Article，,卷期：2009年174-3]
- Polymyositis is a rare and severe inflammatory muscle disorder. Treatments are partially efficacious but have many side effects. New therapeutic approaches must be first tested in a relevant animal model. Regulatory CD4+...
- Ribozyme-Mediated Targeting of I kappa B gamma Inhibits Melanoma Invasion and Metastasis
[作者：Torabian, SZ; de Semir, D; Nosrati, M; Bagheri, S; Dar, AA; Fong, S; Liu, Y; Federman, S; Simko, J; Haqq, C; Debs, RJ; Kashani-Sabet, M,期刊：American Journal of Pathology, 页码：1009-1016 , 文章类型： Article，,卷期：2009年174-3]
- I kappa B gamma Is one member of a family of proteins that can inhibit the nuclear localization of nuclear factor-kappa B. However, the other specific functions of I kappa B gamma are still poorly understood, and its eff...
- Ezetimibe Is an Inhibitor of Tumor Angiogenesis
[作者：Solomon, KR; Pelton, K; Boucher, K; Joo, J; Tully, C; Zurakowski, D; Schaffner, CP; Kim, J; Freeman, MR,期刊：American Journal of Pathology, 页码：1017-1026 , 文章类型： Article，,卷期：2009年174-3]
- Epidemiological and preclinical. observations have suggested a role for one or more products, of the mevalonate/cholesterol biosynthesis pathway in the progression of prostate cancer. In this study, we used ezetimibe (Ze...
- Spontaneous Metastasis of Prostate Cancer Is Promoted by Excess Hyaluronan Synthesis and Processing
[作者：Bharadwaj, AG; Kovar, JL; Loughman, E; Elowsky, C; Oakley, GG; Simpson, MA,期刊：American Journal of Pathology, 页码：1027-1036 , 文章类型： Article，,卷期：2009年174-3]
- Accumulation of extracellular hyaluronan (HA) and its processing enzyme, the hyaluronidase Hyal1, predicts invasive, metastatic progression of human prostate cancer. To dissect the roles of hyaluronan synthases (HAS) and...
- Proepithelin Regulates Prostate Cancer Cell Biology by Promoting Cell Growth, Migration, and Anchorage-Independent Growth
[作者：Monami, G; Emiliozzi, V; Bitto, A; Lovat, F; Xu, SQ; Goldoni, S; Fassan, M; Serrero, G; Gomella, LG; Baffa, R; Iozzo, RV; Morrione, A,期刊：American Journal of Pathology, 页码：1037-1047 , 文章类型： Article，,卷期：2009年174-3]
- The growth factor proepithelin has recently emerged as an important regulator of transformation in several physiological and pathological systems. In this study, we determined the biological roles of proepithelin in pros...
- High-Density Gene Expression Analysis of Tumor-Associated Macrophages from Mouse Mammary Tumors
[作者：Ojalvo, LS; King, W; Cox, D; Pollard, JW,期刊：American Journal of Pathology, 页码：1048-1064 , 文章类型： Article，,卷期：2009年174-3]
- Clinical and experimental evidence indicates that tumor-associated macrophages (TAMs) promote malignant progression. in breast cancer, TAMs enhance tumor angiogenesis, tumor cell invasion, matrix remodeling, and immune s...
- Fetal Liver Cells Transplanted in Utero Rescue the Osteopetrotic Phenotype in the oc/oc Mouse
[作者：Tondelli, B; Blair, HC; Guerrini, M; Patrene, KD; Cassani, B; Vezzoni, P; Lucchini, F,期刊：American Journal of Pathology, 页码：727-735 , 文章类型： Article，,卷期：2009年174-3]
- Autosomal recessive osteopetrosis (ARO) is a group of genetic disorders that involve defects that preclude the normal function of osteoclasts, which differentiate from hematopoietic precursors. In half of human cases, AR...
- Low-Level Expression of MicroRNAs let-7d and miR-205 Are Prognostic Markers of Head and Neck Squamous Cell Carcinoma
[作者：Childs, G; Fazzari, M; Kung, G; Kawachi, N; Brandwein-Gensler, M; McLemore, M; Chen, Q; Burk, RD; Smith, RV; Prystowsky, MB; Belbin, TJ; Schlecht, NF,期刊：American Journal of Pathology, 页码：736-745 , 文章类型： Article，,卷期：2009年174-3]
- Small noncoding microRNAs (miRNAs) have been shown to be abnormally expressed in every tumor type examined. The importance of miRNAs as potential cancer prognostic indicators is underscored by their involvement in the re...
- Caveolin-1(-/-) Null Mammary Stromal Fibroblasts Share Characteristics with Human Breast Cancer-Associated Fibroblasts
[作者：Sotgia, F; Del Galdo, F; Casimiro, MC; Bonuccelli, G; Mercier, I; Whitaker-Menezes, D; Daumer, KM; Zhou, J; Wang, CG; Katiyar, S; Xu, H; Bosco, E; Quong, AA; Aronow, B; Witkiewicz, AK; Minetti, C; Frank, PG; Jimenez, SA; Knudsen, ES; Pestell, RG; Lisanti, MP,期刊：American Journal of Pathology, 页码：746-761 , 文章类型： Article，,卷期：2009年174-3]
- Recently, we reported that human breast cancer-associated fibroblasts show functional inactivation of the retinoblastoma (RB) tumor suppressor and down-regulation of caveolin-1 (Cav-1) protein expression. However, it rem...
- Identification of Potential Therapeutic Targets in Malignant Mesothelioma Using Cell-Cycle Gene Expression Analysis
[作者：Romagnoli, S; Fasoli, E; Vaira, V; Falleni, M; Pellegrini, C; Catania, A; Roncalli, M; Marchetti, A; Santambrogio, L; Coggi, G; Bosari, S,期刊：American Journal of Pathology, 页码：762-770 , 文章类型： Article，,卷期：2009年174-3]
- Cell-cycle defects are responsible for cancer onset and growth. We studied the expression profile of 60 genes involved in cell cycle in a series of malignant mesotheliomas (MMs), normal pleural tissues, and MM cell cultu...
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