- Development of Human Nervous Tissue upon Differentiation of Embryonic Stem Cells in Three-Dimensional Culture
[作者:Preynat-Seauve, O; Suter, DM; Tirefort, D; Turchi, L; Virolle, T; Chneiweiss, H; Foti, M; Lobrinus, JA; Stoppini, L; Feki, A; Dubois-Dauphin, M; Krause, KH,期刊:Stem Cells, 页码:509-520 , 文章类型: Article,,卷期:2009年27-3]
- Researches on neural differentiation using embryonic stem cells (ESC) require analysis of neurogenesis in conditions mimicking physiological cellular interactions as closely as possible. In this study, we report an air-l...
- BAC Transgenesis in Human Embryonic Stem Cells as a Novel Tool to Define the Human Neural Lineage
[作者:Placantonakis, DG; Tomishima, MJ; Lafaille, F; Desbordes, SC; Jia, F; Socci, ND; Viale, A; Lee, H; Harrison, N; Tabar, V; Studer, L,期刊:Stem Cells, 页码:521-532 , 文章类型: Article,,卷期:2009年27-3]
- Human embryonic stem cells (hESCs) have enormous potential for applications in basic biology and regenerative medicine. However, harnessing the potential of hESCs toward generating homogeneous populations of specialized ...
- Induced Pluripotent Stem Cell Generation Using a Single Lentiviral Stem Cell Cassette
[作者:Sommer, CA; Stadtfeld, M; Murphy, GJ; Hochedlinger, K; Kotton, DN; Mostoslavsky, G,期刊:Stem Cells, 页码:543-549 , 文章类型: Article,,卷期:2009年27-3]
- Induced pluripotent stem (iPS) cells can be generated using retroviral vectors expressing Oct4, Klf4, Sox2, and cMyc. Most prior studies have required multiple retroviral vectors for reprogramming, resulting in high numb...
- Autocrine Regulation of Interferon gamma in Mesenchymal Stem Cells Plays a Role in Early Osteoblastogenesis
[作者:Duque, G; Huang, DC; Macoritto, M; Rivas, D; Yang, XF; Ste-Marie, LG; Kremer, R,期刊:Stem Cells, 页码:550-558 , 文章类型: Article,,卷期:2009年27-3]
- Interferon (IFN)gamma is a strong inhibitor of osteoclast differentiation and activity. However, its role in osteoblastogenesis has not been carefully examined. Using microarray expression analysis, we found that several...
- Hematopoietic and Endothelial Differentiation of Human Induced Pluripotent Stem Cells
[作者:Choi, KD; Yu, J; Smuga-Otto, K; Salvagiotto, G; Rehrauer, W; Vodyanik, M; Thomson, J; Slukvin, I,期刊:Stem Cells, 页码:559-567 , 文章类型: Article,,卷期:2009年27-3]
- Induced pluripotent stem cells (iPSCs) provide an unprecedented opportunity for modeling of human diseases in vitro, as well as for developing novel approaches for regenerative therapy based on immunologically compatible...
- DNA Damage Mediated S and G(2) Checkpoints in Human Embryonal Carcinoma Cells
[作者:Wang, XQ; Lui, VCH; Poon, RTP; Lu, P; Poon, RYC,期刊:Stem Cells, 页码:568-576 , 文章类型: Article,,卷期:2009年27-3]
- For mouse embryonic stem (ES) cells, the importance of the S and G(2) cell cycle checkpoints for genomic integrity is increased by the absence of the G(1) checkpoint. We have investigated ionizing radiation (IR)-mediated...
- The Adhesion Molecule Esam1 Is a Novel Hematopoietic Stem Cell Marker
[作者:Ooi, AGL; Karsunky, H; Majeti, R; Butz, S; Vestweber, D; Ishida, T; Quertermous, T; Weissman, IL; Forsberg, EC,期刊:Stem Cells, 页码:653-661 , 文章类型: Article,,卷期:2009年27-3]
- Hematopoietic stem cells (HSCs) have been highly enriched using combinations of 12-14 surface markers. Genes specifically expressed by HSCs as compared with other multipotent progenitors may yield new stem cell enrichmen...
- Spherically Symmetric Mesenchymal Stromal Cell Bodies Inherent with Endogenous Extracellular Matrices for Cellular Cardiomyoplasty
[作者:Wang, CC; Chen, CH; Hwang, SM; Lin, WW; Huang, CH; Lee, WY; Chang, Y; Sung, HW,期刊:Stem Cells, 页码:724-732 , 文章类型: Article,,卷期:2009年27-3]
- Cell transplantation via direct intramyocardial injection is a promising therapy for patients with myocardial infarction; however, retention of the transplanted cells at the injection sites remains a central issue follow...
- Prospective Isolation of Bronchiolar Stem Cells Based Upon Immunophenotypic and Autofluorescence Characteristics
[作者:Teisanu, RM; Lagasse, E; Whitesides, JF; Stripp, BR,期刊:Stem Cells, 页码:612-622 , 文章类型: Article,,卷期:2009年27-3]
- Bronchiolar stem cells have been functionally defined in vivo on the basis of their resistance to chemical (naphthalene) injury, their infrequent proliferation relative to other progenitor cell types, and their coexpress...
- Multipotent Stromal Cells Are Activated to Reduce Apoptosis in Part by Upregulation and Secretion of Stanniocalcin-1
[作者:Block, GJ; Ohkouchi, S; Fung, F; Frenkel, J; Gregory, C; Pochampally, R; DiMattia, G; Sullivan, DE; Prockop, DJ,期刊:Stem Cells, 页码:670-681 , 文章类型: Article,,卷期:2009年27-3]
- Multipotent stromal cells (MSCs) have been shown to reduce apoptosis in injured cells by secretion of paracrine factors, but these factors were not fully defined. We observed that coculture of MSCs with previously UV-irr...
- Lineage-Negative Bone Marrow Cells Protect Against Chronic Renal Failure
[作者:Alexandre, CS; Volpini, RA; Shimizu, MH; Sanches, TR; Semedo, P; Di Jura, VL; Camara, NO; Seguro, AC; Andrade, L,期刊:Stem Cells, 页码:682-692 , 文章类型: Article,,卷期:2009年27-3]
- Progressive renal failure continues to be a challenge. The use of bone marrow cells represents a means of meeting that challenge. We used lineage-negative (Lin(-)) cells to test the hypothesis that Lin(-) cell treatment ...
- Endogenous Fibroblastic Progenitor Cells in the Adult Mouse Lung Are Highly Enriched in the Sca-1 Positive Cell Fraction
[作者:McQualter, JL; Brouard, N; Williams, B; Baird, BN; Sims-Lucas, S; Yuen, K; Nilsson, SK; Simmons, PJ; Bertoncello, I,期刊:Stem Cells, 页码:623-633 , 文章类型: Article,,卷期:2009年27-3]
- Originally identified as a marker specifying murine hematopoietic stem cells, the Sca-1 antigen has since been shown to be differentially expressed by candidate stem cells in tissues including vascular endothelium, skele...
- Activation of Hedgehog Signaling Inhibits Osteoblast Differentiation of Human Mesenchymal Stem Cells
[作者:Plaisant, M; Fontaine, C; Cousin, W; Rochet, N; Dani, C; Peraldi, P,期刊:Stem Cells, 页码:703-713 , 文章类型: Article,,卷期:2009年27-3]
- Mesenchymal stem cells within the bone are responsible for the generation of osteoblasts, chondrocytes, and adipocytes. In rodents, Indian hedgehog has been shown to play a role in osteoblast differentiation. However, ev...
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