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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共25条记录   TET-ering between Pluripotency and Differentiation [作者：Yamanaka, S; Carniol, K,期刊：Cell, 页码：804-804 , 文章类型： News Item，,卷期：2011年145-6] Keeping a Strong Beat in Cardiomyocyte Generation [作者：Yamanaka, S; Carniol, K,期刊：Cell, 页码：804-805 , 文章类型： News Item，,卷期：2011年145-6] Pluripotent Cells Go 3D [作者：Yamanaka, S; Carniol, K,期刊：Cell, 页码：805-805 , 文章类型： News Item，,卷期：2011年145-6] Taking on Complex Disease with iPSCs [作者：Yamanaka, S; Carniol, K,期刊：Cell, 页码：805-805 , 文章类型： News Item，,卷期：2011年145-6] Reprogramming: What's Unknown? [作者：Daley, GQ; Surani, A; Tanaka, E; Plath, K,期刊：Cell, 页码：811-812 , 文章类型： Editorial Material，,卷期：2011年145-6] Treating the Periphery to Ameliorate Neurodegenerative Diseases [作者：Reinhart, PH; Kelly, JW,期刊：Cell, 页码：813-814 , 文章类型： Editorial Material，,卷期：2011年145-6] Abnormalities in the kynurenine pathway are associated with neurodegenerative disorders. Zwilling et al. (2011) show that inhibition of kynurenine 3-monooxygenase in the body's periphery leads to an increase in kyneuric ... Rolling ES Cells Down the Waddington Landscape with Oct4 and Sox2 [作者：Iovino, N; Cavalli, G,期刊：Cell, 页码：815-817 , 文章类型： Editorial Material，,卷期：2011年145-6] Embryonic stem cell (ESC) pluripotency is maintained by core transcriptional circuits whereby critical factors sustain their own expression while preventing the expression of genes required for differentiation. Thomson e... A Kinesin in Command of Primary Ciliogenesis [作者：Pearson, CG,期刊：Cell, 页码：817-819 , 文章类型： Editorial Material，,卷期：2011年145-6] Primary cilia sense extracellular cues and in response transmit signals required for development and tissue homeostasis. A new study by Kobayashi et al. (2011) reports that the kinesin Kif24 controls the formation of pri... Democracy Derived? New Trajectories in Pluripotent Stem Cell Research [作者：Scott, CT; McCormick, JB; DeRouen, MC; Owen-Smith, J,期刊：Cell, 页码：820-826 , 文章类型： Editorial Material，,卷期：2011年145-6] How has the development of human induced pluripotent stem cells (hiPSCs) modified the trajectory of stem cell research? Here, coauthorship networks of stem cell research articles and analysis of cell lines used in stem c... Cell Fate Plug and Play: Direct Reprogramming and Induced Pluripotency [作者：Chambers, SM; Studer, L,期刊：Cell, 页码：827-830 , 文章类型： Review，,卷期：2011年145-6] Building on the discovery that MyoD expression reprograms fibroblasts into muscle, three papers (Vierbuchen et al., 2010; Ieda et al., 2010; Szabo et al., 2010) recently reported the reprogramming of fibroblasts into neu... The Human Brain in a Dish: The Promise of iPSC-Derived Neurons [作者：Dolmetsch, R; Geschwind, DH,期刊：Cell, 页码：831-834 , 文章类型： Review，,卷期：2011年145-6] Induced pluripotent stem cell-derived neurons from patients promise to fill an important niche between studies in humans and model organisms in deciphering mechanisms and identifying therapeutic avenues for neurologic an... Chromatin Connections to Pluripotency and Cellular Reprogramming [作者：Orkin, SH; Hochedlinger, K,期刊：Cell, 页码：835-850 , 文章类型： Review，,卷期：2011年145-6] The pluripotent state of embryonic stem cells (ESCs) provides a unique perspective on regulatory programs that govern self-renewal and differentiation and somatic cell reprogramming. Here, we review the highly connected ... Strategies for Homeostatic Stem Cell Self-Renewal in Adult Tissues [作者：Simons, BD; Clevers, H,期刊：Cell, 页码：851-862 , 文章类型： Review，,卷期：2011年145-6] In adult tissues, an exquisite balance exists between stem cell proliferation and the generation of differentiated offspring. Classically, it has been argued that this balance is obtained at the level of a single stem ce... Kynurenine 3-Monooxygenase Inhibition in Blood Ameliorates Neurodegeneration [作者：Zwilling, D; Huang, SY; Sathyasaikumar, KV; Notarangelo, FM; Guidetti, P; Wu, HQ; Lee, J; Truong, J; Andrews-Zwilling, Y; Hsieh, EW; Louie, JY; Wu, T; Scearce-Levie, K; Patrick, C; Adame, A; Giorgini, F; Moussaoui, S; Laue, G; Rassoulpour, A; Flik, G; Hua,期刊：Cell, 页码：863-874 , 文章类型： Article，,卷期：2011年145-6] Metabolites in the kynurenine pathway, generated by tryptophan degradation, are thought to play an important role in neurodegenerative disorders, including Alzheimer's and Huntington's diseases. In these disorders, gluta... Pluripotency Factors in Embryonic Stem Cells Regulate Differentiation into Germ Layers [作者：Thomson, M; Liu, SJ; Zou, LN; Smith, Z; Meissner, A; Ramanathan, S,期刊：Cell, 页码：875-889 , 文章类型： Article，,卷期：2011年145-6] Cell fate decisions are fundamental for development, but we do not know how transcriptional networks reorganize during the transition from a pluripotent to a differentiated cell state. Here, we asked how mouse embryonic ... The RNA Helicase Mtr4p Modulates Polyadenylation in the TRAMP Complex [作者：Jia, HJ; Wang, XY; Liu, F; Guenther, UP; Srinivasan, S; Anderson, JT; Jankowsky, E,期刊：Cell, 页码：890-901 , 文章类型： Article，,卷期：2011年145-6] Many steps in nuclear RNA processing, surveillance, and degradation require TRAMP, a complex containing the poly(A) polymerase Trf4p, the Zn-knuckle protein Air2p, and the RNA helicase Mtr4p. TRAMP polyadenylates RNAs de...