- The tyrosine kinase Syk regulates the survival of chronic lymphocytic leukemia B cells through PKC delta and proteasome-dependent regulation of Mcl-1 expression
[作者：Baudot, AD; Jeandel, PY; Mouska, X; Maurer, U; Tartare-Deckert, S; Raynaud, SD; Cassuto, JP; Ticchioni, M; Deckert, M,期刊：Oncogene, 页码：3261-3273 , 文章类型： Article，,卷期：2009年28-37]
- B-cell chronic lymphocytic leukemia (B-CLL) is characterized by accumulation of mature monoclonal CD5+ B cells. The disease results mainly from a failure of cells to undergo apoptosis, a process largely influenced by the...
- Cancer targeted gene therapy of BikDD inhibits orthotopic lung cancer growth and improves long-term survival
[作者：Sher, YP; Tzeng, TF; Kan, SF; Hsu, J; Xie, X; Han, Z; Lin, WC; Li, LY; Hung, MC,期刊：Oncogene, 页码：3286-3295 , 文章类型： Article，,卷期：2009年28-37]
- Lung cancer is a leading cause of cancer death due to the high incidence of metastasis; therefore, novel and effective treatments are urgently needed. A current strategy is cancer-specific targeted gene therapy. Although...
- Effect of single-chain antibody targeting of the ligand-binding domain in the anaplastic lymphoma kinase receptor
[作者：Stylianou, DC; Maur, AAD; Kodack, DP; Henke, RT; Hohn, S; Toretsky, JA; Riegel, AT; Wellstein, A,期刊：Oncogene, 页码：3296-3306 , 文章类型： Article，,卷期：2009年28-37]
- The tyrosine kinase receptor anaplastic lymphoma kinase (ALK) and its ligand, the growth factor pleiotrophin (PTN), are highly expressed during the development of the nervous system and have been implicated in the malign...
- Onconeuronal cerebellar degeneration-related antigen, Cdr2, is strongly expressed in papillary renal cell carcinoma and leads to attenuated hypoxic response
[作者：Balamurugan, K; Luu, VD; Kaufmann, MR; Hofmann, VS; Boysen, G; Barth, S; Bordoli, MR; Stiehl, DP; Moch, H; Schraml, P; Wenger, RH; Camenisch, G,期刊：Oncogene, 页码：3274-3285 , 文章类型： Article，,卷期：2009年28-37]
- The onconeuronal cerebellar degeneration-related antigen Cdr2 is associated with paraneoplastic syndromes. Neoplastic expression of Cdr2 in ovary and breast tumors triggers an autoimmune response that suppresses tumor gr...
- Overexpression of Csk-binding protein contributes to renal cell carcinogenesis
[作者：Feng, X; Lu, X; Man, X; Zhou, W; Jiang, LQ; Knyazev, P; Lei, L; Huang, Q; Ullrich, A; Zhang, Z; Chen, Z,期刊：Oncogene, 页码：3320-3331 , 文章类型： Article，,卷期：2009年28-37]
- C-terminal Src kinase (Csk)-binding protein (Cbp) is a transmembrane adaptor protein that localizes exclusively in lipid rafts, where it regulates Src family kinase (SFK) activities through recruitment of Csk. Although S...
- Heat shock protein 27 is involved in SUMO-2/3 modification of heat shock factor 1 and thereby modulates the transcription factor activity
[作者：Simioni, MB; De Thonel, A; Hammann, A; Joly, AL; Bossis, G; Fourmaux, E; Bouchot, A; Landry, J; Piechaczyk, M; Garrido, C,期刊：Oncogene, 页码：3332-3344 , 文章类型： Article，,卷期：2009年28-37]
- Heat shock protein 27 (HSP27) accumulates in stressed cells and helps them to survive adverse conditions. We have already shown that HSP27 has a function in the ubiquitination process that is modulated by its oligomeriza...
- Loss of Nkx3.1 leads to the activation of discrete downstream target genes during prostate tumorigenesis
[作者：Song, H; Zhang, B; Watson, MA; Humphrey, PA; Lim, H; Milbrandt, J,期刊：Oncogene, 页码：3307-3319 , 文章类型： Article，,卷期：2009年28-37]
- The expression of NKX3.1, a transcriptional regulator and tumor suppressor gene in prostate cancer, is downregulated during early stages of prostate tumorigenesis. However, little is known of the alterations in gene expr...
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