- LMO4 is an essential mediator of ErbB2/HER2/Neu-induced breast cancer cell cycle progression
[作者：Montanez-Wiscovich, ME; Seachrist, DD; Landis, MD; Visvader, J; Andersen, B; Keri, RA,期刊：Oncogene, 页码：3608-3618 , 文章类型： Article，,卷期：2009年28-41]
- ErbB2/HER2/Neu-overexpressing breast cancers are characterized by poor survival due to high proliferation and metastasis rates and identifying downstream targets of ErbB2 should facilitate developing novel therapies for ...
- Regulation of p53 expression, phosphorylation and subcellular localization by a G-protein-coupled receptor
[作者：Solyakov, L; Sayan, E; Riley, J; Pointon, A; Tobin, AB,期刊：Oncogene, 页码：3619-3630 , 文章类型： Article，,卷期：2009年28-41]
- G-protein-coupled receptors (GPCRs) have been extremely successful drug targets for a multitude of diseases from heart failure to depression. This superfamily of cell surface receptors have not, however, been widely cons...
- Plk1 regulates liver tumor cell death by phosphorylation of TAp63
[作者：Komatsu, S; Takenobu, H; Ozaki, T; Ando, K; Koida, N; Suenaga, Y; Ichikawa, T; Hishiki, T; Chiba, T; Iwama, A; Yoshida, H; Ohnuma, N; Nakagawara, A; Kamijo, T,期刊：Oncogene, 页码：3631-3641 , 文章类型： Article，,卷期：2009年28-41]
- We previously found that Plk1 inhibited the p53/p73 activity through its direct phosphorylation. In this study, we investigated the functional role of Plk1 in modulating the p53 family member TAp63, resulting in the cont...
- Nedd9/Hef1/Cas-L mediates the effects of environmental pollutants on cell migration and plasticity
[作者：Bui, LC; Tomkiewicz, C; Chevallier, A; Pierre, S; Bats, AS; Mota, S; Raingeaud, J; Pierre, J; Diry, M; Transy, C; Garlatti, M; Barouki, R; Coumoul, X,期刊：Oncogene, 页码：3642-3651 , 文章类型： Article，,卷期：2009年28-41]
- Aryl hydrocarbon receptor (AhR), or dioxin receptor, is a transcription factor that induces adaptive metabolic pathways in response to environmental pollutants. Recently, other pathways were found to be altered by AhR an...
- Inhibition of PI-3K restores nuclear p27(Kip1) expression in a mouse model of Kras-driven lung cancer
[作者：Kelly-Spratt, KS; Philipp-Staheli, J; Gurley, KE; Hoon-Kim, K; Knoblaugh, S; Kemp, CJ,期刊：Oncogene, 页码：3652-3662 , 文章类型： Article，,卷期：2009年28-41]
- Reduced expression of the CDK inhibitor p27(Kip1) (p27) in human lung cancer correlates with tumor aggressiveness and poor prognosis. However, the regulation of p27 expression and the role of p27 during lung cancer are p...
- Nuclear LYRIC/AEG-1 interacts with PLZF and relieves PLZF-mediated repression
[作者：Thirkettle, HJ; Mills, IG; Whitaker, HC; Neal, DE,期刊：Oncogene, 页码：3663-3670 , 文章类型： Article，,卷期：2009年28-41]
- LYRIC/AEG-1 and its altered expression have been linked to carcinogenesis in prostate, brain and melanoma as well as promoting chemoresistance and metastasis in breast cancer. LYRIC/AEG-1 function remains unclear, althou...
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