- Upregulation of lactate dehydrogenase A by ErbB2 through heat shock factor 1 promotes breast cancer cell glycolysis and growth
[作者:Zhao, YH; Zhou, M; Liu, H; Ding, Y; Khong, HT; Yu, D; Fodstad, O; Tan, M,期刊:Oncogene, 页码:3689-3701 , 文章类型: Article,,卷期:2009年28-42]
- ErbB2 has been shown to activate signaling molecules that may regulate glucose metabolism. However, there is no evidence reported to directly link ErbB2 to glycolysis, and the mechanism underlying ErbB2-enhanced glycolys...
- Kruppel-like factor 5 promotes breast cell proliferation partially through upregulating the transcription of broblast growth factor binding protein 1
[作者:Zheng, HQ; Zhou, Z; Huang, J; Chaudhury, L; Dong, JT; Chen, C,期刊:Oncogene, 页码:3702-3713 , 文章类型: Article,,卷期:2009年28-42]
- The Kruppel-like factor 5 (KLF5) is a zinc-finger transcription factor promoting cell proliferation, cell-cycle progression and survival. A high expression level of KLF5 mRNA has been shown to be associated with shorter ...
- Calreticulin promotes cell motility and enhances resistance to anoikis through STAT3-CTTN-Akt pathway in esophageal squamous cell carcinoma
[作者:Du, XL; Yang, H; Liu, SG; Luo, ML; Hao, JJ; Zhang, Y; Lin, DC; Xu, X; Cai, Y; Zhan, QM; Wang, MR,期刊:Oncogene, 页码:3714-3722 , 文章类型: Article,,卷期:2009年28-42]
- We have shown earlier that overexpression of Calreticulin (CRT) contributed to a poor prognosis for patients with esophageal squamous cell carcinoma (ESCC). Here, we have shown an important role of CRT in tumorigenesis t...
- Functional interaction of HTLV-1 Tax protein with the POZ domain of the transcriptional repressor BCL6
[作者:Dean, J; Hashimoto, K; Tsuji, T; Gautier, V; Hall, WW; Sheehy, N,期刊:Oncogene, 页码:3723-3734 , 文章类型: Article,,卷期:2009年28-42]
- The Tax protein encoded by human T-cell leukaemia virus type 1 (HTLV-1) has a pivotal role in T-cell transformation by deregulating cellular signalling pathways. Using the yeast two-hybrid system to screen a human leukoc...
- The prolyl isomerase Pin1 regulates the NF-kappa B signaling pathway and interleukin-8 expression in glioblastoma
[作者:Atkinson, GP; Nozell, SE; Harrison, DK; Stonecypher, MS; Chen, D; Benveniste, EN,期刊:Oncogene, 页码:3735-3745 , 文章类型: Article,,卷期:2009年28-42]
- The brain tumor glioblastoma (GBM) remains one of the most aggressive and devastating tumors despite decades of effort to find more effective treatments. A hallmark of GBM is the constitutive activation of the nuclear fa...
- Yin Yang 1 regulates the transcriptional activity of androgen receptor
[作者:Deng, Z; Wan, M; Cao, P; Rao, A; Cramer, SD; Sui, G,期刊:Oncogene, 页码:3746-3757 , 文章类型: Article,,卷期:2009年28-42]
- The multifunctional protein Yin Yang 1 (YY1) has an important role in epigenetic regulation of gene expression. YY1 is highly expressed in various types of cancers, including prostate cancer. Currently, the mechanism und...
- Disruption of the Pdcd4 tumor suppressor gene in chicken DT40 cells reveals its role in the DNA-damage response
[作者:Singh, P; Marikkannu, R; Bitomsky, N; Klempnauer, KH,期刊:Oncogene, 页码:3758-3764 , 文章类型: Article,,卷期:2009年28-42]
- The programmed cell death gene 4 (Pdcd4) gene has been implicated as a new tumor suppressor gene in the development of several types of human cancer. Pdcd4 interacts with the translation initiation factor, eIF4A, and is ...
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