- Hepatic tumor-stroma crosstalk guides epithelial to mesenchymal transition at the tumor edge
[作者：van Zijl, F; Mair, M; Csiszar, A; Schneller, D; Zulehner, G; Huber, H; Eferl, R; Beug, H; Dolznig, H; Mikulits, W,期刊：Oncogene, 页码：4022-4033 , 文章类型： Article，,卷期：2009年28-45]
- The tumor-stroma crosstalk is a dynamic process fundamental in tumor development. In hepatocellular carcinoma (HCC), the progression of malignant hepatocytes frequently depends on transforming growth factor (TGF)-beta pr...
- Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1 alpha
[作者：Soeda, A; Park, M; Lee, D; Mintz, A; Androutsellis-Theotokis, A; McKay, RD; Engh, J; Iwama, T; Kunisada, T; Kassam, AB; Pollack, IF; Park, DM,期刊：Oncogene, 页码：3949-3959 , 文章类型： Article，,卷期：2009年28-45]
- Hypoxia contributes to the progression of a variety of cancers by activating adaptive transcriptional programs that promote cell survival, motility and tumor angiogenesis. Although the importance of hypoxia and subsequen...
- Impaired PTPN13 phosphatase activity in spontaneous or HPV-induced squamous cell carcinomas potentiates oncogene signaling through the MAP kinase pathway
[作者：Hoover, AC; Strand, GL; Nowicki, PN; Anderson, ME; Vermeer, PD; Klingelhutz, AJ; Bossler, AD; Pottala, JV; Hendriks, WJAJ; Lee, JH,期刊：Oncogene, 页码：3960-3970 , 文章类型： Article，,卷期：2009年28-45]
- Human papillomaviruses (HPVs) are a causative factor in over 90% of cervical and 25% of head and neck squamous cell carcinomas (HNSCCs). The C terminus of the high-risk HPV 16 E6 oncoprotein physically associates with an...
- Leupaxin acts as a mediator in prostate carcinoma progression through deregulation of p120catenin expression
[作者：Kaulfuss, S; von Hardenberg, S; Schweyer, S; Herr, AM; Laccone, F; Wolf, S; Burfeind, P,期刊：Oncogene, 页码：3971-3982 , 文章类型： Article，,卷期：2009年28-45]
- Recently, we could show that the focal adhesion protein leupaxin (LPXN) is expressed in human prostate carcinomas (PCa) and induces invasiveness of androgen-independent PCa cells. In this study we show that LPXN enhanced...
- Reactivating HIF prolyl hydroxylases under hypoxia results in metabolic catastrophe and cell death
[作者：Tennant, DA; Frezza, C; MacKenzie, ED; Nguyen, QD; Zheng, L; Selak, MA; Roberts, DL; Dive, C; Watson, DG; Aboagye, EO; Gottlieb, E,期刊：Oncogene, 页码：4009-4021 , 文章类型： Article，,卷期：2009年28-45]
- Cells exposed to low-oxygen conditions (hypoxia) alter their metabolism to survive. This response, although vital during development and high-altitude survival, is now known to be a major factor in the selection of cells...
- Increased proteasome subunit protein expression and proteasome activity in colon cancer relate to an enhanced activation of nuclear factor E2-related factor 2 (Nrf2)
[作者：Arlt, A; Bauer, I; Schafmayer, C; Tepel, J; Muerkoster, SS; Brosch, M; Roder, C; Kalthoff, H; Hampe, J; Moyer, MP; Folsch, UR; Schafer, H,期刊：Oncogene, 页码：3983-3996 , 文章类型： Article，,卷期：2009年28-45]
- An elevated proteasome activity contributes to tumorigenesis, particularly by providing cancer cells with antiapoptotic protection and efficient clearance from irregular proteins. Still, the underlying mechanisms are poo...
- A restricted signature of miRNAs distinguishes APL blasts from normal promyelocytes
[作者：Careccia, S; Mainardi, S; Pelosi, A; Gurtner, A; Diverio, D; Riccioni, R; Testa, U; Pelosi, E; Piaggio, G; Sacchi, A; Lavorgna, S; Lo-Coco, F; Blandino, G; Levrero, M; Rizzo, MG,期刊：Oncogene, 页码：4034-4040 , 文章类型： Article，,卷期：2009年28-45]
- MicroRNAs (miRNAs) are small non-coding RNAs involved in the regulation of critical cell processes such as apoptosis, cell proliferation and differentiation. A small set of miRNAs is differentially expressed in hematopoi...
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