Ceftobiprole is a novel parenteral cephalosporin with high affinity for most penicillin-binding proteins, including the mecA product penicillin-binding protein (PBP) 2a, rendering it active against methicillin-resista...

Tramadol hydrochloride is a widely prescribed, centrally acting analgesic marketed in over 90 countries. Before being released in the U.S. in 1995, the drug had been available in Europe for almost two decades. Thus, t...

Certolizumab pegol is a humanized Fab' fragment monoclonal antibody to tumor necrosis factor alpha (TNF-alpha). PEGylation increases its half-life, and it is administered subcutaneously to treat immune-mediated inflam...

Exercise is the most common trigger of bronchospasm in children with asthma. Exercise-induced bronchoconstriction (EIB) occurs in up to 90% of individuals with asthma who are not under antiinflammatory treatment and i...

Budesonide is a promising drug for a variety of documented applications and has potential in gastroenterology. Its unique local mechanism of delivery and efficient first-pass metabolism, resulting in fewer systemic ad...

The Society for Endocrinology (BES) held its Annual Conference April 7-10, 2008, in Harrogate, UK. The meeting was devoted to different areas of endocrinology such as diabetes, diseases of both anterior and posterior ...