- Recent advances in the search for D-3- and D-4-selective drugs: probes, models and candidates
[作者:Lober, S; Hubner, H; Tschammer, N; Gmeiner, P,期刊:Trends in Pharmacological Sciences, 页码:148-157 , 文章类型: Review,,卷期:2011年32-3]
- Dopamine D-2-like receptors (including D-2, D-3 and D-4) belong to the 'rhodopsin-like' family of G protein-coupled receptors (GPCRs), which represent the largest group of targets for bioactive molecules. Due to their hi...
- Rho-associated coiled-coil-forming kinases (ROCKs): potential targets for the treatment of atherosclerosis and vascular disease
[作者:Zhou, QA; Gensch, C; Liao, JK,期刊:Trends in Pharmacological Sciences, 页码:167-173 , 文章类型: Review,,卷期:2011年32-3]
- ROCKs are important regulators of the actin cytoskeleton. Because changes in the actin cytoskeleton underlie vascular contractility and remodeling, inflammatory cell recruitment, and cell proliferation, it is likely that...
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