- Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria
[作者：Ivanov, II; Atarashi, K; Manel, N; Brodie, EL; Shima, T; Karaoz, U; Wei, DG; Goldfarb, KC; Santee, CA; Lynch, SV; Tanoue, T; Imaoka, A; Itoh, K; Takeda, K; Umesaki, Y; Honda, K; Littman, DR,期刊：Cell, 页码：485-498 , 文章类型： Article，,卷期：2009年139-3]
- The gastrointestinal tract of mammals is inhabited by hundreds of distinct species of commensal microorganisms that exist in a mutualistic relationship with the host. How commensal microbiota influence the host immune sy...
- Tetherin Inhibits HIV-1 Release by Directly Tethering Virions to Cells
[作者：Perez-Caballero, D; Zang, T; Ebrahimi, A; McNatt, MW; Gregory, DA; Johnson, MC; Bieniasz, PD,期刊：Cell, 页码：499-511 , 文章类型： Article，,卷期：2009年139-3]
- Tetherin is an interferon-induced protein whose expression blocks the release of HIV-1 and other enveloped viral particles. The underlying mechanism by which tetherin functions and whether it directly or indirectly cause...
- beta-Arrestin1 Regulates Zebrafish Hematopoiesis through Binding to YY1 and Relieving Polycomb Group Repression
[作者：Yue, R; Kang, JH; Zhao, C; Hu, WX; Tang, YW; Liu, XS; Pei, G,期刊：Cell, 页码：535-546 , 文章类型： Article，,卷期：2009年139-3]
- beta-Arrestin1 is a multifunctional protein critically involved in signal transduction. Recently, it is also identified as a nuclear transcriptional regulator, but the underlying mechanisms and physiological significance...
- The Yeast Exosome Functions as a Macromolecular Cage to Channel RNA Substrates for Degradation
[作者：Bonneau, F; Basquin, J; Ebert, J; Lorentzen, E; Conti, E,期刊：Cell, 页码：547-559 , 文章类型： Article，,卷期：2009年139-3]
- The exosome is a conserved macromolecular complex essential for RNA degradation. The nine-subunit core of the eukaryotic exosome shares a similar barrel-like architecture with prokaryotic complexes, but is catalytically ...
- Regulation of MBK-2/DYRK by CDK-1 and the Pseudophosphatases EGG-4 and EGG-5 during the Oocyte-to-Embryo Transition
[作者：Cheng, KCC; Klancer, R; Singson, A; Seydoux, G,期刊：Cell, 页码：560-572 , 文章类型： Article，,卷期：2009年139-3]
- DYRKs are kinases that self-activate in vitro by autophosphorylation of a YTY motif in the kinase domain, but their regulation in vivo is not well understood. In C. elegans zygotes, MBK-2/DYRK phosphorylates oocyte prote...
- PI3 Kinase Signals BCR-Dependent Mature B Cell Survival
[作者：Srinivasan, L; Sasaki, Y; Calado, DP; Zhang, BC; Paik, JH; DePinho, RA; Kutok, JL; Kearney, JF; Otipoby, KL; Rajewsky, K,期刊：Cell, 页码：573-586 , 文章类型： Article，,卷期：2009年139-3]
- Previous work has shown that mature B cells depend upon survival signals delivered to the cells by their antigen receptor (BCR). To identify the molecular nature of this survival signal, we have developed a genetic appro...
- Polycystin-1 and-2 Dosage Regulates Pressure Sensing
[作者：Sharif-Naeini, R; Folgering, JHA; Bichet, D; Duprat, F; Lauritzen, I; Arhatte, M; Jodar, M; Dedman, A; Chatelain, FC; Schulte, U; Retailleau, K; Loufrani, L; Patel, A; Sachs, F; Delmas, P; Peters, DJM; Honore, E,期刊：Cell, 页码：587-596 , 文章类型： Article，,卷期：2009年139-3]
- Autosomal-dominant polycystic kidney disease, the most frequent monogenic cause of kidney failure, is induced by mutations in the PKD1 or PKD2 genes, encoding polycystins TRPP1 and TRPP2, respectively. Polycystins are pr...
- Retinoic Acid from the Meninges Regulates Cortical Neuron Generation
[作者：Siegenthaler, JA; Ashique, AM; Zarbalis, K; Patterson, KP; Hecht, JH; Kane, MA; Folias, AE; Choe, Y; May, SR; Kume, T; Napoli, JL; Peterson, AS; Pleasure, SJ,期刊：Cell, 页码：597-609 , 文章类型： Article，,卷期：2009年139-3]
- Extrinsic signals controlling generation of neocortical neurons during embryonic life have been difficult to identify. In this study we demonstrate that the dorsal forebrain meninges communicate with the adjacent radial ...
- Profiling the Human Protein-DNA Interactome Reveals ERK2 as a Transcriptional Repressor of Interferon Signaling
[作者：Hu, SH; Xie, Z; Onishi, A; Yu, XP; Jiang, LZ; Lin, J; Rho, HS; Woodard, C; Wang, H; Jeong, JS; Long, SY; He, XF; Wade, H; Blackshaw, S; Qian, J; Zhu, H,期刊：Cell, 页码：610-622 , 文章类型： Article，,卷期：2009年139-3]
- Protein-DNA interactions (PDIs) mediate a broad range of functions essential for cellular differentiation, function, and survival. However, it is still a daunting task to comprehensively identify and profile sequence-spe...
- Analysis of Cell Fate from Single-Cell Gene Expression Profiles in C. elegans
[作者：Liu, X; Long, FH; Peng, HC; Aerni, SJ; Jiang, M; Sanchez-Blanco, A; Murray, JI; Preston, E; Mericle, B; Batzoglou, S; Myers, EW; Kim, SK,期刊：Cell, 页码：623-633 , 文章类型： Article，,卷期：2009年139-3]
- The C. elegans cell lineage provides a unique opportunity to look at how cell lineage affects patterns of gene expression. We developed an automatic cell lineage analyzer that converts high-resolution images of worms int...
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