- Dissociation of EphB2 Signaling Pathways Mediating Progenitor Cell Proliferation and Tumor Suppression
[作者：Genander, M; Halford, MM; Xu, NJ; Eriksson, M; Yu, ZR; Qiu, ZZ; Martling, A; Greicius, G; Thakar, S; Catchpole, T; Chumley, MJ; Zdunek, S; Wang, CG; Holm, T; Goff, SP; Pettersson, S; Pestell, RG; Henkemeyer, M; Frisen, J,期刊：Cell, 页码：679-692 , 文章类型： Article，,卷期：2009年139-4]
- Signaling proteins driving the proliferation of stem and progenitor cells are often encoded by protooncogenes. EphB receptors represent a rare exception; they promote cell proliferation in the intestinal epithelium and f...
- An Epigenetic Switch Involving NF-kappa B, Lin28, Let-7 MicroRNA, and IL6 Links Inflammation to Cell Transformation
[作者：Iliopoulos, D; Hirsch, HA; Struhl, K,期刊：Cell, 页码：693-706 , 文章类型： Article，,卷期：2009年139-4]
- Inflammation is linked clinically and epidemiologically to cancer, and NF-kappa B appears to play a causative role, but the mechanisms are poorly understood. We show that transient activation of Src oncoprotein can media...
- Nonoptimal Microbial Response to Antibiotics Underlies Suppressive Drug Interactions
[作者：Bollenbach, T; Quan, S; Chait, R; Kishony, R,期刊：Cell, 页码：707-718 , 文章类型： Article，,卷期：2009年139-4]
- Suppressive drug interactions, in which one antibiotic can actually help bacterial cells to grow faster in the presence of another, occur between protein and DNA synthesis inhibitors. Here, we show that this suppression ...
- Concerted Loading of Mcm2-7 Double Hexamers around DNA during DNA Replication Origin Licensing
[作者：Remus, D; Beuron, F; Tolun, G; Griffith, JD; Morris, EP; Diffley, JFX,期刊：Cell, 页码：719-730 , 文章类型： Article，,卷期：2009年139-4]
- The licensing of eukaryotic DNA replication origins, which ensures once-per-cell-cycle replication, involves the loading of six related minichromosome maintenance proteins (Mcm2-7) into prereplicative complexes (pre-RCs)...
- Singularity in Polarization: Rewiring Yeast Cells to Make Two Buds
[作者：Howell, AS; Savage, NS; Johnson, SA; Bose, I; Wagner, AW; Zyla, TR; Nijhout, HF; Reed, MC; Goryachev, AB; Lew, DJ,期刊：Cell, 页码：731-743 , 文章类型： Article，,卷期：2009年139-4]
- For budding yeast to ensure formation of only one bud, cells must polarize toward one, and only one, site. Polarity establishment involves the Rho family GTPase Cdc42, which concentrates at polarization sites via a posit...
- Nuclear CDKs Drive Smad Transcriptional Activation and Turnover in BMP and TGF-beta Pathways
[作者：Alarcon, C; Zaromytidou, AI; Xi, QR; Gao, S; Yu, JZ; Fujisawa, S; Barlas, A; Miller, AN; Manova-Todorova, K; Macias, MJ; Sapkota, G; Pan, DJ; Massague, J,期刊：Cell, 页码：757-769 , 文章类型： Article，,卷期：2009年139-4]
- TGF-beta and BMP receptor kinases activate Smad transcription factors by C-terminal phosphorylation. We have identified a subsequent agonist-induced phosphorylation that plays a central dual role in Smad transcriptional ...
- A trans-Acting Riboswitch Controls Expression of the Virulence Regulator PrfA in Listeria monocytogenes
[作者：Loh, E; Dussurget, O; Gripenland, J; Vaitkevicius, K; Tiensuu, T; Mandin, P; Repoila, F; Buchrieser, C; Cossart, P; Johansson, J,期刊：Cell, 页码：770-779 , 文章类型： Article，,卷期：2009年139-4]
- Riboswitches are RNA elements acting in cis, controlling expression of their downstream genes through a metabolite-induced alteration of their secondary structure. Here, we demonstrate that two S-adenosylmethionine (SAM)...
- Structural Convergence between Cryo-EM and NMR Reveals Intersubunit Interactions Critical for HIV-1 Capsid Function
[作者：Byeon, IJL; Meng, X; Jung, JW; Zhao, GP; Yang, RF; Ahn, JW; Shi, J; Concel, J; Aiken, C; Zhang, PJ; Gronenborn, AM,期刊：Cell, 页码：780-790 , 文章类型： Article，,卷期：2009年139-4]
- Mature HIV-1 particles contain conical-shaped capsids that enclose the viral RNA genome and perform essential functions in the virus life cycle. Previous structural analysis of two-and three-dimensional arrays of the cap...
- Cdc42-Mediated Tubulogenesis Controls Cell Specification
[作者：Kesavan, G; Sand, FW; Greiner, TU; Johansson, JK; Kobberup, S; Wu, XW; Brakebusch, C; Semb, H,期刊：Cell, 页码：791-801 , 文章类型： Article，,卷期：2009年139-4]
- Understanding how cells polarize and coordinate tubulogenesis during organ formation is a central question in biology. Tubulogenesis often coincides with cell-lineage specification during organ development. Hence, an ele...
- Adult Neurogenesis Modulates the Hippocampus-Dependent Period of Associative Fear Memory
[作者：Kitamura, T; Saitoh, Y; Takashima, N; Murayama, A; Niibori, Y; Ageta, H; Sekiguchi, M; Sugiyama, H; Inokuchi, K,期刊：Cell, 页码：814-827 , 文章类型： Article，,卷期：2009年139-4]
- Acquired memory initially depends on the hippocampus (HPC) for the process of cortical permanent memory formation. The mechanisms through which memory becomes progressively independent from the HPC remain unknown. In the...
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