- Driving Biofuels from Field to Fuel Tank
[作者：Gura, T,期刊：Cell, 页码：9-12 , 文章类型： Editorial Material，,卷期：2009年138-1]
- Rising oil prices, fears of global warming, and instability in oil-producing countries have ignited the rush to produce biofuels from plants. The science is progressing rapidly, driven by favorable policies and generous ...
- Teeing Up Transcription on CpG Islands
[作者：Singh, H,期刊：Cell, 页码：14-16 , 文章类型： Editorial Material，,卷期：2009年138-1]
- Eukaryotic cells use elaborate molecular mechanisms to rapidly activate signal-dependent gene expression. New work provides fresh insights into these mechanisms by demonstrating that CpG islands in promoters are nucleoso...
- Disorder, Promiscuity, and Toxic Partnerships
[作者：Marcotte, EM; Tsechansky, M,期刊：Cell, 页码：16-18 , 文章类型： Editorial Material，,卷期：2009年138-1]
- Many genes are toxic when overexpressed, but general mechanisms for this toxicity have proven elusive. Vavouri et al. (2009) find that intrinsic protein disorder and promiscuous molecular interactions are strong determin...
- Chromatin Places Metabolism Center Stage
[作者：Ladurner, AG,期刊：Cell, 页码：18-20 , 文章类型： Editorial Material，,卷期：2009年138-1]
- Dynamic changes in histone and transcription factor acetylation modulate gene expression. A study in Science (Wellen et al., 2009) reports that changes in glucose metabolism alter the availability of acetyl-CoA, the esse...
- Breaking Up Just Got Easier to Do
[作者：Klein, HL; Symington, LS,期刊：Cell, 页码：20-22 , 文章类型： Editorial Material，,卷期：2009年138-1]
- The SLX4 protein functions as a platform for catalytic subunits of structure-specific endonucleases. Findings reported in Cell (Fekairi et al., 2009; Svendsen et al., 2009) and in Molecular Cell (Andersen et al., 2009; M...
- A Positive Spin on the Centromere
[作者：Dechassa, ML; D'Arcy, S; Luger, K,期刊：Cell, 页码：22-24 , 文章类型： Editorial Material，,卷期：2009年138-1]
- The properties of centromeric nucleosomes have been the subject of considerable debate and controversy. Furuyama and Henikoff (2009) now provide surprising evidence that centromeric nucleosomes wrap DNA in an orientation...
- Getting to First Base in Proteasome Assembly
[作者：Besche, HC; Peth, A; Goldberg, AL,期刊：Cell, 页码：25-28 , 文章类型： Review，,卷期：2009年138-1]
- Assembly of complex structures such as the eukaryotic 26S proteasome requires intricate mechanisms that ensure precise subunit arrangements. Recent studies have shed light on the pathway for ordered assembly of the base ...
- Redefining Chronic Viral Infection
[作者：Virgin, HW; Wherry, EJ; Ahmed, R,期刊：Cell, 页码：30-50 , 文章类型： Review，,卷期：2009年138-1]
- Viruses that cause chronic infection constitute a stable but little-recognized part of our meta-genome: our virome. Ongoing immune responses hold these chronic viruses at bay while avoiding immunopathologic damage to per...
- WNT/TCF Signaling through LEF1 and HOXB9 Mediates Lung Adenocarcinoma Metastasis
[作者：Nguyen, DX; Chiang, AC; Zhang, XHF; Kim, JY; Kris, MG; Ladanyi, M; Gerald, WL; Massague, J,期刊：Cell, 页码：51-62 , 文章类型： Article，,卷期：2009年138-1]
- Metastasis from lung adenocarcinoma can occur swiftly to multiple organs within months of diagnosis. The mechanisms that confer this rapid metastatic capacity to lung tumors are unknown. Activation of the canonical WNT/T...
- Mammalian BTBD12/SLX4 Assembles A Holliday Junction Resolvase and Is Required for DNA Repair
[作者：Svendsen, JM; Smogorzewska, A; Sowa, ME; O'Connell, BC; Gygi, SP; Elledge, SJ; Harper, JW,期刊：Cell, 页码：63-77 , 文章类型： Article，,卷期：2009年138-1]
- Structure-specific endonucleases mediate cleavage of DNA structures formed during repair of collapsed replication forks and double-strand breaks (DSBs). Here, we identify BTBD12 as the human ortholog of the budding yeast...
- Human SLX4 Is a Holliday Junction Resolvase Subunit that Binds Multiple DNA Repair/Recombination Endonucleases
[作者：Fekairi, S; Scaglione, S; Chahwan, C; Taylor, ER; Tissier, A; Coulon, S; Dong, MQ; Ruse, C; Yates, JR; Russell, P; Fuchs, RP; McGowan, CH; Gaillard, PHL,期刊：Cell, 页码：78-89 , 文章类型： Article，,卷期：2009年138-1]
- Structure-specific endonucleases resolve DNA secondary structures generated during DNA repair and recombination. The yeast 50 flap endonuclease Slx1-Slx4 has received particular attention with the finding that Slx4 has S...
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