- The Intestinal Microbiota Affect Central Levels of Brain-Derived Neurotropic Factor and Behavior in Mice
[作者:Bercik, P; Denou, E; Collins, J; Jackson, W; Lu, J; Jury, J; Deng, YK; Blennerhassett, P; Macri, J; McCoy, KD; Verdu, EF; Collins, SM,期刊:Gastroenterology, 页码:599-U701 , 文章类型: Article,,卷期:2011年141-2]
- BACKGROUND & AIMS: Alterations in the microbial composition of the gastrointestinal tract (dysbiosis) are believed to contribute to inflammatory and functional bowel disorders and psychiatric comorbidities. We examined w...
- Tolerance to Ingested Deamidated Gliadin in Mice is Maintained by Splenic, Type 1 Regulatory T Cells
[作者:Du Pre, MF; Kozijn, AE; van Berkel, LA; ter Borg, MND; Lindenbergh-Kortleve, D; Jensen, LT; Kooy-Winkelaar, Y; Koning, F; Boon, L; Nieuwenhuis, EES; Sollid, LM; Fugger, L; Samsom, JN,期刊:Gastroenterology, 页码:610-U714 , 文章类型: Article,,卷期:2011年141-2]
- BACKGROUND & AIMS: Patients with celiac disease have permanent intolerance to gluten. Because of the high frequency of this disorder (approximately 1 in 100 individuals), we investigated whether oral tolerance to gluten ...
- The Epithelia-Specific Membrane Trafficking Factor AP-1B Controls Gut Immune Homeostasis in Mice
[作者:Takahashi, D; Hase, K; Kimura, S; Nakatsu, F; Ohmae, M; Mandai, Y; Sato, T; Date, Y; Ebisawa, M; Kato, T; Obata, Y; Fukuda, S; Kawamura, YI; Dohi, T; Katsuno, T; Yokosuka, O; Waguri, S; Ohno, H,期刊:Gastroenterology, 页码:621-632 , 文章类型: Article,,卷期:2011年141-2]
- BACKGROUND & AIMS: Epithelial cells that cover the intestinal mucosal surface maintain immune homeostasis and tolerance in the gastrointestinal tract. However, little is known about the molecular mechanisms that regulate...
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