- The Periplasmic Chaperone Skp Facilitates Targeting, Insertion, and Folding of OmpA into Lipid Membranes with a Negative Membrane Surface Potential
[作者:Patel, GJ; Behrens-Kneip, S; Holst, O; Kleinschmidt, JH,期刊:Biochemistry, 页码:10235-10245 , 文章类型: Article,,卷期:2009年48-43]
- The basic biochemical and biophysical principles by which chaperone-bound membrane proteins are targeted to the outer membrane of Gram-negative bacteria for insertion and folding are unknown. Here we compare spontaneous ...
- The Anti-Helminthic Niclosamide Inhibits Wnt/Frizzled1 Signaling
[作者:Chen, MY; Wang, JB; Lu, JY; Bond, MC; Ren, XR; Lyerly, HK; Barak, LS; Chen, W,期刊:Biochemistry, 页码:10267-10274 , 文章类型: Article,,卷期:2009年48-43]
- Wnt proteins bind to seven-transmembrane Frizzled receptors to mediate the important developmental, morphogenetic, and stem cell related tissue-regenerative effects of Writ signaling. Dysregulated Writ signaling is assoc...
- GPR37 Surface Expression Enhancement via N-Terminal Truncation or Protein-Protein Interactions
[作者:Dunham, JH; Meyer, RC; Garcia, EL; Hall, RA,期刊:Biochemistry, 页码:10286-10297 , 文章类型: Article,,卷期:2009年48-43]
- GPR37, also known as the parkin-associated endothelin-like receptor (Pael-R), is an orphan G-protein-coupled receptor (GPCR) that exhibits poor plasma membrane expression when expressed in most Cell types. We Sought to f...
- Structure Elucidation and Preliminary Assessment of Hydrolase Activity of PqsE, the Pseudomonas Quinolone Signal (PQS) Response Protein
[作者:Yu, S; Jensen, V; Seeliger, J; Feldmann, I; Weber, S; Schleicher, E; Haussler, S; Blankenfeldt, W,期刊:Biochemistry, 页码:10298-10307 , 文章类型: Article,,卷期:2009年48-43]
- In bacteria, the transcription of virulence genes is usually controlled by a cell density-dependent process known as "quorum sensing" (QS). QS relies on small diffusible signaling molecules that cross the bacterial cell ...
- Characterization and Structure of the Manganese-Responsive Transcriptional Regulator ScaR
[作者:Stoll, KE; Draper, WE; Kliegman, JI; Golynskiy, MV; Brew-Appiah, RAT; Phillips, RK; Brown, HK; Breyer, WA; Jakubovics, NS; Jenkinson, HF; Brennan, RG; Cohen, SM; Glasfeld, A,期刊:Biochemistry, 页码:10308-10320 , 文章类型: Article,,卷期:2009年48-43]
- The streptococcal coaggregation regulator (ScaR) of Streptococcus gordonii is a manganese-dependent transcriptional regulator. When intracellular manganese concentrations become elevated, ScaR represses transcription of ...
- Mutual Exchange of Kinetic Properties by Extended Mutagenesis in Two Short LOV Domain Proteins from Pseudomonas putida
[作者:Jentzsch, K; Wirtz, A; Circolone, F; Drepper, T; Losi, A; Gartner, W; Jaeger, KE; Krauss, U,期刊:Biochemistry, 页码:10321-10333 , 文章类型: Article,,卷期:2009年48-43]
- We previously characterized a LOV protein PpSB2-LOV, present in the common soil bacterium Pseudomonas putida, that exhibits a plant phototropin LOV-like photochemistry [Krauss, U., Losi, A., Gartner, W., Jaeger, K. E., a...
- Mechanistic Investigation of the Endo-alpha-N-acetylgalactosaminidase from Streptococcus pneumoniae R6
[作者:Willis, LM; Zhang, R; Reid, A; Withers, SG; Wakarchuk, WW,期刊:Biochemistry, 页码:10334-10341 , 文章类型: Article,,卷期:2009年48-43]
- The large (1767-amino acid) endo-alpha-N-acetylgalactosaminidase from Streptococcus pneumoniae (SpGH101) specifically removes an O-linked disaccharide Gal-beta-1,3-GalNAc-alpha from glycoproteins, While the enzyme from n...
- Molecular Characterization of Flubendiamide Sensitivity in the Lepidopterous Ryanodine Receptor Ca2+ Release Channel
[作者:Kato, K; Kiyonaka, S; Sawaguchi, Y; Tohnishi, M; Masaki, T; Yasokawa, N; Mizuno, Y; Mori, E; Inoue, K; Hamachi, I; Takeshima, H; Mori, Y,期刊:Biochemistry, 页码:10342-10352 , 文章类型: Article,,卷期:2009年48-43]
- Flubendiamide is a benzenedicarboxamide derivative that shows selective insecticidal activity against lepidopterous insects. The specific modulatory effects of flubendiamide on ryanodine binding in insect muscle microsom...
- Biophysical Characterization of Chlamydia trachomatis CT584 Supports Its Potential Role as a Type III Secretion Needle Tip Protein
[作者:Markham, AP; Jaafar, ZA; Kemege, KE; Middaugh, CR; Hefty, PS,期刊:Biochemistry, 页码:10353-10361 , 文章类型: Article,,卷期:2009年48-43]
- Chlamydia are obligate intracellular bacterial pathogens that cause a variety of diseases. Like many Gram-negative bacteria, they employ type III secretion systems (T3SS) for invasion, establishing and maintaining their ...
- Role of Tryptophan-Tryptophan Interactions in Trpzip beta-Hairpin Formation, Structure, and Stability
[作者:Wu, L; McElheny, D; Huang, R; Keiderling, TA,期刊:Biochemistry, 页码:10362-10371 , 文章类型: Article,,卷期:2009年48-43]
- A series of beta-hairpin peptides based on variations of the TrpZip2 sequence, SWTWEN-GKWTWK, of Cochran and co-workers were studied using electronic circular dichroism (CD) and infrared (IR) spectra by varying temperatu...
- Interactions of the Osmolyte Glycine Betaine with Molecular Surfaces in Water: Thermodynamics, Structural Interpretation, and Prediction of m-Values
[作者:Capp, MW; Pegram, LM; Saecker, RM; Kratz, M; Riccardi, D; Wendorff, T; Cannon, JG; Record, MT,期刊:Biochemistry, 页码:10372-10379 , 文章类型: Article,,卷期:2009年48-43]
- Noncovalent self-assembly of biopolymers is driven by molecular interactions between functional groups oil cornplementary biopolymer surfaces, replacing interactions with water. Since individually these interactions are ...
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