- Nrf2 deficiency influences susceptibility to steroid resistance via HDAC2 reduction
[作者:Adenuga, D; Caito, S; Yao, HW; Sundar, IK; Hwang, JW; Chung, S; Rahman, I,期刊:Biochemical and Biophysical Research Communications, 页码:452-456 , 文章类型: Article,,卷期:2010年403-3-4]
- Abnormal lung inflammation and oxidant burden are associated with a significant reduction in histone deacetylase 2 (HDAC2) abundance and steroid resistance. We hypothesized that Nrf2 regulates steroid sensitivity via HDA...
- Mechanism of protein splicing of the Pyrococcus abyssi lon protease intein
[作者:O'Brien, KM; Schufreider, AK; McGill, MA; O'Brien, KM; Reitter, JN; Mills, KV,期刊:Biochemical and Biophysical Research Communications, 页码:457-461 , 文章类型: Article,,卷期:2010年403-3-4]
- Protein splicing is a post-translational process by which an intervening polypeptide, the intein, excises itself from the flanking polypeptides, the exteins, coupled to ligation of the exteins. The Ion protease of Pyroco...
- Protection against dexamethasone-induced muscle atrophy is related to modulation by testosterone of FOXO1 and PGC-1 alpha
[作者:Qin, WP; Pan, JP; Wu, Y; Bauman, WA; Cardozo, C,期刊:Biochemical and Biophysical Research Communications, 页码:473-478 , 文章类型: Article,,卷期:2010年403-3-4]
- Glucocorticoid-induced muscle atrophy results from muscle protein catabolism and reduced protein synthesis, associated with increased expression of two muscle-specific ubiquitin ligases (MAFbx and MuRF1), and of two inhi...
- Transglutaminase 2 gene ablation protects against renal ischemic injury by blocking constant NF-kappa B activation
[作者:Kim, DS; Kim, B; Tahk, H; Kim, DH; Ahn, ER; Choi, C; Jeon, Y; Park, SY; Lee, H; Oh, SH; Kim, SY,期刊:Biochemical and Biophysical Research Communications, 页码:479-484 , 文章类型: Article,,卷期:2010年403-3-4]
- Transglutaminase 2 knockout (TGase2(-/-)) mice show significantly reduced inflammation with decreased myofibroblasts in a unilateral ureteral obstruction (UUO) model, but the mechanism remains to be clarified. Nuclear fa...
- Differential expression and localization of 12/15 lipoxygenases in adipose tissue in human obese subjects
[作者:Dobrian, AD; Lieb, DC; Ma, QA; Lindsay, JW; Cole, BK; Ma, KW; Chakrabarti, SK; Kuhn, NS; Wohlgemuth, SD; Fontana, M; Nadler, JL,期刊:Biochemical and Biophysical Research Communications, 页码:485-490 , 文章类型: Article,,卷期:2010年403-3-4]
- Adipose tissue inflammation in obesity is a major factor leading to cardiovascular disease and type 2 diabetes. 12/15 lipoxygenases (ALOX) play an important role in the generation of inflammatory mediators, insulin resis...
- Glutaredoxin-1 regulates TRAF6 activation and the IL-1 receptor/TLR4 signalling
[作者:Chantzoura, E; Prinarakis, E; Panagopoulos, D; Mosialos, G; Spyrou, G,期刊:Biochemical and Biophysical Research Communications, 页码:335-339 , 文章类型: Article,,卷期:2010年403-3-4]
- Glutaredoxin-1 (GRX-1) is a cytoplasmic enzyme that highly contributes to the antioxidant defense system. It catalyzes the reversible reduction of glutathione-protein mixed disulfides, a process called deglutathionylatio...
- PIH1D1, a subunit of R2TP complex, inhibits doxorubicin-induced apoptosis
[作者:Inoue, M; Saeki, M; Egusa, H; Niwa, H; Kamisaki, Y,期刊:Biochemical and Biophysical Research Communications, 页码:340-344 , 文章类型: Article,,卷期:2010年403-3-4]
We have previously reported that the two components of R2TP complex, RNA polymerase II-associated protein 3 (RPAP3), and Reptin, regulate apoptosis. Here we characterize another component of the complex, PIH1 domain c...
- Effects of concomitant use of fibroblast growth factor (FGF)-2 with beta-tricalcium phosphate (beta-TCP) on the beagle dog 1-wall periodontal defect model
[作者:Anzai, J; Kitamura, M; Nozaki, T; Nagayasu, T; Terashima, A; Asano, T; Murakami, S,期刊:Biochemical and Biophysical Research Communications, 页码:345-350 , 文章类型: Article,,卷期:2010年403-3-4]
- The effects of concomitant use of fibroblast growth factor-2 (FGF-2) and beta-tricalcium phosphate (beta-TCP) on periodontal regeneration were investigated in the beagle dog 1-wall periodontal defect model. One-wall peri...
- Nano-mechanical properties of living cells expressing constitutively active RhoA effectors
[作者:Tamura, K; Mizutani, T; Haga, H; Kawabata, K,期刊:Biochemical and Biophysical Research Communications, 页码:363-367 , 文章类型: Article,,卷期:2010年403-3-4]
- Filamentous actin and myosin-II are major determinants of cell mechanics and are tightly regulated by a small guanosine triphosphatase, RhoA, and its downstream effectors. We examined the effects of constitutively active...
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