- The tick saliva immunosuppressor, Salp15, contributes to Th17-induced pathology during Experimental Autoimmune Encephalomyelitis
[作者:Juncadella, IJ; Bates, TC; Suleiman, R; Monteagudo-Mera, A; Olson, CM; Navasa, N; Olivera, ER; Osborne, BA; Anguita, J,期刊:Biochemical and Biophysical Research Communications, 页码:105-109 , 文章类型: Article,,卷期:2010年402-1]
- Salp15 is a tick saliva protein that inhibits CD4(+) T cell differentiation through its interaction with CD4. The protein inhibits early signaling events during T cell activation and IL-2 production. Because murine Exper...
- Corepressor MMTR/DMAP1 is an intrinsic negative regulator of CAK kinase to regulate cell cycle progression
[作者:Shin, JH; Kane, HC; Park, YY; Ha, DH; Choi, YH; Eum, HY; Kang, BG; Chae, JH; Shin, I; Lee, JH; Kim, CG,期刊:Biochemical and Biophysical Research Communications, 页码:110-115 , 文章类型: Article,,卷期:2010年402-1]
- We have previously reported that MMTR (MAT1-mediated transcriptional repressor) is a co-repressor that inhibits TFIIH-mediated transcriptional activity via interaction with MAT1 (Kang et al., 2007). Since MAT1 is a membe...
- miR-218 inhibits the invasive ability of glioma cells by direct downregulation of IKK-beta
[作者:Song, LB; Huang, QA; Chen, K; Liu, LP; Lin, CY; Dai, T; Yu, CP; Wu, ZQ; Li, J,期刊:Biochemical and Biophysical Research Communications, 页码:135-140 , 文章类型: Article,,卷期:2010年402-1]
- Aberrant activation of nuclear factor-kappa B (NF-kappa B) pathway has been proven to play important roles in the development and progression of cancers. Activation of NF-kappa B via the classical pathway is modulated by...
- The role of the pro-apoptotic protein Siva in the pathogenesis of Familial Mediterranean fever: A structural and functional analysis
[作者:Goulielmos, GN; Petraki, E; Vassou, D; Eliopoulos, E; Iliopoulos, D; Sidiropoulos, P; Aksentijevich, I; Kardassis, D; Boumpas, DT,期刊:Biochemical and Biophysical Research Communications, 页码:141-146 , 文章类型: Article,,卷期:2010年402-1]
- Familial Mediterranean fever (FMF) is an autosomal, recessive disease, attributed to mutations in MEFV gene encoding pyrin, which is characterized by recurrent, acute and self-limiting attacks of fever as well as an incr...
- Coenzyme A and its thioester pools in fasted and fed rat tissues
[作者:Tokutake, Y; Onizawa, N; Katoh, H; Toyoda, A; Chohnan, S,期刊:Biochemical and Biophysical Research Communications, 页码:158-162 , 文章类型: Article,,卷期:2010年402-1]
- Levels of three coenzyme A (CoA) molecular species, i.e., nonesterified CoA (CoASH), acetyl-CoA, and malonyl-CoA, in fasted and fed rat tissues were analyzed by the acyl-CoA cycling method which makes detection possible ...
- Effect of ethanol on spectral binding, inhibition, and activity of CYP3A4 with an antiretroviral drug nelfinavir
[作者:Kumar, S; Earla, R; Jin, MY; Mitra, AK; Kumar, A,期刊:Biochemical and Biophysical Research Communications, 页码:163-167 , 文章类型: Article,,卷期:2010年402-1]
- Cytochrome P450 3A4 (CYP3A4) is the most abundant CYP enzyme in the liver and metabolizes approximately 50% of the drugs, including anti-retrovirals. Although CYP3A4 induction by ethanol and impact of CYP3A4 on drug meta...
- Functional roles of Cot/Tpl2 in mast cell responses to lipopolysaccharide and Fc epsilon RI-clustering
[作者:Chiba, N; Kakimoto, K; Masuda, A; Matsuguchi, T,期刊:Biochemical and Biophysical Research Communications, 页码:1-6 , 文章类型: Article,,卷期:2010年402-1]
- Cot/Tpl2, a member of MAP kinase kinase kinase (MAPKKK), is indispensable for the ERK activation, as well as the production of TNE-alpha, IL-1 beta, IL-23, and PGE(2) in lipopolysaccharide (LPS)-stimulated macrophages. H...
- High-salt diet advances molecular circadian rhythms in mouse peripheral tissues
[作者:Oike, H; Nagai, K; Fukushima, T; Ishida, N; Kobori, M,期刊:Biochemical and Biophysical Research Communications, 页码:7-13 , 文章类型: Article,,卷期:2010年402-1]
- Dietary compounds influence the expression of various genes and play a major role in changing physiological and metabolic states. However, little is known about the role of food ingredients in the regulation of circadian...
- Knockout of exogenous EGFP gene in porcine somatic cells using zinc-finger nucleases
[作者:Watanabe, M; Umeyama, K; Matsunari, H; Takayanagi, S; Haruyama, E; Nakano, K; Fujiwara, T; Ikezawa, Y; Nakauchi, H; Nagashima, H,期刊:Biochemical and Biophysical Research Communications, 页码:14-18 , 文章类型: Article,,卷期:2010年402-1]
- Zinc-finger nucleases (ZFNs) are expected as a powerful tool for generating gene knockouts in laboratory and domestic animals. Currently, it is unclear whether this technology can be utilized for knocking-out genes in pi...
- Immunological basis of M13 phage vaccine: Regulation under MyD88 and TLR9 signaling
[作者:Hashiguchi, S; Yamaguchi, Y; Takeuchi, O; Akira, S; Sugimura, K,期刊:Biochemical and Biophysical Research Communications, 页码:19-22 , 文章类型: Article,,卷期:2010年402-1]
- Peptide-displaying bacteriophages induce mimotope-specific antibody responses, suggesting a novel application of phage-display library as bacteriophage vaccine. We examined the antibody response against M13 phage in mice...
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