- Molecular characterization, gene expression and transcriptional regulation of cytosolic HSP90 genes in the flatfish Senegalese sole (Solea senegalensis Kaup)
[作者:Manchado, M; Salas-Leiton, E; Infante, C; Ponce, M; Asensio, E; Crespo, A; Zuasti, E; Canavate, JP,期刊:Gene, 页码:77-84 , 文章类型: Article,,卷期:2008年416-1-2]
- HSP90 proteins are chaperones that play a pivotal role in controlling multiple regulatory pathways such as stress defense, hormone signalling, cell cycle control, cell proliferation and differentiation, and apoptosis. In...
- Analysis of the Runx2 promoter in osseous and non-osseous cells and identification of HIF2A as a potent transcription activator
[作者:Tamiya, H; Ikeda, T; Jeong, JH; Saito, T; Yano, F; Jung, YK; Ohba, S; Kawaguchi, H; Chung, UI; Choi, JY,期刊:Gene, 页码:53-60 , 文章类型: Article,,卷期:2008年416-1-2]
- Little is known about the upstream regulator of Runx2, a master regulator of osteoblast differentiation in bone tissues. To elucidate the molecular mechanism of Runx2 gene expression, we analyzed Runx2 promoter activity ...
- Cloning and functional characterization of the ovine Hormone Sensitive Lipase (HSL) full-length cDNAs: An integrated approach
[作者:Lampidonis, AD; Argyrokastritis, A; Stravopodis, DJ; Voutsinas, GE; Ntouroupi, TG; Margaritis, LH; Bizelis, I; Rogdakis, E,期刊:Gene, 页码:30-43 , 文章类型: Article,,卷期:2008年416-1-2]
- Hormone Sensitive Lipase (HSL) is a highly regulated enzyme that mediates lipolysis in adipocytes. HSL enzymatic activity is increased by adrenergic agonists, such as catecholamines and glucagons, which induce cyclic AMP...
- Molecular cloning and structural organization of the gene encoding the mouse lysosomal di-N-acetylchitobiase (ctbs)
[作者:Balducci, C; Bibi, L; Berg, T; Persichetti, E; Tiribuzi, R; Martino, S; Paciotti, S; Roberti, R; Orlacchio, A; Beccari, T,期刊:Gene, 页码:85-91 , 文章类型: Article,,卷期:2008年416-1-2]
- The lysosomal enzyme di-N-acetylchitobiase hydrolyzes N-acetylglucosamine from the reducing-end of the N,N' diacetylchitobiose core of N-linked-oligosaccharides. The presence of chitobiase in the tissues of different spe...
- Questionable 16S ribosomal RNA gene annotations are frequent in completed microbial genomes
[作者:Lin, YH; Chang, BCH; Chiang, PW; Tang, SL,期刊:Gene, 页码:44-47 , 文章类型: Article,,卷期:2008年416-1-2]
- According to recent reports, many ribosomal RNA gene annotations are still questionable, and the use of inappropriate tools for annotation has been blamed. However, we believe that the abundant 16S rRNA partial sequence ...
- Phylogenetic information from three mitochondrial genomes of Terebelliformia (Annelida) worms and duplication of the methionine tRNA
[作者:Zhong, M; Struck, TH; Halanych, KM,期刊:Gene, 页码:11-21 , 文章类型: Article,,卷期:2008年416-1-2]
- Mitochondrial genomes have been useful for inferring animal phylogeny across a wide range of clades, however they are still poorly sampled in some animal taxa, limiting our knowledge of mtDNA evolution. For example, desp...
- Molecular properties of the putative autolysin AtIWM encoded by Staphylococcus warneri M: Mutational and biochemical analyses of the amidase and glucosaminidase domains
[作者:Yokoi, KJ; Sugahara, K; Iguchi, A; Nishitani, G; Ikeda, M; Shimada, T; Inagaki, N; Yamakawa, A; Taketo, A; Kodaira, KI,期刊:Gene, 页码:66-76 , 文章类型: Article,,卷期:2008年416-1-2]
- The putative autolysin AtIWM of Staphylococcus warneri M is a modular protein exhibiting two enzyme activities, an N-terminal side amidase (ami(atIwm)-R1-R2) and a C-terminal side glucosaminidase (R3-glu(atIwm)). Zymogra...
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