- Astrocyte elevated gene-1 is a proliferation promoter in breast cancer via suppressing transcriptional factor FOXO1
[作者:Li, J; Yang, L; Song, L; Xiong, H; Wang, L; Yan, X; Yuan, J; Wu, J; Li, M,期刊:Oncogene, 页码:3188-3196 , 文章类型: Article,,卷期:2009年28-36]
- We have previously reported that astrocyte elevated gene-1 (AEG-1) was upregulated in human breast cancer. However, the biological function of AEG-1 in the development and progression of breast cancer remains to be clari...
- Autonomous regulation of osteosarcoma cell invasiveness by Wnt5a/Ror2 signaling
[作者:Enomoto, M; Hayakawa, S; Itsukushima, S; Ren, DY; Matsuo, M; Tamada, K; Oneyama, C; Okada, M; Takumi, T; Nishita, M; Minami, Y,期刊:Oncogene, 页码:3197-3208 , 文章类型: Article,,卷期:2009年28-36]
- The receptor tyrosine kinase Ror2 regulates cell migration by acting as a receptor or co-receptor for Wnt5a. Although Wnt5a has been implicated in the invasiveness of several types of tumors, the role of Ror2 in tumor in...
- Lithium suppresses motility and invasivity of v-src-transformed cells by glutathione-dependent activation of phosphotyrosine phosphatases
[作者:Neel, BD; Lopez, J; Chabadel, A; Gillet, G,期刊:Oncogene, 页码:3246-3260 , 文章类型: Article,,卷期:2009年28-36]
- Lithium has long been used for the treatment and prophylaxis of bipolar mood disorder. However, nerve cells are not the sole targets of lithium. Indeed, lithium was reported to target numerous cell types, and affect cell...
- Accelerated mammary maturation and differentiation, and delayed MMTVneu-induced tumorigenesis of K303R mutant ER alpha transgenic mice
[作者:Herynk, MH; Lewis, MT; Hopp, TA; Medina, D; Corona-Rodriguez, A; Cui, Y; Beyer, AR; Fuqua, SAW,期刊:Oncogene, 页码:3177-3187 , 文章类型: Article,,卷期:2009年28-36]
- We identified a somatic mutation in estrogen receptor-alpha (ER alpha) in breast cancer causing a lysine to arginine transition (K303R) resulting in hypersensitivity to estrogen, altered associations with coactivators an...
- Nucleophosmin protein expression level, but not threonine 198 phosphorylation, is essential in growth and proliferation
[作者:Brady, SN; Maggi, LB; Winkeler, CL; Toso, EA; Gwinn, AS; Pelletier, CL; Weber, JD,期刊:Oncogene, 页码:3209-3220 , 文章类型: Article,,卷期:2009年28-36]
- Nucleophosmin (NPM), an oligomeric phosphoprotein and nucleolar target of the ARF tumor suppressor, contributes to several critical cellular processes. Previous studies have shown that the human NPM's phosphorylation by ...
- Involvement of mitochondria and recruitment of Fas/CD95 signaling in lipid rafts in resveratrol-mediated antimyeloma and antileukemia actions
[作者:Reis-Sobreiro, M; Gajate, C; Mollinedo, F,期刊:Oncogene, 页码:3221-3234 , 文章类型: Article,,卷期:2009年28-36]
- We have found that resveratrol (trans-3,4',5-trihydroxystilbene) induced apoptosis in multiple myeloma (MM) and T-cell leukemia cells through coclustering of Fas/CD95 death receptor and lipid rafts, whereas normal lympho...
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