- 17 beta-Estradiol attenuates saturated fatty acid diet-induced liver injury in ovariectomized mice by up-regulating hepatic senescence marker protein-30
[作者:Fukui, M; Senmaru, T; Hasegawa, G; Yamazaki, M; Asano, M; Kagami, Y; Ishigami, A; Maruyama, N; Iwasa, K; Kitawaki, J; Itoh, Y; Okanoue, T; Ohta, M; Obayashi, H; Nakamura, N,期刊:Biochemical and Biophysical Research Communications, 页码:252-257 , 文章类型: Article,,卷期:2011年415-2]
- Senescence marker protein-30 (SMP30) plays an important role in intracellular Ca(2+) homeostasis. The aim of the present study was to investigate the effects of estrogens on liver apoptotic damage and changes in SMP30 ex...
- The hsa-miR-5739 modulates the endoglin network in endothelial cells derived from human embryonic stem cells
[作者:Yoo, JK; Kim, J; Choi, SJ; Kim, CH; Lee, DR; Chung, HM; Kim, JK,期刊:Biochemical and Biophysical Research Communications, 页码:258-262 , 文章类型: Article,,卷期:2011年415-2]
- MicroRNAs are small, noncoding RNAs that bind to seed sequences on the 3' untranslated regions of their target genes and then negatively regulate gene expressions via the RISC complex. The novel miRNA, hsa-miR-5739, was ...
- Proteomic identification of dysferlin-interacting protein complexes in human vascular endothelium
[作者:Leung, C; Utokaparch, S; Sharma, A; Yu, C; Abraham, T; Borchers, C; Bernatchez, P,期刊:Biochemical and Biophysical Research Communications, 页码:263-269 , 文章类型: Article,,卷期:2011年415-2]
- Dysferlin is a membrane-anchored protein known to facilitate membrane repair in skeletal muscles following mechanical injury. Mutations of dysferlin gene impair sarcolemma integrity, a hallmark of certain forms of muscul...
- Protein tyrosine phosphatase CD45 as a molecular biosensor of hydrogen peroxide generation in cell culture media
[作者:Kuban-Jankowska, A; Knap, N; Gorska, M; Popowska, U; Wozniak, M,期刊:Biochemical and Biophysical Research Communications, 页码:270-273 , 文章类型: Article,,卷期:2011年415-2]
- We have designed a useful method of assessing reactive oxygen species generation in biological fluids. The novel assay utilizes tyrosine phosphatase CD45 as a biosensor of oxidative stress. Applying this new method, we e...
- Proteasome inhibitors improve the function of mutant lysosomal alpha-glucosidase in fibroblasts from Pompe disease patient carrying c.546G > T mutation
[作者:Shimada, Y; Nishida, H; Nishiyama, Y; Kobayashi, H; Higuchi, T; Eto, Y; Ida, H; Ohashi, T,期刊:Biochemical and Biophysical Research Communications, 页码:274-278 , 文章类型: Article,,卷期:2011年415-2]
- Pompe disease (glycogen storage disease type II) is an autosomal recessive myopathic disorder arising from the deficiency of lysosomal acid a-glucosidase (GAA). Recently, we found that mutant GAA in patient fibroblasts c...
- Genetic analysis of IREB2, FAM13A and XRCC5 variants in Chinese Han patients with chronic obstructive pulmonary disease
[作者:Guo, Y; Lin, H; Gao, K; Xu, HB; Deng, X; Zhang, Q; Luo, Z; Sun, S; Deng, H,期刊:Biochemical and Biophysical Research Communications, 页码:284-287 , 文章类型: Article,,卷期:2011年415-2]
- Recently, variants (rs2568494, rs2869967 and rs3821104) in the IREB2, FAM13A and XRCC5 genes were found to be associated with chronic obstructive pulmonary disease (COPD) in non-Asian populations by genome-wide associati...
- Acidosis leads to neurological disorders through overexciting cortical pyramidal neurons
[作者:Zhao, H; Cai, Y; Yang, ZC; He, DD; Shen, BZ,期刊:Biochemical and Biophysical Research Communications, 页码:224-228 , 文章类型: Article,,卷期:2011年415-2]
- The patients suffering from acidosis usually sign psychological deficits. The cerebral dysfunction is reportedly caused by an acid-induced functional impairment of GABAergic neurons; however, the role of pyramidal neuron...
- Monitoring succinyl-CoA:3-oxoacid CoA transferase using monoclonal antibodies nitration in mitochondria
[作者:Sun, HD; He, JX; Ru, YW; Yin, SY; Xie, YY; Yin, L; Wei, HF; Wu, L; Liu, SQ,期刊:Biochemical and Biophysical Research Communications, 页码:239-244 , 文章类型: Article,,卷期:2011年415-2]
- Two tyrosine residues (Tyr(4) and Tyr(76)) of succinyl-CoA:3-oxoacid CoA transferase (SCOT) are sensitive to nitric oxide (NO) stress, as assessed by mass spectrometry and site-direct mutagenesis. However, monitoring the...
- Oct4-related cytokine effects regulate tumorigenic properties of colorectal cancer cells
[作者:Chang, CJ; Chien, Y; Lu, KH; Chang, SC; Chou, YC; Huang, CS; Chang, CH; Chen, KH; Chang, YL; Tseng, LM; Song, WS; Wang, JJ; Lin, JK; Huang, PI; Lan, YT,期刊:Biochemical and Biophysical Research Communications, 页码:245-251 , 文章类型: Article,,卷期:2011年415-2]
- Oct4, a member of the POU-domain transcription factor family, has been implicated in the cancer stem cell (CSC)-like properties of various cancers. However, the precise role of Oct4 in colorectal CSC initiation remains u...
- Lentivirus-ABCG1 instillation reduces lipid accumulation and improves lung compliance in GM-CSF knock-out mice
[作者:Malur, A; Huizar, I; Wells, G; Barna, BP; Malur, AG; Thomassen, MJ,期刊:Biochemical and Biophysical Research Communications, 页码:288-293 , 文章类型: Article,,卷期:2011年415-2]
- We have shown decreased expression of the nuclear transcription factor, peroxisome proliferator-activated receptor-gamma (PPAR gamma) and the PPAR gamma-regulated ATP-binding cassette transporter Cl (ABCG1) in alveolar m...
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