- Neutron Structure of Human Carbonic Anhydrase II: A Hydrogen-Bonded Water Network "Switch" Is Observed between pH 7.8 and 10.0
[作者：Fisher, Z; Kovalevsky, AY; Mustyakimov, M; Silverman, DN; McKenna, R; Langan, P,期刊：Biochemistry, 页码：9421-9423 , 文章类型： Article，,卷期：2011年50-44]
- The neutron structure of wild-type human carbonic anhydrase II at pH 7.8 has been determined to 2.0 angstrom resolution. Detailed analysis and comparison to the previously determined structure at pH 10.0 show important d...
- Pseudohyperphosphorylation Has Differential Effects on Polymerization and Function of Tau Isoforms
[作者：Combs, B; Voss, K; Gamblin, TC,期刊：Biochemistry, 页码：9446-9456 , 文章类型： Article，,卷期：2011年50-44]
- The microtubule-associated protein tau exists as six isoforms created through the splicing of the second, third, and tenth exons. The isoforms are classified by their number of N-terminal exons (ON, IN, or 2N) and by the...
- Protein Conformational Changes of the Oxidative Stress Sensor, SoxR, upon Redox Changes of the [2Fe-2S] Cluster Probed with Ultraviolet Resonance Raman Spectroscopy
[作者：Kobayashi, K; Mizuno, M; Fujikawa, M; Mizutani, Y,期刊：Biochemistry, 页码：9468-9474 , 文章类型： Article，,卷期：2011年50-44]
- The [2Fe-2S] transcription factor, SoxR, a member of the MerR family, functions as a bacterial sensor of oxidative stress in Escherichia coli. SoxR is activated by reversible one-electron oxidation of the [2Fe-2S] cluste...
- Functional Consequences of the Creation of an Asp-His-Fe Triad in a 3/3 Globin
[作者：D'Antonio, EL; D'Antonio, J; de Serrano, V; Gracz, H; Thompson, MK; Ghiladi, RA; Bowden, EF; Franzen, S,期刊：Biochemistry, 页码：9664-9680 , 文章类型： Article，,卷期：2011年50-44]
- The proximal side of dehaloperoxidase-hemoglobin A (DHP A) from Amphitrite ornata has been modified via site-directed mutagenesis of methionine 86 into aspartate (M86D) to introduce an Asp-His-Fe triad charge relay. X-ra...
- Mammalian Sialyltransferase ST3Gal-II: Its Exchange Sialylation Catalytic Properties Allow Labeling of Sialyl Residues in Mucin-Type Sialylated Glycoproteins and Specific Gangliosides
[作者：Chandrasekaran, EV; Xue, J; Xia, J; Locke, RD; Patil, SA; Neelamegham, S; Matta, KL,期刊：Biochemistry, 页码：9475-9487 , 文章类型： Article，,卷期：2011年50-44]
- While glycosyltransferases are known to display unidirectional enzymatic activity, recent studies suggest that some can also catalyze readily reversible reactions. Recently, we found that mammalian sialyltransferase ST3G...
- Examining Docking Interactions on ERK2 with Modular Peptide Substrates
[作者：Lee, S; Warthaka, M; Yan, CL; Kaoud, TS; Ren, PY; Dalby, KN,期刊：Biochemistry, 页码：9500-9510 , 文章类型： Article，,卷期：2011年50-44]
- ERK2 primarily recognizes substrates through two recruitment sites, which lie outside the active site cleft of the kinase. These recruitment sites bind modular-docking sequences called docking sites and are potentially a...
- Retinal Degeneration 3 (RD3) Protein Inhibits Catalytic Activity of Retinal Membrane Guanylyl Cyclase (RetGC) and Its Stimulation by Activating Proteins
[作者：Peshenko, IV; Olshevskaya, EV; Azadi, S; Molday, LL; Molday, RS; Dizhoor, AM,期刊：Biochemistry, 页码：9511-9519 , 文章类型： Article，,卷期：2011年50-44]
- Retinal membrane guanylyl cyclase (RetGC) in the outer segments of vertebrate photoreceptors is controlled by guanylyl cyclase activating proteins (GCAPs), responding to light-dependent changes of the intracellular Ca(2+...
- Mechanism of the Intramolecular Claisen Condensation Reaction Catalyzed by MenB, a Crotonase Superfamily Member
[作者：Li, HJ; Li, XK; Liu, NN; Zhang, HN; Truglio, JJ; Mishra, S; Kisker, C; Garcia-Diaz, M; Tonge, PJ,期刊：Biochemistry, 页码：9532-9544 , 文章类型： Article，,卷期：2011年50-44]
- MenB, the 1,4-dihydroxy-2-naphthoyl-CoA synthase from the bacterial menaquinone biosynthesis pathway, catalyzes an intramolecular Claisen condensation (Dieckmann reaction) in which the electrophile is an unactivated carb...
- A Reduced-Amide Inhibitor of Pin1 Binds in a Conformation Resembling a Twisted-Amide Transition State
[作者：Xu, GYG; Zhang, Y; Mercedes-Camacho, AY; Etzkorn, FA,期刊：Biochemistry, 页码：9545-9550 , 文章类型： Article，,卷期：2011年50-44]
- The mechanism of the cell cycle regulatory peptidyl prolyl isomerase (PPIase), Pin1, was investigated using reduced-amide inhibitors designed to mimic the twisted-amide transition state. Inhibitors, R-pSer-Psi[CH(2)N]-Pr...
- Three-Dimensional Structure of Mannosyl-3-phosphoglycerate Phosphatase from Thermus thermophilus HB27: A New Member of the Haloalcanoic Acid Dehalogenase Superfamily
[作者：Goncalves, S; Esteves, AM; Santos, H; Borges, N; Matias, PM,期刊：Biochemistry, 页码：9551-9567 , 文章类型： Article，,卷期：2011年50-44]
- Mannosyl-3-phosphoglycerate phosphatase (MpgP) is a key mediator in the physiological response to thermal and osmotic stresses, catalyzing the hydrolysis of mannosyl-3-phosphoglycerate (MPG) to the final product, a-manno...
- Zn(2+)-Induced Rearrangement of the Disordered TPPP/p25 Affects Its Microtubule Assembly and GTPase Activity
[作者：Zotter, A; Olah, J; Hlavanda, E; Bodor, A; Perczel, A; Szigeti, K; Fidy, J; Ovadi, J,期刊：Biochemistry, 页码：9568-9578 , 文章类型： Article，,卷期：2011年50-44]
- Tubulin polymerization promoting protein/p25 (TPPP/p25) modulates the dynamics and stability of the microtubule system and plays crucial role in the myelination of oligodendrocytes. Here we showed by CD, fluorescence, an...
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