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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共26条记录   Dephosphorylation of the Core Clock Protein KaiC in the Cyanobacterial KaiABC Circadian Oscillator Proceeds via an ATP Synthase Mechanism [作者：Egli, M; Mori, T; Pattanayek, R; Xu, Y; Qin, XM; Johnson, CH,期刊：Biochemistry, 页码：1547-1558 , 文章类型： Article，,卷期：2012年51-8] The circadian clock of the cyanobacterium Synechococcus elongatus can be reconstituted in vitro from three proteins, KaiA, KaiB, and KaiC in the presence of ATP, to tick in a temperature-compensated manner. KaiC, the cen... Molecular Dynamics Simulations of the TrkH Membrane Protein [作者：Domene, C; Furini, S,期刊：Biochemistry, 页码：1559-1565 , 文章类型： Article，,卷期：2012年51-8] TrkH is a transmembrane protein that mediates uptake of K+ through the cell membrane. Despite the recent determination of its crystallographic structure, the nature of the permeation mechanism is still unknown, that is, ... Stem-Forming Regions That Are Essential for the Amyloidogenesis of Prion Proteins [作者：Saiki, M; Hidaka, Y; Nara, M; Morii, H,期刊：Biochemistry, 页码：1566-1576 , 文章类型： Article，,卷期：2012年51-8] Prion diseases represent fatal neurodegenerative disorders caused by the aggregation of prion proteins. With regard to the formation of the amyloidogenic cross-beta-structure, the initial mechanism in the conversion to a... Sided Functions of an Arginine-Agmatine Antiporter Oriented in Liposomes [作者：Tsai, MF; Fang, YL; Miler, C,期刊：Biochemistry, 页码：1577-1585 , 文章类型： Article，,卷期：2012年51-8] The arginine-dependent extreme acid resistance system helps enteric bacteria survive the harsh gastric environment. At the center of this multiprotein system is an arginine-agmatine antiporter, AdiC. To maintain cytoplas... Role of Calcium in Metalloenzymes: Effects of Calcium Removal on the Axial Ligation Geometry and Magnetic Properties of the Catalytic Diheme Center in MauG [作者：Chen, Y; Naik, SG; Krzystek, J; Shin, S; Nelson, WH; Xue, SH; Yang, JJ; Davidson, VL; Liu, AM,期刊：Biochemistry, 页码：1586-1597 , 文章类型： Article，,卷期：2012年51-8] MauG is a diheme enzyme possessing a five-coordinate high-spin heme with an axial His ligand and a six-coordinate low-spin heme with His-Tyr axial ligation. A Ca2+ ion is linked to the two hemes via hydrogen bond network... Proline 107 Is a Major Determinant in Maintaining the Structure of the Distal Pocket and Reactivity of the High-Spin Heme of MauG [作者：Feng, ML; Jensen, LMR; Yukl, ET; Wei, XX; Liu, AM; Wilmot, CM; Davidson, VL,期刊：Biochemistry, 页码：1598-1606 , 文章类型： Article，,卷期：2012年51-8] The diheme enzyme MauG catalyzes a six-electron oxidation required for posttranslational modification of a precursor of methylamine dehydrogenase (preMADH) to complete the biosynthesis of its protein-derived tryptophan t... O-2-Evolving Chlorite Dismutase as a Tool for Studying O-2-Utilizing Enzymes [作者：Dassama, LMK; Yosca, TH; Conner, DA; Lee, MH; Blanc, B; Streit, BR; Green, MT; DuBois, JL; Krebs, C; Bollinger, JM,期刊：Biochemistry, 页码：1607-1616 , 文章类型： Article，,卷期：2012年51-8] The direct interrogation of fleeting intermediates by rapid-mixing kinetic methods has significantly advanced our understanding of enzymes that utilize dioxygen. The gas's modest aqueous solubility (<2 mM at 1 atm) prese... Comparative Analysis of Cone and Rod Transducins Using Chimeric G alpha Subunits [作者：Gopalakrishna, KN; Boyd, KK; Artemyev, NO,期刊：Biochemistry, 页码：1617-1624 , 文章类型： Article，,卷期：2012年51-8] The molecular nature of transducin-alpha subunits (G alpha(t)) may contribute to the distinct physiology of cone and rod photoreceptors. Biochemical properties of mammalian cone G alpha(t2) subunits and their differences... Imaging of Protein Crystals with Two-Photon Microscopy [作者：Padayatti, P; Palczewska, G; Sun, WY; Palczewski, K; Salom, D,期刊：Biochemistry, 页码：1625-1637 , 文章类型： Article，,卷期：2012年51-8] Second-order nonlinear optical imaging of chiral crystals (SONICC), which portrays second-harmonic generation (SHG) by noncentrosymmetric crystals, is emerging as a powerful imaging technique for protein crystals in medi... Assembly of Membrane-Bound Protein Complexes: Detection and Analysis by Single Molecule Diffusion [作者：Ziemba, BP; Knight, JD; Falke, JJ,期刊：Biochemistry, 页码：1638-1647 , 文章类型： Article，,卷期：2012年51-8] Protein complexes assembled on membrane surfaces regulate a wide array of signaling pathways and cell processes. Thus, a molecular understanding of the membrane surface diffusion and regulatory events leading to the asse... Characterization of HmqF, a Protein Involved in the Biosynthesis of Unsaturated Quinolones Produced by Burkholderia thailandensis [作者：Agarwal, A; Kahyaoglu, C; Hansen, DB,期刊：Biochemistry, 页码：1648-1657 , 文章类型： Article，,卷期：2012年51-8] The opportunistic pathogen Burkholderia thailandensis produces a number of structurally similar unsaturated quinolones involved in quorum sensing. However, little is known about the biosynthesis of these unsaturated quin... Improving upon Nature: Active Site Remodeling Produces Highly Efficient Aldolase Activity toward Hydrophobic Electrophilic Substrates [作者：Cheriyan, M; Toone, EJ; Fierke, CA,期刊：Biochemistry, 页码：1658-1668 , 文章类型： Article，,卷期：2012年51-8] The substrate specificity of enzymes is frequently narrow and constrained by multiple interactions, limiting the use of natural enzymes in biocatalytic applications. Aldolases have important synthetic applications, but t... Two Translation Products of Yersinia yscQ Assemble To Form a Complex Essential to Type III Secretion [作者：Bzymek, KP; Hamaoka, BY; Ghosh, P,期刊：Biochemistry, 页码：1669-1677 , 文章类型： Article，,卷期：2012年51-8] The bacterial flagellar C-ring is composed of two essential proteins, FliM and FliN. The smaller protein, FliN, is similar to the C-terminus of the larger protein, FliM, both being composed of SpoA domains. While bacteri... Conserved Signal Peptide Recognition Systems across the Prokaryotic Domains [作者：Coulthurst, SJ; Dawson, A; Hunter, WN; Sargent, F,期刊：Biochemistry, 页码：1678-1686 , 文章类型： Article，,卷期：2012年51-8] The twin-arginine translocation (Tat) pathway is a protein targeting system found in bacteria, archaea, and chloroplasts. Proteins are directed to the Tat translocase by N-terminal signal peptides containing SRRxFLK "twi... Human Glutaredoxin 3 Forms [2Fe-2S]-Bridged Complexes with Human BolA2 [作者：Li, HR; Mapolelo, DT; Randeniya, S; Johnson, MK; Outten, CE,期刊：Biochemistry, 页码：1687-1696 , 文章类型： Article，,卷期：2012年51-8] Human glutaredoxin 3 (Glrx3) is an essential [2Fe-2S]-binding protein with ill-defined roles in immune cell response, embryogenesis, cancer cell growth, and regulation of cardiac hypertrophy. Similar to other members of ... Rapid Exchange of Metal between Zn-7-Metallothionein-3 and Amyloid-beta Peptide Promotes Amyloid-Related Structural Changes [作者：Pedersen, JT; Hureau, C; Hemmingsen, L; Heegaard, NHH; Ostergaard, J; Vasak, M; Faller, P,期刊：Biochemistry, 页码：1697-1706 , 文章类型： Article，,卷期：2012年51-8] Metal ions, especially Zn2+ and Cu2+, are implemented in the neuropathogenesis of Alzheimer's disease (AD) by modulating the aggregation of amyloid-beta peptides (A beta). Also, Cu2+ may promote AD) neurotoxicity through...