- Small-Molecule Suppressors of Cytokine-Induced beta-Cell Apoptosis
[作者:CHOU DANNY HUNGCHIEH; BODYCOMBE NICOLE E; CARRINSKI HYMAN A; LEWIS TIMOTHY A; CLEMONS PAUL A; SCHREIBER STUART L; WAGNER BRIDGET K,期刊:ACS CHEMICAL BIOLOGY, 页码:729-734 , 文章类型: Article,,卷期:2010年5-8]
- Pancreatic beta-cell apoptosis is a critical event during the development of type-1 diabetes. The identification of small molecules capable of preventing cytokine-induced apoptosis could lead to avenues for therapeutic i...
- ANS Binding Reveals Common Features of Cytotoxic Amyloid Species
[作者:BOLOGNESI BENEDETTA; KUMITA JANET R; BARROS TERESA P; ESBJORNER ELIN K; LUHESHI LEILA M; CROWTHER DAMIAN C; WILSON MARK R; DOBSON CHRISTOPHER M; FAVRIN GIORGIO; YERBURY JUSTIN J,期刊:ACS CHEMICAL BIOLOGY, 页码:735-740 , 文章类型: Article,,卷期:2010年5-8]
- Oligomeric assemblies formed from a variety of disease-associated peptides and proteins have been strongly associated with toxicity in many neurodegenerative conditions, such as Alzheimer's disease. The precise nature of...
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