- Acceptable HLA-mismatching in unrelated donor bone marrow transplantation for patients with acquired severe aplastic anemia
[作者：Yagasaki, H; Kojima, S; Yabe, H; Kato, K; Kigasawa, H; Sakamaki, H; Tsuchida, M; Kato, S; Kawase, T; Morishima, Y; Kodera, Y,期刊：Blood, 页码：3186-3190 , 文章类型： Article，,卷期：2011年118-11]
- We retrospectively analyzed the effect of HLA mismatching (HLA-A, -B, -C, -DRB1, -DQB1) with molecular typing on transplantation outcome for 301 patients with acquired severe aplastic anemia (SAA) who received an unrelat...
- Accumulation of oxidative DNA damage restricts the self-renewal capacity of human hematopoietic stem cells
[作者：Yahata, T; Takanashi, T; Muguruma, Y; Ibrahim, A; Matsuzawa, H; Uno, T; Sheng, Y; Onizuka, M; Ito, M; Kato, S; Ando, K,期刊：Blood, 页码：2941-2950 , 文章类型： Article，,卷期：2011年118-11]
- Stem cells of highly regenerative organs including blood are susceptible to endogenous DNA damage caused by both intrinsic and extrinsic stress. Response mechanisms to such stress equipped in hematopoietic stem cells (HS...
- Next-generation leukemia immunotherapy
[作者：Vincent, K; Roy, DC; Perreault, C,期刊：Blood, 页码：2951-2959 , 文章类型： Article，,卷期：2011年118-11]
- Allogeneic hematopoietic cell transplantation led to the discovery of the allogeneic GVL effect, which remains the most convincing evidence that immune cells can cure cancer in humans. However, despite its great paradigm...
- MicroRNA function in myeloid biology
[作者：O'Connell, RM; Zhao, JL; Rao, DS,期刊：Blood, 页码：2960-2969 , 文章类型： Review，,卷期：2011年118-11]
- The past 5 years have seen an explosion of knowledge about miRNAs and their roles in hematopoiesis, cancer, and other diseases. In myeloid development, there is a growing appreciation for both the importance of particula...
- Pomalidomide plus low-dose dexamethasone in myeloma refractory to both bortezomib and lenalidomide: comparison of 2 dosing strategies in dual-refractory disease
[作者：Lacy, MQ; Allred, JB; Gertz, MA; Hayman, SR; Short, KD; Buadi, F; Dispenzieri, A; Kumar, S; Greipp, PR; Lust, JA; Russell, SJ; Dingli, D; Zeldenrust, S; Fonseca, R; Bergsagel, PL; Roy, V; Stewart, AK; Laumann, K; Mandrekar, SJ; Reeder, C; Rajkumar, SV; Mikhael, JR,期刊：Blood, 页码：2970-2975 , 文章类型： Article，,卷期：2011年118-11]
- Pomalidomide at doses of 2 or 4 mg/d has demonstrated excellent activity in patients with multiple myeloma (MM). We opened 2 sequential phase 2 trials using the pomalidomide with weekly dexamethasone (Pom/dex) regimen at...
- Follicular lymphoma in situ: clinical implications and comparisons with partial involvement by follicular lymphoma
[作者：Jegalian, AG; Eberle, FC; Pack, SD; Mirvis, M; Raffeld, M; Pittaluga, S; Jaffe, ES,期刊：Blood, 页码：2976-2984 , 文章类型： Article，,卷期：2011年118-11]
- Follicular lymphoma in situ (FLIS) was first described nearly a decade ago, but its clinical significance remains uncertain. We reevaluated our original series and more recently diagnosed cases to develop criteria for th...
- Incidence, clinical course, and prognosis of secondary monoclonal gammopathy of undetermined significance in patients with multiple myeloma
[作者：Wadhera, RK; Kyle, RA; Larson, DR; Dispenzieri, A; Kumar, S; Lazarus, HM; Rajkumar, SV,期刊：Blood, 页码：2985-2987 , 文章类型： Article，,卷期：2011年118-11]
- During the course of multiple myeloma (MM), new monoclonal proteins of an isotype distinct from the original clone, referred to as secondary monoclonal gammopathy of undetermined significance (MGUS), have been described....
- IL-17-producing invariant NKT cells in lymphoid organs are recent thymic emigrants identified by neuropilin-1 expression
[作者：Milpied, P; Massot, B; Renand, A; Diem, S; Herbelin, A; Leite-de-Moraes, M; Rubio, MT; Hermine, O,期刊：Blood, 页码：2993-3002 , 文章类型： Article，,卷期：2011年118-11]
- Despite increasing knowledge on the mechanisms of invariant natural killer T (iNKT)-cell development in the thymus, the function of recent thymic emigrant (RTE) iNKT cells remains largely unexplored, principally because ...
- Monoclonal antibody blockade of IL-2 receptor alpha during lymphopenia selectively depletes regulatory T cells in mice and humans
[作者：Mitchell, DA; Cui, XY; Schmittling, RJ; Sanchez-Perez, L; Snyder, DJ; Congdon, KL; Archer, GE; Desjardins, A; Friedman, AH; Friedman, HS; Herndon, JE; McLendon, RE; Reardon, DA; Vredenburgh, JJ; Bigner, DD; Sampson, JH,期刊：Blood, 页码：3003-3012 , 文章类型： Article，,卷期：2011年118-11]
- Lymphodepletion augments adoptive cell transfer during antitumor immunotherapy, producing dramatic clinical responses in patients with malignant melanoma. We report that the lymphopenia induced by the chemotherapeutic ag...
- The mismatch repair pathway functions normally at a non-AID target in germinal center B cells
[作者：Green, B; Belcheva, A; Nepal, RM; Boulianne, B; Martin, A,期刊：Blood, 页码：3013-3018 , 文章类型： Article，,卷期：2011年118-11]
- Deficiency in Msh2, a component of the mismatch repair (MMR) system, leads to an approximately 10-fold increase in the mutation frequency in most tissues. By contrast, Msh2 deficiency in germinal center (GC) B cells decr...
- Complex regulation of human NKG2D-DAP10 cell surface expression: opposing roles of the gamma(c) cytokines and TGF-beta 1
[作者：Park, YP; Choi, SC; Kiesler, P; Gil-Krzewska, A; Borrego, F; Weck, J; Krzewski, K; Coligan, JE,期刊：Blood, 页码：3019-3027 , 文章类型： Article，,卷期：2011年118-11]
- Natural killer (NK) cells help protect the host against viral infections and tumors. NKG2D is a vital activating receptor, also expressed on subsets of T cells, whose ligands are up-regulated by cells in stress. Ligation...
- Acquired genomic copy number aberrations and survival in chronic lymphocytic leukemia
[作者：Ouillette, P; Collins, R; Shakhan, S; Li, JH; Peres, E; Kujawski, L; Talpaz, M; Kaminski, M; Li, C; Shedden, K; Malek, SN,期刊：Blood, 页码：3051-3061 , 文章类型： Article，,卷期：2011年118-11]
- Genomic aberrations are of predominant importance to the biology and clinical outcome of patients with chronic lymphocytic leukemia (CLL), and FISH-based genomic risk classifications are routinely used in clinical decisi...
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