- Thailandepsins: Bacterial Products with Potent Histone Deacetylase Inhibitory Activities and Broad-Spectrum Antiproliferative Activities
[作者:Wang, C; Henkes, LM; Doughty, LB; He, M; Wang, DF; Meyer-Almes, FJ; Cheng, YQ,期刊:Journal of natural products, 页码:2031-2038 , 文章类型: Article,,卷期:2011年74-10]
- Histone deacetylase (HDAC) inhibitors have emerged as a new class of anticancer drugs, with one synthetic compound, SAHA (vorinostat, Zolinza; 1), and one natural product, FK228 (depsipeptide, romidepsin, Istodax; 2), ap...
- Ganodone, a Bioactive Benzofuran from the Fruiting Bodies of Ganoderma tsugae
[作者:La Clair, JJ; Rheingold, AL; Burkart, MD,期刊:Journal of natural products, 页码:2045-2051 , 文章类型: Article,,卷期:2011年74-10]
- Extracts of Ganoderma tsugae, also known as the Hemlock varnish shelf mushroom, and related Reishi mushrooms are well documented in traditional Chinese medicine. Several Ganoderma sp. are currently cultivated for use in ...
- Smardaesidins A-G, Isopimarane and 20-nor-Isopimarane Diterpenoids from Smardaea sp., a Fungal Endophyte of the Moss Ceratodon purpureus
[作者:Wang, XN; Bashyal, BP; Wijeratne, EMK; U'Ren, JM; Liu, MX; Gunatilaka, MK; Arnold, AE; Gunatilaka, AAL,期刊:Journal of natural products, 页码:2052-2061 , 文章类型: Article,,卷期:2011年74-10]
- Five new isopimarane diterpenes, smardaesidins A E (1 5) and two new 20-nor-isopirnarane diterpenes, smardaesidins F (6) and G (7), together with sphaeropsidins A (8) and C F (10-13) were isolated from an endophytic fung...
- Antinociceptive Properties of Bergenin
[作者:de Oliveira, CM; Nonato, FR; de Lima, FO; Couto, RD; David, JP; David, JM; Soares, MB; Villarreal, CF,期刊:Journal of natural products, 页码:2062-2068 , 文章类型: Article,,卷期:2011年74-10]
- Bergenin (1) is a C-glucoside of 4-O-methylgallic acid with known antiarthritic activity attributed to modulation of cytokine production. The present study was undertaken to evaluate whether 1 has antinociceptive propert...
- Biologically Active Arborinane-Type Triterpenoids and Anthraquinones from Rubia yunnanensis
[作者:Fan, JT; Kuang, B; Zeng, GZ; Zhao, SM; Ji, CJ; Zhang, YM; Tan, NH,期刊:Journal of natural products, 页码:2069-2080 , 文章类型: Article,,卷期:2011年74-10]
- Twelve new arborinane-type triterpenoids (1-12) and four new anthraquinones (13-16), together with 50 known compounds, were isolated from the roots of Rubia yunnanensis. The structures of 1-16 were elucidated by spectros...
- Benzofurans from Styrax agrestis As Acetylcholinesterase Inhibitors: Structure-Activity Relationships and Molecular Modeling Studies
[作者:Liu, JW; Dumontet, V; Simonin, AL; Iorga, BI; Guerineau, V; Litaudon, M; Van, HN; Gueritte, F,期刊:Journal of natural products, 页码:2081-2088 , 文章类型: Article,,卷期:2011年74-10]
- An extract of Styrax agrestis fruits, collected in Vietnam, significantly inhibited acetylcholinesterase (AChE) in vitro. Bioassay-guided fractionation revealed three new egonol-type benzofurans: egonol-9(Z),12(Z) linole...
- Diterpenes from the Hainan Soft Coral Lobophytum cristatum Tixier-Durivault
[作者:Li, L; Sheng, L; Wang, CY; Zhou, YB; Huang, H; Li, XB; Li, J; Mollo, E; Gavagnin, M; Guo, YW,期刊:Journal of natural products, 页码:2089-2094 , 文章类型: Article,,卷期:2011年74-10]
- Two new prenylgermacrane-type diterpenoids, lobophytumins A and B (1 and 2), two new prenyleudesmane-type diterpenoids, lobophytumins C and D (3 and 4), and two new spatane-type diterpenoids, lobophytumins E and F (5 and...
- Microbial Transformations of Diosgenin by the White-Rot Basidiomycete Coriolus versicolor
[作者:Wu, GW; Gao, JM; Shi, XW; Zhang, Q; Wei, SP; Ding, K,期刊:Journal of natural products, 页码:2095-2101 , 文章类型: Article,,卷期:2011年74-10]
- Microbial transformation of diosgenin (3 beta-hydroxy-5-spirostene) using white-rot fungus Coriolus versicolor afforded four previously unreported polyhydroxylated steroids, 25(R)-spirost-5-en-3 beta,7 alpha,15 alpha,21-...
- Growth Inhibition of Human Lung Cancer Cells via Down-regulation of Epidermal Growth Factor Receptor Signaling by Yuanhuadine, a Daphnane Diterpene from Daphne genkwa
[作者:Hong, JY; Chung, HJ; Lee, HJ; Park, HJ; Lee, SK,期刊:Journal of natural products, 页码:2102-2108 , 文章类型: Article,,卷期:2011年74-10]
- The growth inhibition and antitumor activities of yuanhuadine (1), a daphnane diterpenoid from the flowers of Daphne genkwa, were investigated in human lung cancer cells. a Compound 1 exhibited a relatively selective gro...
- Diarylheptanoids from the Seeds of Alpinia katsumadai as Heat Shock Factor 1 Inducers
[作者:Nam, JW; Kang, GY; Han, AR; Lee, D; Lee, YS; Seo, EK,期刊:Journal of natural products, 页码:2109-2115 , 文章类型: Article,,卷期:2011年74-10]
- Seven new diarylheptanoids, (-)-(R)-4 ''-hydroxyyashabushiketol (1), (3S,5S)-alpinikatin (2), katsumain C (3), 7-epi-katsumain C (4), ent-alpinnanin B (5), ent-alpinnanin A (6), and ent-calyxin H (8), were isolated from ...
- Triterpenoid Constituents from the Roots of Paeonia rockii ssp rockii
[作者:Mencherini, T; Picerno, P; Festa, M; Russo, P; Capasso, A; Aquino, R,期刊:Journal of natural products, 页码:2116-2121 , 文章类型: Article,,卷期:2011年74-10]
- An investigation of a chloroform-soluble extract from the roots of Paeonia rockii ssp. rockii yielded three new noroleanane triterpenoids (1-3) together with 19 known compounds. Their structures were established by analy...
- Antimalarial beta-Carboline and Indolactam Alkaloids from Marinactinospora thermotolerans, a Deep Sea Isolate
[作者:Huang, HB; Yao, YL; He, ZX; Yang, TT; Ma, JY; Tian, XP; Li, YY; Huang, CG; Chen, XP; Li, WJ; Zhang, S; Zhang, CS; Ju, JH,期刊:Journal of natural products, 页码:2122-2127 , 文章类型: Article,,卷期:2011年74-10]
- Four new beta-carboline alkaloids, designated marinacarbolines A D (1-4), two new indolactam alkaloids, 13-N-demethyl-methylpendolmycin (5) and methylpendolmy-cin-14-O-alpha-glucoside (6), and the three known compounds 1...
- Cytotoxic Triterpenoid Saponins from Lysimachia clethroides
[作者:Liang, D; Hao, ZY; Zhang, GJ; Zhang, QJ; Chen, RY; Yu, DQ,期刊:Journal of natural products, 页码:2128-2136 , 文章类型: Article,,卷期:2011年74-10]
- Seven oleanane-type triterpenoid saponins, named clethroidosides A-G (1-7), an ursane-type triterpenoid saponin, clethroidoside H (8), and six known saponins were isolated from the aerial parts of Lysimachia clethroides....
- Cyclodepsipeptides, Sesquiterpenoids, and Other Cytotoxic Metabolites from the Filamentous Fungus Trichothecium sp (MSX 51320)
[作者:Sy-Cordero, AA; Graf, TN; Adcock, AF; Kroll, DJ; Shen, Q; Swanson, SM; Wani, MC; Pearce, CJ; Oberlies, NH,期刊:Journal of natural products, 页码:2137-2142 , 文章类型: Article,,卷期:2011年74-10]
- Two new cyclodepsipeptides (1 and 2), two new sesquiterpenoids (3 and 4), and the known compounds guangomide A (5), roseotoxin S, and three simple trichothecenes were isolated from the cytotoxic organic extract of a terr...
- Lanostane and Hopane Triterpenes from the Entomopathogenic Fungus Hypocrella sp BCC 14524
[作者:Isaka, M; Chinthanom, P; Sappan, M; Chanthaket, R; Luangsa-Ard, JJ; Prabpai, S; Kongsaeree, P,期刊:Journal of natural products, 页码:2143-2150 , 文章类型: Article,,卷期:2011年74-10]
- Seven new lanostane-type triterpenes, hypocrellols A-G (1-7), and six new hopane-type triterpenes, 7 beta,15 alpha-dihydroxy-22(29)-hopene (8), 3 beta,7 beta-dihydroxy-22(29)-hopene (9), 3 beta-acetoxy-15 alpha-hydroxy-2...
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