- HSQC-1,1-ADEQUATE and HSQC-1,n-ADEQUATE: Enhanced Methods for Establishing Adjacent and Long-Range (13)C-(13)C Connectivity Networks
[作者:Martin, GE; Hilton, BD; Blinov, KA,期刊:Journal of natural products, 页码:2400-2407 , 文章类型: Article,,卷期:2011年74-11]
- (1)H-(13)C GHSQC and GHMBC spectra are irrefutably among the most valuable 2D NMR experiments for the establishment of unknown chemical structures. However, the indeterminate nature of the length of the long-range coupli...
- Inhibition of TNF-alpha-Induced Inflammation by Andrographolide via Down-Regulation of the PI3K/Akt Signaling Pathway
[作者:Chen, HW; Lin, AH; Chu, HC; Li, CC; Tsai, CW; Chao, CY; Wang, CJ; Lii, CK; Liu, KL,期刊:Journal of natural products, 页码:2408-2413 , 文章类型: Article,,卷期:2011年74-11]
- Andrographolide (1), an active constituent of Andrographis paniculata, decreased tumor necrosis factor-alpha (TNF-alpha)-induced intercellular adhesion molecule-1 (ICAM-1) expression and adhesion of HL-60 cells onto huma...
- Calysolins I-IV, Resin Glycosides from Calystegia soldanella
[作者:Takigawa, A; Muto, H; Kabata, K; Okawa, M; Kinjo, J; Yoshimitsu, H; Nohara, T; Ono, M,期刊:Journal of natural products, 页码:2414-2419 , 文章类型: Article,,卷期:2011年74-11]
- Four new resin glycosides having intramolecular cyclic ester structures (jalapins), named calysolins I-IV (1-4), were isolated from the methanol extract of leaves, stems, and roots of Calystegia soldanella, along with on...
- Jadomycins Derived from the Assimilation and Incorporation of Norvaline and Norleucine
[作者:Dupuis, SN; Veinot, T; Monro, SMA; Douglas, SE; Syvitski, RT; Goralski, KB; McFarland, SA; Jakeman, DL,期刊:Journal of natural products, 页码:2420-2424 , 文章类型: Article,,卷期:2011年74-11]
- Streptomyces venezuelae ISP5230 is recognized for the production of chloramphenicol and the jadomycin family of natural products. The jadomycins are angucycline natural products containing a unique oxazolone ring incorpo...
- Alkaloids from the Chinese Vine Gnetum montanum
[作者:Martin, F; Grkovic, T; Sykes, ML; Shelper, T; Avery, VM; Camp, D; Quinn, RJ; Davis, RA,期刊:Journal of natural products, 页码:2425-2430 , 文章类型: Article,,卷期:2011年74-11]
- During a high-throughput screening campaign of a prefractionated natural product library, fractions from the Chinese vine Gnetum montanum showed in vitro activity against Pseudomonas aeruginosa wild-type strain, PAO1. UV...
- Cucurbitane Glucosides from the Root of Machilus yaoshansis
[作者:Gan, ML; Liu, MT; Liu, B; Lin, S; Zhang, YL; Zi, JC; Song, WX; Ye, F; Chen, XG; Shi, JG,期刊:Journal of natural products, 页码:2431-2437 , 文章类型: Article,,卷期:2011年74-11]
- Seven new cucurbitane triteipene glucosides (1-5, 8, and 9) and five known analogues (6, 7, 10, cucurbitacin I 2-O-beta-D.glucopyranoside, and khekadaengoside K) have been isolated from an ethanol extract of roots of Mac...
- Indole Alkaloids and Quassinoids from the Stems of Brucea mollis
[作者:Chen, H; Bai, J; Fang, ZF; Yu, SS; Ma, SG; Xu, S; Li, Y; Qu, J; Ren, JH; Li, L; Si, YK; Chen, XG,期刊:Journal of natural products, 页码:2438-2445 , 文章类型: Article,,卷期:2011年74-11]
- Seven new indole alkaloids, bruceollines H-N (1-7), three new quassinoids, yadanziolides T-V (10-12), and four known analogues, bruceolline E (8), bruceolline F (9), bruceine D (13), and yadanziolide B (14), were isolate...
- Alkylated Flavanones from the Bark of Cryptocarya chartacea As Dengue Virus NS5 Polymerase Inhibitors
[作者:Allard, PM; Dau, ETH; Eydoux, C; Guillemot, JC; Dumontet, V; Poullain, C; Canard, B; Gueritte, F; Litaudon, M,期刊:Journal of natural products, 页码:2446-2453 , 文章类型: Article,,卷期:2011年74-11]
- An in vitro screening of New Caledonian plants allowed the selection of several species with a significant dengue virus NS5 RNA-dependent RNA polymerase (RdRp) inhibiting activity. The chemical investigation of Cryptocar...
- From Retrospective Assessment to Prospective Decisions in Natural Product Isolation: HPLC-SPE-NMR Analysis of Carthamus oxyacantha
[作者:Johansen, KT; Wubshet, SG; Nyberg, NT; Jaroszewski, JW,期刊:Journal of natural products, 页码:2454-2461 , 文章类型: Article,,卷期:2011年74-11]
- An extract of Carthamus oxyacantha (wild safflower) was investigated using two approaches: a traditional, nontarget fractionation by VLC and HPLC, and the hyphenated technique HPLC-PDA-HRMS-SPE-NMR followed by targeted i...
- Unprecedented Ultra-High-Resolution Hydroxy Group (1)H NMR Spectroscopic Analysis of Plant Extracts
[作者:Charisiadis, P; Primikyri, A; Exarchou, V; Tzakos, A; Gerothanassis, IP,期刊:Journal of natural products, 页码:2462-2466 , 文章类型: Article,,卷期:2011年74-11]
- A general method is demonstrated for obtaining ultra-high resolution in the phenolic hydroxy group (1)H NMR spectroscopic region, in DMSO-d(6) solution, with the addition of picric acid. Line-width reduction by a factor ...
- Klymollins A-H, Bioactive Eunicellin-Based Diterpenoids from the Formosan Soft Coral Klyxum molle
[作者:Hsu, FJ; Chen, BW; Wen, ZH; Huang, CY; Dai, CF; Su, JH; Wu, YC; Sheu, JH,期刊:Journal of natural products, 页码:2467-2471 , 文章类型: Article,,卷期:2011年74-11]
- Eight new eunicellin-based diterpenoids, klymollins A-H (1-8), were isolated during the chemical investigation of the soft coral Klyxum molle from Taiwan waters:. Their structures were elucidated by extensive spectroscop...
- Phenolic Glycosides from Sugar Maple (Acer saccharum) Bark
[作者:Yuan, T; Wan, CP; Gonzalez-Sarrias, A; Kandhi, V; Cech, NB; Seeram, NP,期刊:Journal of natural products, 页码:2472-2476 , 文章类型: Article,,卷期:2011年74-11]
- Four new phenolic glycosides, saccharumosides A-D (1-4), along with eight known phenolic glycosides, were isolated from the bark of sugar maple (Acer saccharum). The structures of 1-4 were elucidated on the basis of spec...
- Cytotoxic Bistetrahydrofuran Annonaceous Acetogenins from the Seeds of Annona squamosa
[作者:Chen, Y; Chen, JW; Li, X,期刊:Journal of natural products, 页码:2477-2481 , 文章类型: Article,,卷期:2011年74-11]
- Three new bistetrahydrofuran annonaceous acetogenins (1-3) were isolated from a 95% EtOH extract of Annona squamosa seeds. Four known annonaceous acetogenins, uvarigrandin A (4), bullatacin (5), squamostatin-A (6), and s...
- Benzylisoquinoline Alkaloids from the Papaveraceae: The Heritage of Johannes Gadamer (1867-1928)
[作者:Meyer, A; Imming, P,期刊:Journal of natural products, 页码:2482-2487 , 文章类型: Review,,卷期:2011年74-11]
- The substance archive of the laboratory of Johannes Gadamer (1867-1928), Marburg, Germany, was analyzed thoroughly with modem instrumental methods, with the samples purified when necessary, and the authenticity of the sa...
- Bacterial Production of the Tunicate-Derived Antitumor Cyclic Depsipeptide Didemnin B
[作者:Tsukimoto, M; Nagaoka, M; Shishido, Y; Fujimoto, J; Nishisaka, F; Matsumoto, S; Harunari, E; Imada, C; Matsuzaki, T,期刊:Journal of natural products, 页码:2329-2331 , 文章类型: Article,,卷期:2011年74-11]
- Natural products obtained from marine invertebrates such as sponges and tunicates are attractive sources of drugs. However, a critical obstacle in the development of these compounds is the problem of supply. In most case...
- Semisynthesis and Biological Evaluation of Ganodermanontriol and Its Stereoisomeric Triols
[作者:Kennedy, EM; P'Pool, SJ; Jiang, JH; Sliva, D; Minto, RE,期刊:Journal of natural products, 页码:2332-2337 , 文章类型: Article,,卷期:2011年74-11]
- The first synthesis of ganodermanontriol, a bioactive lanostane triterpene from the medicinal mushroom Ganoderma lucidum, has been achieved in 15.3% yield over nine steps, along with its three stereoisomeric triols and g...
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