- Secondary Metabolites from the Roots of Neolitsea daibuensis and Their Anti-inflammatory Activity
[作者:Wong, SL; Chang, HS; Wang, GJ; Chiang, MY; Huang, HY; Chen, CH; Tsai, SC; Lin, CH; Chen, IS,期刊:Journal of natural products, 页码:2489-2496 , 文章类型: Article,,卷期:2011年74-12]
- Bioassay-guided fractionation of the roots of Neolitsea daibuensis afforded three new beta-carboline alkaloids, daibucarbolines A-C (1-3), three new sesquiterpenoids, daibulactones A and B (4 and 5) and daibuoxide (6), a...
- Xanthohumol Induces Apoptosis in Human Malignant Glioblastoma Cells by Increasing Reactive Oxygen Species and Activating MAPK Pathways
[作者:Festa, M; Capasso, A; D'Acunto, CW; Masullo, M; Rossi, AG; Pizza, C; Piacente, S,期刊:Journal of natural products, 页码:2505-2513 , 文章类型: Article,,卷期:2011年74-12]
- The effect of the biologically active prenylated chalcone and potential anticancer agent xanthohumol (1) has been investigated on apoptosis of the T98G human malignant glioblastoma cell line. Compound 1 decreased the via...
- Isoflavonoids and Coumarins from Glycyrrhiza uralensis: Antibacterial Activity against Oral Pathogens and Conversion of Isoflavans into Isoflavan-Quinones during Purification
[作者:Gafner, S; Bergeron, C; Villinski, JR; Godejohann, M; Kessler, P; Cardellina, JH; Ferreira, D; Feghali, K; Grenier, D,期刊:Journal of natural products, 页码:2514-2519 , 文章类型: Article,,卷期:2011年74-12]
- Phytochemical investigation of a supercritical fluid extract of Glycyrrhiza uralensis has led to the isolation of 20 known isoflavonoids and coumarins, and glycycarpan (7), a new pterocarpan. The presence of two isoflava...
- In Vitro Antibacterial Activity of Sphaeropsidins and Chemical Derivatives toward Xanthomonas oryzae pv. oryzae, the Causal Agent of Rice Bacterial Blight
[作者:Evidente, A; Venturi, V; Masi, M; Degrassi, G; Cimmino, A; Maddau, L; Andolfi, A,期刊:Journal of natural products, 页码:2520-2525 , 文章类型: Article,,卷期:2011年74-12]
- Sphaeropsidin A, the main phytotoxin produced by Diplodia cupressi, as well as the two natural analogues sphaeropsidins B and C and 14 derivatives obtained by chemical modifications were assayed for antibacterial activit...
- ent-Kaurane Diterpenoids from Croton tonkinensis Stimulate Osteoblast Differentiation
[作者:Dao, TT; Lee, KY; Jeong, HM; Nguyen, PH; Tran, TL; Thuong, PT; Nguyen, BT; Oh, WK,期刊:Journal of natural products, 页码:2526-2531 , 文章类型: Article,,卷期:2011年74-12]
- Four new ent-kaurane diterpenoids (1-4) were isolated from the leaves of Croton tonkinensis by bioactivity-guided fractionation using an in vitro osteoblast differentiation assay. Their structures were identified as ent-...
- Cytotoxic Withanolide Constituents of Physalis longifolia
[作者:Zhang, HP; Samadi, AK; Gallagher, RJ; Araya, JJ; Tong, XQ; Day, VW; Cohen, MS; Kindscher, K; Gollapudi, R; Timmermann, BN,期刊:Journal of natural products, 页码:2532-2544 , 文章类型: Article,,卷期:2011年74-12]
- Fourteen new withanolides, 1-14, named withalongolides A-N, respectively, were isolated from the aerial parts of Physalis longifolia together with eight known compounds (15-22). The structures of compounds 1-14 were eluc...
- Natural Product Libraries to Accelerate the High-Throughput Discovery of Therapeutic Leads
[作者:Johnson, TA; Sohn, J; Inman, WD; Estee, SA; Loveridge, ST; Vervoort, HC; Tenney, K; Liu, JK; Ang, KKH; Ratnam, J; Bray, WM; Gassner, NC; Shen, YY; Lokey, RS; McKerrow, JH; Boundy-Mills, K; Nukanto, A; Kanti, A; Julistiono, H; Kardono, LBS; Bjeldanes, LF; Crews, P,期刊:Journal of natural products, 页码:2545-2555 , 文章类型: Article,,卷期:2011年74-12]
- A high-throughput (HT) paradigm generating LC-MS-UV-ELSD-based natural product libraries to discover compounds with new bioactivities and or molecular structures is presented. To validate this methodology, an extract of ...
- Lumutinines A-D, Linearly Fused Macroline-Macroline and Macroline-Sarpagine Bisindoles from Alstonia macrophylla
[作者:Lim, SH; Tan, SJ; Low, YY; Kam, TS,期刊:Journal of natural products, 页码:2556-2562 , 文章类型: Article,,卷期:2011年74-12]
- Four new linearly fused bisindole alkaloids, lumutinines A D (1-4), were isolated from the stem-bark extract of Alstonia macrophylla. Lumutinines A (1) and B (2) represent the first examples of linear, ring A/F-fused mac...
- Triterpene Galactosides of the Pouoside Class and Corresponding Aglycones from the Sponge Lipastrotethya sp.
[作者:Lee, JH; Jang, KH; Lee, YJ; Lee, HS; Sim, CJ; Oh, KB; Shin, J,期刊:Journal of natural products, 页码:2563-2570 , 文章类型: Article,,卷期:2011年74-12]
- Nine new triterpene galactosides and aglycones, along with three known compounds from the rare pouoside class, were isolated from the tropical sponge Lipastrotethya sp. collected from Micronesia. The structures of these ...
- Cyclopeptide Alkaloids from Ziziphus apetala
[作者:Han, J; Ji, CJ; He, WJ; Shen, Y; Leng, Y; Xu, WY; Fan, JT; Zeng, GZ; Kong, LD; Tan, NH,期刊:Journal of natural products, 页码:2571-2575 , 文章类型: Article,,卷期:2011年74-12]
- Six novel Ia(3)-type cyclopeptide alkaloids (1-6) were isolated from stems of Ziziphus apetala. Compound 5 and the known compounds mauritine A (7) and mauritine F (8) were isolated from the roots. Their structures were d...
- Constituents of Trigonostemon heterophyllus
[作者:Dong, SH; Liu, HB; Xu, CH; Ding, J; Yue, JM,期刊:Journal of natural products, 页码:2576-2581 , 文章类型: Article,,卷期:2011年74-12]
- Six new diterpenoids, 1-6, a new prenylated sesquiterpenoid, 7, and six known compounds were isolated from Trigonostemon heterophyllus. The structures of 1-7 were elucidated on the basis of NMR and MS analysis. The daphn...
- Cyclic Ether-Containing Macrolactins, Antimicrobial 24-Membered Isomeric Macrolactones from a Marine Bacillus sp.
[作者:Mondol, MAM; Tareq, FS; Kim, JH; Lee, MA; Lee, HS; Lee, YJ; Lee, JS; Shin, HJ,期刊:Journal of natural products, 页码:2582-2587 , 文章类型: Article,,卷期:2011年74-12]
- Bioassay-guided isolation of bioactive metabolites from the ethyl acetate extract of a marine Bacillus sp. fermentation broth has led to the discovery of three new 24-membered macrolactones, macrolactins 1-3, which conta...
- Naphthoquinone-like Polyketide Isolated from Streptomyces sp RI-77 and Its Predicted Biosynthetic Pathway
[作者:Izumikawa, M; Satou, R; Motohashi, K; Nagai, A; Ohnishi, Y; Takagi, M; Shin-ya, K,期刊:Journal of natural products, 页码:2588-2591 , 文章类型: Article,,卷期:2011年74-12]
- A novel naphthoquinone-like polyketide, JBIR-85 (1), with a unique skeleton and antioxidative activity was isolated from a culture of Streptomyces sp. RI-77. The planar structure of 1 was established on the basis of exte...
- Acremostrictin, a Highly Oxygenated Metabolite from the Marine Fungus Acremonium strictum
[作者:Julianti, E; Oh, H; Jang, KH; Lee, JK; Lee, SK; Oh, DC; Oh, KB; Shin, J,期刊:Journal of natural products, 页码:2592-2594 , 文章类型: Article,,卷期:2011年74-12]
- The novel natural product acremostrictin (1) was isolated from the culture broth of Acremonium strictum, a marine fungus collected from a Choristida sponge off the coast of Korea. Structurally, acremostrictin is a tricyc...
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