- Mirabamides E-H, HIV-Inhibitory Depsipeptides from the Sponge Stelletta clavosa
[作者:Lu, ZY; Van Wagoner, RM; Harper, MK; Baker, HL; Hooper, JNA; Bewley, CA; Ireland, CM,期刊:Journal of natural products, 页码:185-193 , 文章类型: Article,,卷期:2011年74-2]
- Four new depsipeptides, mirabamides E-H (1-4), and the known depsipeptide mirabamide C (5) have been isolated from the sponge Stelletta clavosa, collected from the Torres Strait. The planar structures were determined on ...
- Configurational Assignment of Cyclic Peroxy Metabolites Provides an Insight into Their Biosynthesis: Isolation of Plakortolides, seco-Plakortolides, and Plakortones from the Australian Marine Sponge Plakinastrella clathrata
[作者:Yong, KWL; De Voss, JJ; Hooper, JNA; Garson, MJ,期刊:Journal of natural products, 页码:194-207 , 文章类型: Article,,卷期:2011年74-2]
- Sixteen new compounds, comprising nine new plakortolides K-S (1-9), four seco-plakortolides (10-13), and three plakortones (14-16), were isolated from the Australian sponge Plakinastrella clathrata. Structural elucidatio...
- Claurailas A-D, Cytotoxic Carbazole Alkaloids from the Roots of Clausena harmandiana
[作者:Songsiang, U; Thongthoom, T; Boonyarat, C; Yenjai, C,期刊:Journal of natural products, 页码:208-212 , 文章类型: Article,,卷期:2011年74-2]
- Four new carbazole alkaloids, claurailas A-D (1-4), as well as 12 known carbazoles and three known coumarins were isolated from the roots of Clausena harmandiana. Heptaphylline (6) and 7-methoxyheptaphylline (7) showed s...
- Dolabellanes with Antibacterial Activity from the Brown Alga Dilophus spiralis
[作者:Ioannou, E; Quesada, A; Rahman, MM; Gibbons, S; Vagias, C; Roussis, V,期刊:Journal of natural products, 页码:213-222 , 文章类型: Article,,卷期:2011年74-2]
- Seventeen diterpenes featuring the dolabellane skeleton (1-17) were isolated from the organic extracts of the brown alga Dilophus spiralis. Seven compounds are new natural products (1, 3, 5, 6, 11, 14, 15) and eight are ...
- Lauroside B, a Megastigmane Glycoside from Laurus Nobilis (Bay Laurel) Leaves, Induces Apoptosis in Human Melanoma Cell Lines by Inhibiting NF-kappa B Activation
[作者:Panza, E; Tersigni, M; Iorizzi, M; Zollo, F; De Marino, S; Festa, C; Napolitano, M; Castello, G; Ialenti, A; Ianaro, A,期刊:Journal of natural products, 页码:228-233 , 文章类型: Article,,卷期:2011年74-2]
- Malignant melanoma is a highly aggressive tumor that frequently resists chemotherapy, so the search for new agents for its treatment is of great importance. In the present study, the antiproliferative propensity against ...
- Terpenoids and Norlignans from Metasequoia glyptostroboides
[作者:Dong, LB; He, J; Wang, YY; Wu, XD; Deng, X; Pan, ZH; Xu, G; Peng, LY; Zhao, Y; Li, Y; Gong, X; Zhao, QS,期刊:Journal of natural products, 页码:234-239 , 文章类型: Article,,卷期:2011年74-2]
- Four new terpenoids, metaseglyptorin A (1), metasequoic acid C (2), 12 alpha-hydroxy-8,15-isopimaradien-18-oic acid (3), and (-)-acora-2,4(14),8-trien-15-oic acid (4), and three new norlignans, metasequirins D-F (5-7), w...
- Natural and Semisynthetic Mammea-Type Isoprenylated Dihydroxycoumarins Uncouple Cellular Respiration
[作者:Du, L; Mandi, F; Jekabsons, MB; Nagle, DG; Zhou, YD,期刊:Journal of natural products, 页码:240-248 , 文章类型: Article,,卷期:2011年74-2]
- In an effort to identify natural product-based molecular-targeted antitumor agents, mammea-type coumarins from the tropical/subtropical plant Mammea americana were found to inhibit the activation of HIF-1 (hypoxia-induci...
- Cycloartane Triterpenes Isolated from Combretum quadrangulare in a Screening Program for Death-Receptor Expression Enhancing Activity
[作者:Toume, K; Nakazawa, T; Ohtsuki, T; Arai, MA; Koyano, T; Kowithayakorn, T; Ishibashi, M,期刊:Journal of natural products, 页码:249-255 , 文章类型: Article,,卷期:2011年74-2]
- In our screening program for natural products that increase DR5 (death-receptor 5) expression, nine new cycloartane triterpenes, combretanones A-G (1-7), combretic acid A (8), and combretic acid B (9), were isolated from...
- Comazaphilones A-F, Azaphilone Derivatives from the Marine Sediment-Derived Fungus Penicillium commune QSD-17
[作者:Gao, SS; Li, XM; Zhang, Y; Li, CS; Cui, CM; Wang, BG,期刊:Journal of natural products, 页码:256-261 , 文章类型: Article,,卷期:2011年74-2]
- Chemical investigation of Penicillium commune QSD-17, a fungus isolated from a marine sediment sample collected in the southern Chinai Sea, yielded six new azaphilone derivatives, namely, comazaphilones A-F (1-6). The st...
- Flavonoids from Eight Tropical Plant Species That Inhibit the Multidrug Resistance Transporter ABCG2
[作者:Versiani, MA; Diyabalanage, T; Ratnayake, R; Henrich, CJ; Bates, SE; McMahon, JB; Gustafson, KR,期刊:Journal of natural products, 页码:262-266 , 文章类型: Article,,卷期:2011年74-2]
- Overexpression of ABCG2, a membrane-bound multidrug transporter, can make tumor cells resistant to treatment with conventional chemotherapeutic agents. A high-throughput screening effort with the NCI repository of natura...
- Dinoxin B, a Withanolide from Datura inoxia Leaves with Specific Cytotoxic Activities
[作者:Vermillion, K; Holguin, FO; Berhow, MA; Richins, RD; Redhouse, T; O'Connell, MA; Posakony, J; Mahajan, SS; Kelly, SM; Simon, JA,期刊:Journal of natural products, 页码:267-271 , 文章类型: Article,,卷期:2011年74-2]
- A new withanolide, dinoxin B (12,21-dihydroxy-1-oxowitha-2,5,24-trienolide-27-O-beta-D-glucopyranoside, 1), was isolated from a methanol extract of Datum inoxia leaves, using bioassay-guided fractionation. The structure ...
- Antimicrobial Isopropenyl-dihydrofuranoisoflavones from Crotalaria lachnophora
[作者:Awouafack, MD; Spiteller, P; Lamshoft, M; Kusari, S; Ivanova, B; Tane, P; Spiteller, M,期刊:Journal of natural products, 页码:272-278 , 文章类型: Article,,卷期:2011年74-2]
- Two new isopropenyl-dihydrofuranoisoflavones exhibiting antimicrobial properties have been isolated along with eight known compounds from the Cameroonian medicinal plant Crotalaria lachnophora. The Structures of the new ...
- Oroidin Inhibits the Activity of the Multidrug Resistance Target Pdr5p from Yeast Plasma Membranes
[作者:da Silva, FR; Tessis, AC; Ferreira, PF; Rangel, LP; Garcia-Gomes, AS; Pereira, FR; Berlinck, RGS; Muricy, G; Ferreira-Pereira, A,期刊:Journal of natural products, 页码:279-282 , 文章类型: Article,,卷期:2011年74-2]
- Oroidin was isolated from the marine sponge Agelas sventres and inhibited the activity and function of Pdr5p, an enzyme responsible for the multidrug resistance phenotype in Saccharomyces cerevisiae. This compound may he...
- Sapotexanthin, an A-Provitamin Carotenoid from Red Mamey (Pouteria sapota)
[作者:Murillo, E; McLean, R; Britton, G; Attila, A; Veronika, N; Jozsef, D,期刊:Journal of natural products, 页码:283-285 , 文章类型: Article,,卷期:2011年74-2]
- From the ripe fruits of red mamey (Pouteria sapota) sapotexanthin, a new carotenoid, was identified as (all-E,5'R)-beta,k-caroten-6'-one.
- Pestaloquinols A and B, Isoprenylated Epoxyquinols from Pestalotiopsis sp.
[作者:Ding, G; Zhang, F; Chen, H; Guo, LD; Zou, ZM; Che, YS,期刊:Journal of natural products, 页码:286-291 , 文章类型: Article,,卷期:2011年74-2]
- Two new isoprenylated epoxyquinol derivatives, pestaloquinols A (2) and B (3), and their putative biosynthetic precursor, cytosporin D (1), were isolated from the crude extract of the plant endophytic fungus Pestalotiops...
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