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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共43条记录   Role of the Apoptotic and Mitotic Regulator Survivin in Melanoma [作者：Mckenzie, JA; Grossman, D,期刊：Anticancer Research, 页码：397-404 , 文章类型： Review，,卷期：2012年32-2] Melanoma is the deadliest form of skin cancer. Melanoma develops in response to genetic and environmental pressures which lead to oncogenic transformation of normal human melanocytes, the pigment-producing cells in the b... Tumor Interstitial Fluid as Modulator of Cancer Inflammation, Thrombosis, Immunity and Angiogenesis [作者：Baronzio, G; Schwartz, L; Kiselevsky, M; Guais, A; Sanders, E; Milanesi, G; Baronzio, M; Freitas, I,期刊：Anticancer Research, 页码：405-414 , 文章类型： Review，,卷期：2012年32-2] Tumor interstitial fluid (TIF) is a watery phase that accumulates inside the tumor interstitium. Its genesis and fate depend on various factors, namely tumor type, metabolic state of the tumor, expression of vascular end... Quantitative MRI Establishes the Efficacy of PI3K Inhibitor (GDC-0941) Multi-Treatments in PTEN-deficient Mice Lymphoma [作者：Wullschleger, S; Garcia-Martinez, JM; Duce, SL,期刊：Anticancer Research, 页码：415-420 , 文章类型： Article，,卷期：2012年32-2] Aim: To assess the efficacy of multiple treatment of phosphatidylinositol-3-kinase (PI3K) inhibitor on autochthonous tumours in phosphatase and tensin homologue (Pten)-deficient genetically engineered mouse cancer models... Polymorphisms of the Epidermal Growth Factor Receptor (EGFR) and Survival in Patients with Advanced Cancer of the Head and Neck (HNSCC) [作者：Stoehlmacher-Williams, J; Obermann, L; Ehninger, G; Goekkurt, E,期刊：Anticancer Research, 页码：421-425 , 文章类型： Article，,卷期：2012年32-2] Aim: Associations between polymorphisms of the epidermal growth factor receptor (EGFR) and overall survival in patients with advanced carcinoma of the head and neck (HNSCC) receiving cetuximab based palliative treatment,... Oncogenic MST1R Activity in Pancreatic and Gastric Cancer Represents a Valid Target of HSP90 Inhibitors [作者：Moser, C; Lang, SA; Hackl, C; Zhang, H; Lundgren, K; Hong, V; Mckenzie, A; Weber, B; Park, JS; Schlitt, HJ; Geissler, EK; Jung, YD; Stoeltzing, O,期刊：Anticancer Research, 页码：427-437 , 文章类型： Article，,卷期：2012年32-2] Aim: To evaluate the effects of HSP90 blockade by EC154 on the oncogenic receptor tyrosine kinase macrophage-stimulating 1 receptor (MST1R) in gastric and pancreatic cancer. Materials and Methods: Impact of EC154 on sign... Elevated Expression of IRS2 in the Progression from Neurofibroma to Malignant Peripheral Nerve Sheath Tumor [作者：Shaw, CM; Grobmyer, SR; Ucar, DA; Cance, WG; Reith, JD; Hochwald, SN,期刊：Anticancer Research, 页码：439-443 , 文章类型： Article，,卷期：2012年32-2] Background/Aim: Novel drugs to inhibit insulin receptor substrate (IRS) and focal adhesion kinase (FAK) pathways are emerging and will be sarcoma subtype-specific. As a result, defining expression of proteins in these pa... Effect of PI3K/Akt Pathway Inhibition-Mediated G(1) Arrest on Chemosensitization in Ovarian Cancer Cells [作者：Fekete, M; Santiskulvong, C; Eng, C; Dorigo, O,期刊：Anticancer Research, 页码：445-452 , 文章类型： Article，,卷期：2012年32-2] Background: Pharmacological inhibition of the phosphoinositide 3-kinase (PI3K)/Akt pathway prevents G(1) cell cycle progression into S, resulting in G(1) accumulation. The hypothesis that this arrest might negatively imp... Preclinical Activity of the Novel Orally Bioavailable HSP90 Inhibitor NVP-HSP990 against Multiple Myeloma Cells [作者：Stuhmer, T; Iskandarov, K; Gao, ZH; Bumm, T; Grella, E; Jensen, MR; Einsele, H; Chatterjee, M; Bargou, RC,期刊：Anticancer Research, 页码：453-462 , 文章类型： Article，,卷期：2012年32-2] Background: HSP90 inhibitors effectively reduce expression and activity levels of oncogenic survival proteins. However, their clinical anti-multiple myeloma (MM) activity has been found to be rather weak, spurring the ex... The Dual Kinase Inhibitor NVP-BEZ235 in Combination with Cytotoxic Drugs Exerts Anti-proliferative Activity towards Acute Lymphoblastic Leukemia Cells [作者：Schult, C; Dahlhaus, M; Glass, A; Fischer, K; Lange, S; Freund, M; Junghanss, C,期刊：Anticancer Research, 页码：463-474 , 文章类型： Article，,卷期：2012年32-2] Background: Inhibition of signal transduction pathways has been successfully introduced into cancer treatment. The dual phosphatidylinositol 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) inhibitor NVP-BEZ235 h... Evaluation of Breast Cancer Susceptibility Loci on 2q35, 3p24, 17q23 and FGFR2 Genes in Taiwanese Women with Breast Cancer [作者：Lin, CY; Ho, CM; Bau, DT; Yang, SF; Liu, SH; Lin, PH; Lin, TH; Tien, N; Shih, MC; Lu, JJ,期刊：Anticancer Research, 页码：475-482 , 文章类型： Article，,卷期：2012年32-2] Aim: Breast cancer is the most common cancer in women. In recent years, mounting evidence has identified the possibility that 2q35, 3p24, 17q23 and fibroblast growth factor receptor 2 (FGFR2) may be genetic susceptibilit... Caveolin-1 Attenuates Hydrogen Peroxide-induced Oxidative Damage to Lung Carcinoma Cells [作者：Suchaoin, W; Chanvorachote, P,期刊：Anticancer Research, 页码：483-490 , 文章类型： Article，,卷期：2012年32-2] Background: Oxidative stress has been shown to play an important role in cancer progression. In lung cancer, increasing expression of caveolin-1 (Cav-1) has been found in both primary and metastatic carcinomas and may be... C-reactive Protein is a Potential Prognostic Factor for Metastatic Gastric Cancer [作者：Shimura, T; Kitagawa, M; Yamada, T; Ebi, M; Mizoshita, T; Tanida, S; Kataoka, H; Kamiya, T; Joh, T,期刊：Anticancer Research, 页码：491-496 , 文章类型： Article，,卷期：2012年32-2] Background/Aim: C-reactive protein (CRP) has been associated with the development of many carcinomas, but the significance of CRP remains unclear for metastatic gastric cancer (MGC). Patients and Methods: Sixty one patie... Involvement of MAP Kinases in the Cytotoxicity of Acyclic Nucleoside Phosphonates [作者：Mertlikova-Kaiserova, H; Nejedla, M; Holy, A; Votruba, I,期刊：Anticancer Research, 页码：497-501 , 文章类型： Article，,卷期：2012年32-2] Background: 9[2-(phosphonomethoxy)ethyl] guanine (PMEG) is a nucleotide analogue with anticancer activity. Here we investigate the role of ERK, p38, INK and AKT kinases in PMEG-induced apoptosis. Materials and Methods: C... Expression Profiles of Signal Transduction Genes in Ex Vivo Drug-resistant Pediatric Acute Lymphoblastic Leukemia [作者：Szczepanek, J; Pogorzala, M; Jarzab, M; Oczko-Wojciechowska, M; Kowalska, M; Tretyn, A; Wysocki, M; Jarzab, B; Styczynski, J,期刊：Anticancer Research, 页码：503-506 , 文章类型： Article，,卷期：2012年32-2] Aim: Identification of signal transduction genes related to drug resistance in pediatric acute lymphoblastic leukemia (ALL). Materials and Methods: Ex vivo drug resistance in 107 children, divided into study and validati... Putative Supramolecular Complexes Formed by Carotenoids and Xanthophylls with Ascorbic Acid to Reverse Multidrug Resistance in Cancer Cells [作者：Molnar, J; Serly, J; Pusztai, R; Vincze, I; Molnar, P; Horvath, G; Deli, J; Maoka, T; Zalatnai, A; Tokuda, H; Nishino, H,期刊：Anticancer Research, 页码：507-517 , 文章类型： Article，,卷期：2012年32-2] Background: The molecular basis of interaction of selected carotenoids and xanthophylls with ascorbic acid on cancer cells was studied to determine their anticancer effects. Materials and Methods: Drug accumulation was m... Cytotoxicity of Hydrophylic Silver Carboxylato Complexes [作者：Fourie, E; Erasmus, E; Swarts, JC; Tuchscherer, A; Jakob, A; Lang, H; Joone, GK; Van Rensburg, CEJ,期刊：Anticancer Research, 页码：519-522 , 文章类型： Article，,卷期：2012年32-2] Background: Gold(I) and platinum(II) d(10) and d(8) electronic complexes such as (Au(PPh2CH2CH2PPh2)(2))Cl and cisplatin, ((H3N)(2)PtCl2), possess strong antineoplastic activities. Almost no information is available rega...