- Reversibility of Adverse, Calcineurin-Dependent Cardiac Remodeling
[作者：Berry, JM; Le, V; Rotter, D; Battiprolu, PK; Grinsfelder, B; Tannous, P; Burchfield, JS; Czubryt, M; Backs, J; Olson, EN; Rothermel, BA; Hill, JA,期刊：Circulation Research, 页码：407-U183 , 文章类型： Article，,卷期：2011年109-4]
- Rationale: Studies to dissect the role of calcineurin in pathological cardiac remodeling have relied heavily on murine models, in which genetic gain-and loss-of-function manipulations are initiated at or before birth. Ho...
- AIP1 Prevents Graft Arteriosclerosis by Inhibiting Interferon-gamma-Dependent Smooth Muscle Cell Proliferation and Intimal Expansion
[作者：Yu, LY; Qin, LF; Zhang, HF; He, Y; Chen, H; Pober, JS; Tellides, G; Min, W,期刊：Circulation Research, 页码：418-U210 , 文章类型： Article，,卷期：2011年109-4]
- Rationale: ASK1-interacting protein-1 (AIP1), a Ras GTPase-activating protein family member, is highly expressed in endothelial cells and vascular smooth musccells (VSMCs). The role of AIP1 in VSMCs and VSMC proliferativ...
- Intramyocardial, Autologous CD34+Cell Therapy for Refractory Angina
[作者：Losordo, DW; Henry, TD; Davidson, C; Lee, JS; Costa, MA; Bass, T; Mendelsohn, F; Fortuin, FD; Pepine, CJ; Traverse, JH; Amrani, D; Ewenstein, BM; Riedel, N; Story, K; Barker, K; Povsic, TJ; Harrington, RA; Schatz, RA,期刊：Circulation Research, 页码：428-U235 , 文章类型： Article，,卷期：2011年109-4]
- Rationale: A growing number of patients with coronary disease have refractory angina. Preclinical and early-phase clinical data suggest that intramyocardial injection of autologous CD34+ cells can improve myocardial perf...
- Small-Molecule Inhibitors of the Wnt Pathway Potently Promote Cardiomyocytes From Human Embryonic Stem Cell-Derived Mesoderm
[作者：Willems, E; Spiering, S; Davidovics, H; Lanier, M; Xia, ZB; Dawson, M; Cashman, J; Mercola, M,期刊：Circulation Research, 页码：360-U38 , 文章类型： Article，,卷期：2011年109-4]
- Rationale: Human embryonic stem cells can form cardiomyocytes when cultured under differentiation conditions. Although the initiating step of mesoderm formation is well characterized, the subsequent steps that promote fo...
- Enzymatic Single-Chain Antibody Tagging A Universal Approach to Targeted Molecular Imaging and Cell Homing in Cardiovascular Disease
[作者：Ta, HT; Prabhu, S; Leitner, E; Jia, F; von Elverfeldt, D; Jackson, KE; Heidt, T; Nair, AKN; Pearce, H; von zur Muhlen, C; Wang, X; Peter, K; Hagemeyer, CE,期刊：Circulation Research, 页码：365-U67 , 文章类型： Article，,卷期：2011年109-4]
- Rationale: Antibody-targeted delivery of imaging agents can enhance the sensitivity and accuracy of current imaging techniques. Similarly, homing of effector cells to disease sites increases the efficacy of regenerative ...
- Genetic Deletion of Chemokine Receptor Ccr6 Decreases Atherogenesis in ApoE-Deficient Mice
[作者：Wan, WZ; Lim, JK; Lionakis, MS; Rivollier, A; McDermott, DH; Kelsall, BL; Farber, JM; Murphy, PM,期刊：Circulation Research, 页码：374-U91 , 文章类型： Article，,卷期：2011年109-4]
- Rationale: The chemokine receptor Ccr6 is a G-protein-coupled receptor expressed on various types of leukocytes identified in mouse atherosclerotic lesions. Recent evidence suggests that both CCR6 and its ligand CCL20 ar...
- Ets2 Determines the Inflammatory State of Endothelial Cells in Advanced Atherosclerotic Lesions
[作者：Cheng, C; Tempel, D; Den Dekker, WK; Haasdijk, R; Chrifi, I; Bos, FL; Wagtmans, K; van de Kamp, EH; Blonden, L; Biessen, EAL; Moll, F; Pasterkamp, G; Serruys, PW; Schulte-Merker, S; Duckers, HJ,期刊：Circulation Research, 页码：385-U130 , 文章类型： Article，,卷期：2011年109-4]
- Rationale: Neovascularization is required for embryonic development and plays a central role in diseases in adults. In atherosclerosis, the role of neovascularization remains to be elucidated. In a genome-wide microarray...
- Caloric Restriction Primes Mitochondria for Ischemic Stress by Deacetylating Specific Mitochondrial Proteins of the Electron Transport Chain
[作者：Shinmura, K; Tamaki, K; Sano, M; Nakashima-Kamimura, N; Wolf, AM; Amo, T; Ohta, S; Katsumata, Y; Fukuda, K; Ishiwata, K; Suematsu, M; Adachi, T,期刊：Circulation Research, 页码：396-U153 , 文章类型： Article，,卷期：2011年109-4]
- Rationale: Caloric restriction (CR) confers cardioprotection against ischemia/reperfusion injury. However, the exact mechanism(s) underlying CR-induced cardioprotection remain(s) unknown. Recent evidence indicates that S...
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