- beta-arrestins regulate atherosclerosis and neointimal hyperplasia by controlling smooth muscle cell proliferation and migration
[作者：Kim, J; Zhang, L; Peppel, K; Wu, JH; Zidar, DA; Brian, L; DeWire, SM; Exum, ST; Lefkowitz, RJ; Freedman, NJ,期刊：Circulation Research, 页码：70-79 , 文章类型： Article，,卷期：2008年103-1]
- Atherosclerosis and arterial injury-induced neointimal hyperplasia involve medial smooth muscle cell (SMC) proliferation and migration into the arterial intima. Because many 7-transmembrane and growth factor receptors pr...
- Endothelial nitric oxide synthase gene expression during murine embryogenesis - Commencement of expression in the embryo occurs with the establishment of a unidirectional circulatory system
[作者：Teichert, AM; Scott, JA; Robb, GB; Zhou, YQ; Zhu, SN; Lem, M; Keightley, A; Steer, BM; Schuh, AC; Adamson, SL; Cybulsky, MI; Marsden, PA,期刊：Circulation Research, 页码：24-33 , 文章类型： Article，,卷期：2008年103-1]
- To elucidate the role of endothelial NO synthase (eNOS)-derived NO during mammalian embryogenesis, we assessed the expression of the eNOS gene during development. Using transgenic eNOS promoter/reporter mice (with beta-g...
- Estrogen receptor-alpha and endothelial nitric oxide synthase nuclear complex regulates transcription of human telomerase
[作者：Grasselli, A; Nanni, S; Colussi, C; Aiello, A; Benvenuti, V; Ragone, G; Moretti, F; Sacchi, A; Bacchetti, S; Gaetano, C; Capogrossi, MC; Pontecorvi, A; Farsetti, A,期刊：Circulation Research, 页码：34-42 , 文章类型： Article，,卷期：2008年103-1]
- We report that in endothelial cells, the angiogenic effect of 17 beta-estradiol (E2) is inhibited by the estrogen receptor (ER) antagonist ICI or the NO synthase (NOS) inhibitor 7-nitroindazole via downregulation of hTER...
- Heparan sulfate in perlecan promotes mouse atherosclerosis - Roles in lipid permeability, lipid retention, and smooth muscle cell proliferation
[作者：Tran-Lundmark, K; Tran, PK; Paulsson-Berne, G; Friden, V; Soininen, R; Tryggvason, K; Wight, TN; Kinsella, MG; Boren, J; Hedin, U,期刊：Circulation Research, 页码：43-52 , 文章类型： Article，,卷期：2008年103-1]
- Heparan sulfate (HS) has been proposed to be antiatherogenic through inhibition of lipoprotein retention, inflammation, and smooth muscle cell proliferation. Perlecan is the predominant HS proteoglycan in the artery wall...
- Smooth muscle expression of lipoma preferred partner is mediated by an alternative intronic promoter that is regulated by serum response factor/myocardin
[作者：Petit, MMR; Lindskog, H; Larsson, E; Wasteson, P; Athley, E; Breuer, S; Angstenberger, M; Hertfelder, D; Mattsson, E; Nordheim, A; Nelander, S; Lindahl, P,期刊：Circulation Research, 页码：61-69 , 文章类型： Article，,卷期：2008年103-1]
- Lipoma preferred partner (LPP) was recently recognized as a smooth muscle marker that plays a role in smooth muscle cell migration. In this report, we focus on the transcriptional regulation of the LPP gene. In particula...
- Angiogenic function of prostacyclin biosynthesis in human endothelial progenitor cells
[作者：He, T; Lu, T; d'Uscio, LV; Lam, CF; Lee, HC; Katusic, ZS,期刊：Circulation Research, 页码：80-88 , 文章类型： Article，,卷期：2008年103-1]
- The role of prostaglandin production in the control of regenerative function of endothelial progenitor cells (EPCs) has not been studied. We hypothesized that activation of cyclooxygenase (COX) enzymatic activity and the...
- Local activation or implantation of cardiac progenitor cells rescues scarred infarcted myocardium improving cardiac function
[作者：Rota, M; Padin-Iruegas, ME; Misao, Y; De Angelis, A; Maestroni, S; Ferreira-Martins, J; Fiumana, E; Rastaldo, R; Arcarese, ML; Mitchell, TS; Boni, A; Bolli, R; Urbanek, K; Hosoda, T; Anversa, P; Leri, A; Kajstura, J,期刊：Circulation Research, 页码：107-116 , 文章类型： Article，,卷期：2008年103-1]
- Ischemic heart disease is characterized chronically by a healed infarct, foci of myocardial scarring, cavitary dilation, and impaired ventricular performance. These alterations can only be reversed by replacement of scar...
- Myocardial induction of nucleostemin in response to postnatal growth and pathological challenge
[作者：Siddiqi, S; Gude, N; Hosoda, T; Muraski, J; Rubio, M; Emmanuel, G; Fransioli, J; Vitale, S; Parolin, C; D'Amario, D; Schaefer, E; Kajstura, J; Leri, A; Anversa, P; Sussman, MA,期刊：Circulation Research, 页码：89-97 , 文章类型： Article，,卷期：2008年103-1]
- Stem cell - specific proteins and regulatory pathways that determine self-renewal and differentiation have become of fundamental importance in understanding regenerative and reparative processes in the myocardium. One su...
- Mechanisms by which late coronary reperfusion mitigates postinfarction cardiac remodeling
[作者：Nakagawa, M; Takemura, G; Kanamori, H; Goto, K; Maruyama, R; Tsujimoto, A; Ohno, T; Okada, H; Ogino, A; Esaki, M; Miyata, S; Li, L; Ushikoshi, H; Aoyama, T; Kawasaki, M; Nagashima, K; Fujiwara, T; Minatoguchi, S; Fujiwara, H,期刊：Circulation Research, 页码：98-106 , 文章类型： Article，,卷期：2008年103-1]
- Although recanalization of the infarct-related artery late after myocardial infarction (MI) is known to reduce both cardiac remodeling and mortality, the mechanisms responsible are not yet fully understood. We compared i...
- Nrf2 regulates antioxidant gene expression evoked by oxidized phospholipids in endothelial cells and murine arteries in vivo
[作者：Jyrkkanen, HK; Kansanen, E; Inkala, M; Kivela, AM; Hurttila, H; Heinonen, SE; Goldsteins, G; Jauhiainen, S; Tiainen, S; Makkonen, H; Oskolkova, O; Afonyushkin, T; Koistinaho, J; Yamamoto, M; Bochkov, VN; Yla-Herttuala, S; Levonen, AL,期刊：Circulation Research, 页码：E1-E9 , 文章类型： Article，,卷期：2008年103-1]
- Besides their well-characterized proinflammatory and proatherogenic effects, oxidized phospholipids, such as oxPAPC (oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-phosphocholine) have been shown to have beneficial respo...
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