- Mutation in EGFP Domain of LDL Receptor-Related Protein 6 Impairs Cellular LDL Clearance
[作者：Liu, WZ; Mani, S; Davis, NR; Sarrafzadegan, N; Kavathas, PB; Mani, A,期刊：Circulation Research, 页码：1280-U156 , 文章类型： Article，,卷期：2008年103-11]
- Mutation in the EGFP domain of LDL receptor-related protein 6 (LRP6(R611C)) is associated with hypercholesterolemia and early-onset atherosclerosis, but the mechanism by which it causes disease is not known. Cholesterol ...
- Stim1 and Orai1 Mediate CRAC Currents and Store-Operated Calcium Entry Important for Endothelial Cell Proliferation
[作者：Abdullaev, IF; Bisaillon, JM; Potier, M; Gonzalez, JC; Motiani, RK; Trebak, M,期刊：Circulation Research, 页码：1289-U185 , 文章类型： Article，,卷期：2008年103-11]
- Recent breakthroughs in the store-operated calcium (Ca2+) entry (SOCE) pathway have identified Stim1 as the endoplasmic reticulum Ca2+ sensor and Orai1 as the pore forming subunit of the highly Ca2+ -selective CRAC chann...
- Angiotensin(1-7) Blunts Hypertensive Cardiac Remodeling by a Direct Effect on the Heart
[作者：Mercure, C; Yogi, A; Callera, GE; Aranha, AB; Bader, M; Ferreira, AJ; Santos, RAS; Walther, T; Touyz, RM; Reudelhuber, TL,期刊：Circulation Research, 页码：1319-U254 , 文章类型： Article，,卷期：2008年103-11]
- Angiotensin-converting enzyme 2 (ACE2) converts the vasopressor angiotensin II (Ang II) into angiotensin (1-7) [Ang(1-7)], a peptide reported to have vasodilatory and cardioprotective properties. Inactivation of the ACE2...
- Lats2 Is a Negative Regulator of Myocyte Size in the Heart
[作者：Matsui, Y; Nakano, N; Shao, D; Gao, SM; Luo, WT; Hong, C; Zhai, PY; Holle, E; Yu, XZ; Yabuta, N; Tao, WF; Wagner, T; Nojima, H; Sadoshima, J,期刊：Circulation Research, 页码：1309-U243 , 文章类型： Article，,卷期：2008年103-11]
- Mammalian sterile 20-like kinase (Mst) 1 plays an important role in mediating apoptosis and inhibiting hypertrophy in the heart. Because Hippo, a Drosophila homolog of Mst1, forms a signaling complex with Warts, a serine...
- Sustained Persistence of Transplanted Proangiogenic Cells Contributes to Neovascularization and Cardiac Function After Ischemia
[作者：Ziebart, T; Yoon, CH; Trepels, T; Wietelmann, A; Braun, T; Kiessling, F; Stein, S; Grez, M; Ihling, C; Muhly-Reinholz, M; Carmona, G; Urbich, C; Zeiher, AM; Dimmeler, S,期刊：Circulation Research, 页码：1327-U275 , 文章类型： Article，,卷期：2008年103-11]
- Circulating blood-derived vasculogenic cells improve neovascularization of ischemic tissue by a broad repertoire of potential therapeutic actions. Whereas initial studies documented that the cells incorporate and differe...
- Role of Kinin B-2 Receptor Signaling in the Recruitment of Circulating Progenitor Cells With Neovascularization Potential
[作者：Krankel, N; Katare, RG; Siragusa, M; Barcelos, LS; Campagnolo, P; Mangialardi, G; Fortunato, O; Spinetti, G; Tran, N; Zacharowski, K; Wojakowski, W; Mroz, I; Herman, A; Fox, JEM; MacDonald, PE; Schanstra, JP; Bascands, JL; Ascione, R; Angelini, G; Emanueli, C; Madeddu, P,期刊：Circulation Research, 页码：1335-U312 , 文章类型： Article，,卷期：2008年103-11]
- Reduced migratory function of circulating angiogenic progenitor cells (CPCs) has been associated with impaired neovascularization in patients with cardiovascular disease (CVD). Previous findings underline the role of the...
- Heme Oxygenase-1 Regulates Cardiac Mitochondrial Biogenesis via Nrf2-Mediated Transcriptional Control of Nuclear Respiratory Factor-1
[作者：Piantadosi, CA; Carraway, MS; Babiker, A; Suliman, HB,期刊：Circulation Research, 页码：1232-U60 , 文章类型： Article，,卷期：2008年103-11]
- Heme oxygenase (HO)-1 is a protective antioxidant enzyme that prevents cardiomyocyte apoptosis, for instance, during progressive cardiomyopathy. Here we identify a fundamental aspect of the HO-1 protection mechanism by d...
- Mesencephalic Astrocyte-Derived Neurotrophic Factor Is an Ischemia-Inducible Secreted Endoplasmic Reticulum Stress Response Protein in the Heart
[作者：Tadimalla, A; Belmont, PJ; Thuerauf, DJ; Glassy, MS; Martindale, JJ; Gude, N; Sussman, MA; Glembotski, CC,期刊：Circulation Research, 页码：1249-1258 , 文章类型： Article，,卷期：2008年103-11]
- The endoplasmic reticulum (ER) stress response (ERSR) is activated when folding of nascent proteins in the ER lumen is impeded. Myocardial ischemia was recently shown to activate the ERSR; however, the role of this compl...
- Activation of Histone Deacetylase 2 by Inducible Heat Shock Protein 70 in Cardiac Hypertrophy
[作者：Kee, HJ; Eom, GH; Joung, H; Shin, S; Kim, JR; Cho, YK; Choe, N; Sim, BW; Jo, D; Jeong, MH; Kim, KK; Seo, JS; Kook, H,期刊：Circulation Research, 页码：1259-U120 , 文章类型： Article，,卷期：2008年103-11]
- Diverse cardiac diseases induce cardiac hypertrophy, which leads to dilatation and heart failure. We previously reported that hypertrophy can be blocked by class I histone deacetylase (HDAC) inhibitor, which prompted us ...
- Heat Shock Protein 20 Interacting With Phosphorylated Akt Reduces Doxorubicin-Triggered Oxidative Stress and Cardiotoxicity
[作者：Fan, GC; Zhou, XY; Wang, XH; Song, GJ; Qian, J; Nicolaou, P; Chen, GL; Ren, XP; Kranias, EG,期刊：Circulation Research, 页码：1270-U143 , 文章类型： Article，,卷期：2008年103-11]
- Doxorubicin (DOX) is a widely used antitumor drug, but its application is limited because of its cardiotoxic side effects. Heat shock protein (Hsp) 20 has been recently shown to protect cardiomyocytes against apoptosis, ...
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