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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共19条记录   The dynamic Mu transpososome: MuB activation prevents disintegration [作者：Lemberg, KM; Schweidenback, CTH; Baker, TA,期刊：Journal of Molecular Biology, 页码：1158-1171 , 文章类型： Article，,卷期：2007年374-5] DNA transposases use a single active center to sequentially cleave the transposable element DNA and join this DNA to a target site. Recombination requires controlled conformational changes within the transposase to ensur... The heterodimeric primase from the euryarchaeon Pyrococcus abyssi: A multifunctional enzyme for initiation and repair? [作者：Le Breton, M; Henneke, G; Norais, C; Flament, D; Myllykallio, H; Querellou, J; Raffin, JP,期刊：Journal of Molecular Biology, 页码：1172-1185 , 文章类型： Article，,卷期：2007年374-5] We report on the characterization of the DNA primase complex of the hyperthermophilic archaeon Pyrococcus abyssi (Pab). The Pab DNA primase complex is composed of the proteins Pabp41 and Pabp46, which show sequence simil... Haloferax volcanii AglB and AglD are involved in N-glycosylation of the S-layer glycoprotein and proper assembly of the surface layer [作者：Abu-Qarn, M; Yurist-Doutsch, S; Giordano, A; Trauner, A; Morris, HR; Hitchen, P; Medalia, O; Dell, A; Eichler, J,期刊：Journal of Molecular Biology, 页码：1224-1236 , 文章类型： Article，,卷期：2007年374-5] In this study, the effects of deleting two genes previously implicated in Haloferax volcanii N-glycosylation on the assembly and attachment of a novel Asn-linked pentasaccharide decorating the H. volcanii S-layer glycopr... Crystal structure of the ligand-binding protein EhuB from Sinorhizobium meliloti reveals substrate recognition of the compatible solutes ectoine and hydroxyectoine [作者：Hanekop, N; Hoing, M; Sohn-Boesser, L; Jebbar, M; Schmitt, L; Bremer, E,期刊：Journal of Molecular Biology, 页码：1237-1250 , 文章类型： Article，,卷期：2007年374-5] In microorganisms, members of the binding-protein-dependent ATP-binding cassette transporter superfamily constitute an important class of transport systems. Some of them are involved in osmoprotection under hyperosmotic ... Predicting knot or catenane type of site-specific recombination products [作者：Buck, D; Flapan, E,期刊：Journal of Molecular Biology, 页码：1186-1199 , 文章类型： Article，,卷期：2007年374-5] Site-specific recombination on supercoiled circular DNA yields a variety of knotted or catenated products. Here, we present a topological model of this process and characterize all possible products of the most common su... PIAS proteins as repressors of Oct4 function [作者：Tolkunova, E; Malashicheva, A; Parfenov, VN; Sustmann, C; Grosschedl, R; Tomilin, A,期刊：Journal of Molecular Biology, 页码：1200-1212 , 文章类型： Article，,卷期：2007年374-5] The POU domain transcription factor Oct4 plays essential functions in the maintenance of pluripotent embryonic and germ cells of mammals. Molecular mechanisms of Oct4 action remain poorly understood. To isolate modulator... Distribution plasticity of the human estrogen receptor alpha in live cells: Distinct imaging of consecutively expressed receptors [作者：Pick, H; Jankevics, H; Vogel, H,期刊：Journal of Molecular Biology, 页码：1213-1223 , 文章类型： Article，,卷期：2007年374-5] An amino-terminal fusion of the human estrogen receptor at (ER) with human O-6-alkylguanine-DNA alkyltransferase (AGT) enabled the observation and distinction of consecutively expressed ER populations by sequential pulse... The control of transmembrane helix transverse position in membranes by hydrophilic residues [作者：Krishnakumar, SS; London, E,期刊：Journal of Molecular Biology, 页码：1251-1269 , 文章类型： Article，,卷期：2007年374-5] The ability of hydrophilic residues to shift the transverse position of transmembrane (TM) helices within bilayers was studied in model membrane vesicles. Transverse shifts were detected by fluorescence measurements of t... All-atom simulations of structures and energetics of c-di-GMP-bound and free PleD [作者：Schmid, FFF; Meuwly, M,期刊：Journal of Molecular Biology, 页码：1270-1285 , 文章类型： Article，,卷期：2007年374-5] Cyclic diguanosine monophosphate is a bacterial second messenger involved in a lifestyle switch from single cells to biofilm formation. Atomistic simulations are used to characterize inhibited diguanylate cyclase (DGC) P... Mapping intramolecular interactions between domains in HMGB1 using a tail-truncation approach [作者：Watson, M; Stott, K; Thomas, JO,期刊：Journal of Molecular Biology, 页码：1286-1297 , 文章类型： Article，,卷期：2007年374-5] The mechanism underlying negative regulation of HMGB1-DNA interaction by the acidic C-terminal tail is ill defined. To address this issue, we have devised a novel NMR chemical-shift perturbation mapping strategy to eluci... Crystal structures of the staphylococcal toxin SSL5 in complex with sialyl lewis X reveal a conserved binding site that shares common features with viral and bacterial sialic acid binding proteins [作者：Baker, HM; Basu, I; Chung, MC; Caradoc-Davies, T; Fraser, JD; Baker, EN,期刊：Journal of Molecular Biology, 页码：1298-1308 , 文章类型： Article，,卷期：2007年374-5] Staphylococcus aureus is a significant human pathogen. Among its large repertoire of secreted toxins is a group of staphylococcal superantigen-like proteins (SSLs). These are homologous to superantigens but do not have t... Opsin stability and folding: The role of Cys185 and abnormal disulfide bond formation in the intradiscal domain [作者：McKibbin, C; Toye, AM; Reeves, PJ; Khorana, HG; Edwards, PC; Villa, C; Booth, PJ,期刊：Journal of Molecular Biology, 页码：1309-1318 , 文章类型： Article，,卷期：2007年374-5] The structure in the extracellular, intradiscal domain of rhodopsin surrounding the Cys110-Cys187 disulfide bond has been shown to be important for correct folding of this receptor in vivo. Retinitis pigmentosa misfoldin... Opsin stability and folding: Modulation by phospholipid bicelles [作者：McKibbin, C; Farmer, NA; Jeans, C; Reeves, PJ; Khorana, HG; Wallace, BA; Edwards, PC; Villa, C; Booth, PJ,期刊：Journal of Molecular Biology, 页码：1319-1332 , 文章类型： Article，,卷期：2007年374-5] Integral membrane proteins do not fare well when extracted from biological membranes and are unstable or lose activity in detergents commonly used for structure and function investigations. We show that phospholipid bice... Solution structure of inhibitor-free human metalloelastase (MMP-12) indicates an internal conformational adjustment [作者：Bhaskaran, R; Palmier, MO; Bagegni, NA; Liang, XY; Van Doren, SR,期刊：Journal of Molecular Biology, 页码：1333-1344 , 文章类型： Article，,卷期：2007年374-5] Macrophage metalloelastase or matrix metalloproteinase-12 (MMP-12) appears to exacerbate atherosclerosis, emphysema, aortic aneurysm, rheumatoid arthritis, and inflammatory bowel disease. An inactivating E219A mutation, ... Archaeal Hel308 domain V couples DNA binding to ATP hydrolysis and positions DNA for unwinding over the helicase ratchet [作者：Woodman, IL; Briggs, GS; Bolt, EL,期刊：Journal of Molecular Biology, 页码：1139-1144 , 文章类型： Article，,卷期：2007年374-5] Hel308 and PolQ are paralogues with roles promoting genome stability in archaea and higher eukaryotes. The context in which they act is not clear, although Hel308 helicase from archaea may interact with abnormal replicat... Molecular and functional mapping of EED motifs required for PRC2-Dependent histone methylation [作者：Montgomery, ND; Yee, D; Montgomery, SA; Magnuson, T,期刊：Journal of Molecular Biology, 页码：1145-1157 , 文章类型： Article，,卷期：2007年374-5] Polycomb group proteins represent a conserved family of developmental regulators that mediate heritable transcriptional silencing by modifying chromatin states. One Polycomb group complex, the PRC2 complex, is composed o...