- Sprouty1 Regulates Reversible Quiescence of a Self-Renewing Adult Muscle Stem Cell Pool during Regeneration
[作者:Shea, KL; Xiang, WY; LaPorta, VS; Licht, JD; Keller, C; Basson, MA; Brack, AS,期刊:Cell Stem Cell, 页码:117-129 , 文章类型: Article,,卷期:2010年6-2]
- Satellite cells are skeletal muscle stem cells capable of self-renewal and differentiation after transplantation, but whether they contribute to endogenous muscle fiber repair has been unclear. The transcription factor P...
- Key Roles for Transforming Growth Factor beta in Melanocyte Stem Cell Maintenance
[作者:Nishimura, EK; Suzuki, M; Igras, V; Du, JY; Lonning, S; Miyachi, Y; Roes, J; Beermann, F; Fisher, DE,期刊:Cell Stem Cell, 页码:130-140 , 文章类型: Article,,卷期:2010年6-2]
- Melanocyte stem cells in the bulge area of hair follicles are responsible for hair pigmentation, and defects in them cause hair graying. Here we describe the process of melanocyte stem cell entry into the quiescent state...
- Perivascular Nitric Oxide Activates Notch Signaling and Promotes Stem-like Character in PDGF-Induced Glioma Cells
[作者:Charles, N; Ozawa, T; Squatrito, M; Bleau, AM; Brennan, CW; Hambardzumyan, D; Holland, EC,期刊:Cell Stem Cell, 页码:141-152 , 文章类型: Article,,卷期:2010年6-2]
- eNOS expression is elevated in human glioblastomas and correlated with increased tumor growth and aggressive character. We investigated the potential role of nitric oxide (NO) activity in the perivascular niche (PVN) usi...
- Polycomb-like 2 Associates with PRC2 and Regulates Transcriptional Networks during Mouse Embryonic Stem Cell Self-Renewal and Differentiation
[作者:Walker, E; Chang, WY; Hunkapiller, J; Cagney, G; Garcha, K; Torchia, J; Krogan, NJ; Reiter, JF; Stanford, WL,期刊:Cell Stem Cell, 页码:153-166 , 文章类型: Article,,卷期:2010年6-2]
- Polycomb group (PcG) proteins are conserved epigenetic transcriptional repressors that control numerous developmental gene expression programs and have recently been implicated in modulating embryonic stem cell (ESC) fat...
- The Nuclear Receptor Nr5a2 Can Replace Oct4 in the Reprogramming of Murine Somatic Cells to Pluripotent Cells
[作者:Heng, JCD; Feng, B; Han, JY; Jiang, JM; Kraus, P; Ng, JH; Orlov, YL; Huss, M; Yang, L; Lufkin, T; Lim, B; Ng, HH,期刊:Cell Stem Cell, 页码:167-174 , 文章类型: Article,,卷期:2010年6-2]
- Somatic cells can be reprogrammed to induced pluripotent stem cells (iPSGs) with the introduction of Oct4, Sox2, Klf4, and c-Myc. Among these four factors, Oct4 is critical in inducing pluripotency because no transcripti...
- Spindle Orientation Bias in Gut Epithelial Stem Cell Compartments Is Lost in Precancerous Tissue
[作者:Quyn, AJ; Appleton, PL; Carey, FA; Steele, RJC; Barker, N; Clevers, H; Ridgway, RA; Sansom, OJ; Nathke, IS,期刊:Cell Stem Cell, 页码:175-181 , 文章类型: Article,,卷期:2010年6-2]
- The importance of asymmetric divisions for stem cell function and maintenance is well established in the developing nervous system and the skin; however, its role in gut epithelium and its importance for tumorigenesis is...
- NO Signals from the Cancer Stem Cell Niche
[作者:Seoane, J,期刊:Cell Stem Cell, 页码:97-98 , 文章类型: Editorial Material,,卷期:2010年6-2]
- Characterization of signaling pathways that control cancer stem cells may lead to more effective treatments against cancer. In this issue of Cell Stem Cell, a study by Charles et al. (2010) identifies the NO and Notch pa...
- Stem Cells and the Niche: A Dynamic Duo
[作者:Voog, J; Jones, DL,期刊:Cell Stem Cell, 页码:103-115 , 文章类型: Review,,卷期:2010年6-2]
- Stem cell niches are dynamic microenvironments that balance stem cell activity to maintain tissue homeostasis and repair throughout the lifetime of an organism. The development of strategies to monitor and perturb niche ...
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