- A Murine ESC-like State Facilitates Transgenesis and Homologous Recombination in Human Pluripotent Stem Cells
[作者:Buecker, C; Chen, HH; Polo, JM; Daheron, L; Bu, L; Barakat, TS; Okwieka, P; Porter, A; Gribnau, J; Hochedlinger, K; Geijsen, N,期刊:Cell Stem Cell, 页码:535-546 , 文章类型: Article,,卷期:2010年6-6]
Murine pluripotent stem cells can exist in two functionally distinct states, LIF-dependent embryonic stem cells (ESCs) and bFGF-dependent epiblast stem cells (EpiSCs). However, human pluripotent cells so far seemed to...
- ESCs Require PRC2 to Direct the Successful Reprogramming of Differentiated Cells toward Pluripotency
[作者:Pereira, CF; Piccolo, FM; Tsubouchi, T; Sauer, S; Ryan, NK; Bruno, L; Landeira, D; Santos, J; Banito, A; Gil, J; Koseki, H; Merkenschlager, M; Fisher, AG,期刊:Cell Stem Cell, 页码:547-556 , 文章类型: Article,,卷期:2010年6-6]
- Embryonic stem cells (ESCs) are pluripotent, self-renewing, and have the ability to reprogram differentiated cell types to pluripotency upon cellular fusion. Polycomb-group (PcG) proteins are important for restraining th...
- CNS-Resident Glial Progenitor/Stem Cells Produce Schwann Cells as well as Oligodendrocytes during Repair of CNS Demyelination
[作者:Zawadzka, M; Rivers, LE; Fancy, SPJ; Zhao, C; Tripathi, R; Jamen, F; Young, K; Goncharevich, A; Pohl, H; Rizzi, M; Rowitch, DH; Kessaris, N; Suter, U; Richardson, WD; Franklin, RJM,期刊:Cell Stem Cell, 页码:578-590 , 文章类型: Article,,卷期:2010年6-6]
- After central nervous system (CNS) demyelination such as occurs during multiple sclerosis there is often spontaneous regeneration of myelin sheaths, mainly by oligodendrocytes but also by Schwann cells. The origins of th...
- Wilms Tumor Chromatin Profiles Highlight Stem Cell Properties and a Renal Developmental Network
[作者:Aiden, AP; Rivera, MN; Rheinbay, E; Ku, MC; Coffman, EJ; Truong, TT; Vargas, SO; Lander, ES; Haber, DA; Bernstein, BE,期刊:Cell Stem Cell, 页码:591-602 , 文章类型: Article,,卷期:2010年6-6]
- Wilms tumor is the most common pediatric kidney cancer. To identify transcriptional and epigenetic mechanisms that drive this disease, we compared genome-wide chromatin profiles of Wilms tumors, embryonic stem cells (ESC...
- A Subpopulation of CD26(+) Cancer Stem Cells with Metastatic Capacity in Human Colorectal Cancer
[作者:Pang, R; Law, WL; Chu, ACY; Poon, JT; Lam, CSC; Chow, AKM; Ng, L; Cheung, LWH; Lan, XR; Lan, HY; Tan, VPY; Yau, TC; Poon, RT; Wong, BCY,期刊:Cell Stem Cell, 页码:603-615 , 文章类型: Article,,卷期:2010年6-6]
- Recent evidence suggests that a subpopulation of cancer cells, cancer stem cells (CSCs), is responsible for tumor growth in colorectal cancer. However, the role of CSCs in colorectal cancer metastasis is unclear. Here, w...
- Multiple, Interconvertible States of Human Pluripotent Stem Cells
[作者:Kerr, CL; Cheng, LZ,期刊:Cell Stem Cell, 页码:497-499 , 文章类型: Editorial Material,,卷期:2010年6-6]
- Three recent studies, including Buecker et al. (2010), in this issue of Cell Stem Cell, report that human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) can exist in distinct but interconvertible ...
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