- Restoration of muscle fibers and satellite cells after isogenic MSC transplantation with microdystrophin gene delivery
[作者:Feng, SW; Chen, F; Cao, JQ; Yu, MJ; Liang, YY; Song, XM; Zhang, C,期刊:Biochemical and Biophysical Research Communications, 页码:1-6 , 文章类型: Article,,卷期:2012年419-1]
- Duchenne muscular dystrophy is the most prevalent inheritable muscle disease. Transplantation of autologous stem cells with gene direction is an ideal therapeutic approach for the disease. The current study aimed to inve...
- Human cord blood-derived multipotent stem cells (CB-SCs) treated with all-trans-retinoic acid (ATRA) give rise to dopamine neurons
[作者:Li, XH; Li, H; Bi, JF; Chen, YN; Jain, S; Zhao, Y,期刊:Biochemical and Biophysical Research Communications, 页码:110-116 , 文章类型: Article,,卷期:2012年419-1]
- Parkinson's disease (PD) results from the chronic degeneration of dopaminergic neurons. A replacement for these neurons has the potential to provide a clinical cure and/or lasting treatment for symptoms of the disease. H...
- Clinical response to chemotherapy in locally advanced breast cancer was not associated with several polymorphisms in detoxification enzymes and DNA repair genes
[作者:Saadat, M; Khalili, M; Nasiri, M; Rajaei, M; Omidvari, S; Saadat, I,期刊:Biochemical and Biophysical Research Communications, 页码:117-119 , 文章类型: Article,,卷期:2012年419-1]
- The main aim of the present study was to investigate the association between several genetic polymorphisms (in glutathione S-transferase members and DNA repair genes) and clinical response to chemotherapy in locally adva...
- Effect of influenza A virus non-structural protein 1(NS1) on a mouse model of diabetes mellitus induced by Streptozotocin
[作者:Pei, DC; Dai, J; Kuang, Y; Wang, H; Ren, LF; Shao, JJ; Zuo, B; Li, S; Jiang, ZH; Li, MY,期刊:Biochemical and Biophysical Research Communications, 页码:120-125 , 文章类型: Article,,卷期:2012年419-1]
- Type 1 diabetes (T1D) is a chronic autoimmune disease caused by proinflammatory autoreactive T cells that mediate the selective destruction of insulin-producing beta cells via both direct and indirect mechanisms. Many im...
- Transplantation of induced pluripotent stem cell-derived neurospheres for peripheral nerve repair
[作者:Uemura, T; Takamatsu, K; Ikeda, M; Okada, M; Kazuki, K; Ikada, Y; Nakamura, H,期刊:Biochemical and Biophysical Research Communications, 页码:130-135 , 文章类型: Article,,卷期:2012年419-1]
- In spite of the extensive research using induced pluripotent stem (iPS) cells, the therapeutic potential of iPS cells in the treatment of peripheral nerve injury is largely unknown. In this study, we repaired peripheral ...
- O-linked-N-acetylglucosamine modification of mammalian Notch receptors by an atypical O-GlcNAc transferase Eogt1
[作者:Sakaidani, Y; Ichiyanagi, N; Saito, C; Nomura, T; Ito, M; Nishio, Y; Nadano, D; Matsuda, T; Furukawa, K; Okajima, T,期刊:Biochemical and Biophysical Research Communications, 页码:14-19 , 文章类型: Article,,卷期:2012年419-1]
- O-linked-beta-N-acetylglucosamine (O-GlcNAc) modification is a unique cytoplasmic and nuclear protein modification that is common in nearly all eukaryotes, including filamentous fungi, plants, and animals. We had recentl...
- Methionine sulfoxide reductase B in the endoplasmic reticulum is critical for stress resistance and aging in Drosophila
[作者:Lim, DH; Han, JY; Kim, JR; Lee, YS; Kim, HY,期刊:Biochemical and Biophysical Research Communications, 页码:20-26 , 文章类型: Article,,卷期:2012年419-1]
- Methionine sulfoxide reductase B (MsrB) is an enzyme that repairs oxidatively damaged proteins by specifically reducing methionine-R-sulfoxide back to methionine. Three MsrBs, localized in different cellular compartments...
- Engineering fibrotic tissue in pancreatic cancer: A novel three-dimensional model to investigate nanoparticle delivery
[作者:Hosoya, H; Kadowaki, K; Matsusaki, M; Cabral, H; Nishihara, H; Ijichi, H; Koike, K; Kataoka, K; Miyazono, K; Akashi, M; Kano, MR,期刊:Biochemical and Biophysical Research Communications, 页码:32-37 , 文章类型: Article,,卷期:2012年419-1]
- Pancreatic cancer contains both fibrotic tissue and tumor cells with embedded vasculature. Therefore anti-cancer nanoparticles need to extravasate from tumor vasculature and permeate thick fibrotic tissue to target tumor...
- The GTPase TcRjl of the human pathogen Trypanosoma cruzi is involved in the cell growth and differentiation
[作者:dos Santos, GRRM; Nepomuceno-Silva, JL; de Melo, LDB; Meyer-Fernandes, JR; Salmon, D; Azevedo-Pereira, RL; Lopes, UG,期刊:Biochemical and Biophysical Research Communications, 页码:38-42 , 文章类型: Article,,卷期:2012年419-1]
- The protozoan parasite Trypanosoma cruzi, the etiological agent of Chagas Disease, undergoes through a complex life cycle where rounds of cell division and differentiation occur initially in the gut of triatominae vector...
- Covalently linking the Escherichia coli global anaerobic regulator FNR in tandem allows it to function as an oxygen stable dimer
[作者:Shan, Y; Pan, Q; Liu, JY; Huang, FJ; Sun, HZ; Nishino, K; Yan, AX,期刊:Biochemical and Biophysical Research Communications, 页码:43-48 , 文章类型: Article,,卷期:2012年419-1]
- The anaerobic global regulator FNR from Escherichia coli is a [4Fe-4S](2+) cluster containing, O-2 labile dimer that plays an important role in adapting the bacterium to its anaerobic lifestyle. Although functional signi...
- Inhibition of JNK/dFOXO pathway and caspases rescues neurological impairments in Drosophila Alzheimer's disease model
[作者:Hong, YK; Lee, S; Park, SH; Lee, JH; Han, SY; Kim, ST; Kim, YK; Jeon, S; Koo, BS; Cho, KS,期刊:Biochemical and Biophysical Research Communications, 页码:49-53 , 文章类型: Article,,卷期:2012年419-1]
- Amyloid-beta-42 (A beta 42) has been implicated in the pathogenesis of Alzheimer's disease (AD). Neuronal A beta 42 expression induces apoptosis and decreases survival and locomotive activity in Drosophila. However, the ...
- Biodistribution and stability of CdSe core quantum dots in mouse digestive tract following per os administration: Advantages of double polymer/silica coated nanocrystals
[作者:Loginova, YF; Dezhurov, SV; Zherdeva, VV; Kazachkina, NI; Wakstein, MS; Savitsky, AP,期刊:Biochemical and Biophysical Research Communications, 页码:54-59 , 文章类型: Article,,卷期:2012年419-1]
- CdSe-core, ZnS-capped semiconductor quantum dots (QDs) are of great potential for biomedical applications. However, applications in the gastrointestinal tract for in vivo imaging and therapeutic purposes are hampered by ...
- Properties of an 'LNA'-modified ricin RNA aptamer
[作者:Forster, C; Zydek, M; Rothkegel, M; Wu, ZY; Gallin, C; Gessner, R; Lisdat, F; Furste, JP,期刊:Biochemical and Biophysical Research Communications, 页码:60-65 , 文章类型: Article,,卷期:2012年419-1]
- 'Locked nucleic acids' (LNAs) are sugar modified nucleic acids containing the 2'-O-4'C-methylene-beta-D-ribofuranoses. The substitution of RNAs with LNAs leads to an enhanced thermostability. Aptamers are nucleic acids, ...
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