- ePMV Embeds Molecular Modeling into Professional Animation Software Environments
[作者:Johnson, GT; Autin, L; Goodsell, DS; Sanner, MF; Olson, AJ,期刊:Structure, 页码:293-303 , 文章类型: Article,,卷期:2011年19-3]
- Increasingly complex research has made it more difficult to prepare data for publication, education, and outreach. Many scientists must also wade through black-box code to interface computational algorithms from diverse ...
- Two Structural and Functional Domains of MESD Required for Proper Folding and Trafficking of LRP5/6
[作者:Chen, JL; Liu, CC; Li, QQ; Nowak, C; Bu, GJ; Wang, JJ,期刊:Structure, 页码:313-323 , 文章类型: Article,,卷期:2011年19-3]
- How the endoplasmic reticulum (ER) folding machinery coordinates general and specialized chaperones during protein translation and folding remains an important unanswered question. Here, we show two structural domains in...
- The Structure of MESD45-184 Brings Light into the Mechanism of LDLR Family Folding
[作者:Kohler, C; Lighthouse, JK; Werther, T; Andersen, OM; Diehl, A; Schmieder, P; Du, JG; Holdener, BC; Oschkinat, H,期刊:Structure, 页码:337-348 , 文章类型: Article,,卷期:2011年19-3]
- Mesoderm development (MESD) is a 224 amino acid mouse protein that acts as a molecular chaperone for the low-density lipoprotein receptor (LDLR) family. Here, we provide evidence that the region 45-184 of MESD is essenti...
- The Contribution of Entropy, Enthalpy, and Hydrophobic Desolvation to Cooperativity in Repeat-Protein Folding
[作者:Aksel, T; Majumdar, A; Barrick, D,期刊:Structure, 页码:349-360 , 文章类型: Article,,卷期:2011年19-3]
- Cooperativity is a defining feature of protein folding, but its thermodynamic and structural origins are not completely understood. By constructing consensus ankyrin repeat protein arrays that have nearly identical seque...
- The Mechanisms of HAMP-Mediated Signaling in Transmembrane Receptors
[作者:Ferris, HU; Dunin-Horkawicz, S; Mondejar, LG; Hulko, M; Hantke, K; Martin, J; Schultz, JE; Zeth, K; Lupas, AN; Coles, M,期刊:Structure, 页码:378-385 , 文章类型: Article,,卷期:2011年19-3]
- HAMP domains mediate signal transduction in over 7500 enzyme-coupled receptors represented in all kingdoms of life. The HAMP domain of the putative archaeal receptor Af1503 has a parallel, dimeric, four-helical coiled co...
- X-ray Crystal Structure of the UCS Domain-Containing UNC-45 Myosin Chaperone from Drosophila melanogaster
[作者:Lee, CF; Hauenstein, AV; Fleming, JK; Gasper, WC; Engelke, V; Sankaran, B; Bernstein, SI; Huxford, T,期刊:Structure, 页码:397-408 , 文章类型: Article,,卷期:2011年19-3]
- UCS proteins, such as UNC-45, influence muscle contraction and other myosin-dependent motile processes. We report the first X-ray crystal structure of a UCS domain-containing protein, the UNC-45 myosin chaperone from Dro...
- Intrinsic Bending of Microtubule Protofilaments
[作者:Grafmuller, A; Voth, GA,期刊:Structure, 页码:409-417 , 文章类型: Article,,卷期:2011年19-3]
- The complex polymerization dynamics of the microtubule (MT) plus end are closely linked to the hydrolysis of the GTP nucleotide bound to the beta-tubulin. The destabilization is thought to be associated with the conforma...
- Interferon-Inducible Protein 16: Insight into the Interaction with Tumor Suppressor p53
[作者:Liao, JCC; Lam, R; Brazda, V; Duan, SL; Ravichandran, M; Ma, J; Xiao, T; Tempel, W; Zuo, XB; Wang, YX; Chirgadze, NY; Arrowsmith, CH,期刊:Structure, 页码:418-429 , 文章类型: Article,,卷期:2011年19-3]
- IFI16 is a member of the interferon-inducible HIN-200 family of nuclear proteins. It has been implicated in transcriptional regulation by modulating protein-protein interactions with p53 tumor suppressor protein and othe...
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