- Clarithromycin attenuates myocardial ischemia-reperfusion injury
[作者:Nakajima, T; Hishikari, K; Ogawa, M; Watanabe, R; Suzuki, J; Nagashima, A; Masumura, M; Takayama, K; Hirata, Y; Nagai, R; Isobe, M,期刊:Expert Opinion on Therapeutic Targets, 页码:881-893 , 文章类型: Article,,卷期:2010年14-9]
- Background: MMP activity is upregulated in the heart after myocardial ischemia reperfusion, and its activation contributes to the changes in left ventricular (LV) dysfunction. A major macrolide antibiotic, clarithromycin...
- CCR6 as a possible therapeutic target in psoriasis
[作者:Hedrick, MN; Lonsdorf, AS; Hwang, ST; Farber, JM,期刊:Expert Opinion on Therapeutic Targets, 页码:911-922 , 文章类型: Review,,卷期:2010年14-9]
- Importance of the field: Psoriasis is a common, chronic autoimmune disease of the skin. Despite a number of effective treatments, new therapies are needed with enhanced efficacy, safety and convenience. Chemokine recepto...
- TRPM2 channel properties, functions and therapeutic potentials
[作者:Jiang, LH; Yang, W; Zou, J; Beech, DJ,期刊:Expert Opinion on Therapeutic Targets, 页码:973-988 , 文章类型: Review,,卷期:2010年14-9]
- Importance of the field: Oxidative stress, through production of reactive oxygen species, triggers disturbance in intracellular calcium [Ca2+](i) homeostasis, which has been identified as an important causative factor in...
|