- A Lipid Profile Typifies the Beijing Strains of Mycobacterium tuberculosis IDENTIFICATION OF A MUTATION RESPONSIBLE FOR A MODIFICATION OF THE STRUCTURES OF PHTHIOCEROL DIMYCOCEROSATES AND PHENOLIC GLYCOLIPIDS
[作者:Huet, G; Constant, P; Malaga, W; Laneelle, MA; Kremer, K; Van Soolingen, D; Daffe, M; Guilhot, C,期刊:Journal of Biological Chemistry, 页码:27101-27113 , 文章类型: Article,,卷期:2009年284-40]
- The Mycobacterium tuberculosis Beijing strains are a family highly prevalent in Asia and have recently spread worldwide, causing a number of epidemics, suggesting that they express virulence factors not found in other M....
- Cardiolipin Molecular Species with Shorter Acyl Chains Accumulate in Saccharomyces cerevisiae Mutants Lacking the Acyl Coenzyme A-binding Protein Acb1p NEW INSIGHTS INTO ACYL CHAIN REMODELING OF CARDIOLIPIN
[作者:Rijken, PJ; Houtkooper, RH; Akbari, H; Brouwers, JF; Koorengevel, MC; de Kruijff, B; Frentzen, M; Vaz, FM; de Kroon, AIPM,期刊:Journal of Biological Chemistry, 页码:27609-27619 , 文章类型: Article,,卷期:2009年284-40]
- The function of the mitochondrial phospholipid cardiolipin (CL) is thought to depend on its acyl chain composition. The present study aims at a better understanding of the way the CL species profile is established in Sac...
- The Linker Region in Receptor Guanylyl Cyclases Is a Key Regulatory Module MUTATIONAL ANALYSIS OF GUANYLYL CYCLASE C
[作者:Saha, S; Biswas, KH; Kondapalli, C; Isloor, N; Visweswariah, SS,期刊:Journal of Biological Chemistry, 页码:27135-27145 , 文章类型: Article,,卷期:2009年284-40]
- Receptor guanylyl cyclases are multidomain proteins, and ligand binding to the extracellular domain increases the levels of intracellular cGMP. The intracellular domain of these receptors is composed of a kinase homology...
- MCP-1 (Monocyte Chemotactic Protein-1)-induced Protein, a Recently Identified Zinc Finger Protein, Induces Adipogenesis in 3T3-L1 Pre-adipocytes without Peroxisome Proliferator-activated Receptor gamma
[作者:Younce, CW; Azfer, A; Kolattukudy, PE,期刊:Journal of Biological Chemistry, 页码:27620-27628 , 文章类型: Article,,卷期:2009年284-40]
- Adipogenesis is a key differentiation process relevant to obesity and associated diseases such as type 2 diabetes. This process involves temporally regulated genes controlled by a set of transcription factors, CCAAT/enha...
- Syndecan-2 Regulates the Migratory Potential of Melanoma Cells
[作者:Lee, JH; Park, H; Chung, H; Choi, S; Kim, Y; Yoo, H; Kim, TY; Hann, HJ; Seong, I; Kim, J; Kang, KG; Han, IO; Oh, ES,期刊:Journal of Biological Chemistry, 页码:27167-27175 , 文章类型: Article,,卷期:2009年284-40]
- Syndecan-2, a transmembrane heparan sulfate proteoglycan, is a critical mediator in the tumorigenesis of colon carcinoma cells. We explored the function of syndecan-2 in melanoma, one of the most invasive types of cancer...
- Mechanism of Cyclizing NAD to Cyclic ADP-ribose by ADP-ribosyl Cyclase and CD38
[作者:Graeff, R; Liu, Q; Kriksunov, IA; Kotaka, M; Oppenheimer, N; Hao, Q; Lee, HC,期刊:Journal of Biological Chemistry, 页码:27629-27636 , 文章类型: Article,,卷期:2009年284-40]
- Mammalian CD38 and its Aplysia homolog, ADP-ribosyl cyclase (cyclase), are two prominent enzymes that catalyze the synthesis and hydrolysis of cyclic ADP-ribose (cADPR), a Ca2+ messenger molecule responsible for regulati...
- Structural Basis for Enzymatic Evolution from a Dedicated ADP-ribosyl Cyclase to a Multifunctional NAD Hydrolase
[作者:Liu, Q; Graeff, R; Kriksunov, IA; Jiang, H; Zhang, B; Oppenheimer, N; Lin, HN; Potter, BVL; Lee, HC; Hao, Q,期刊:Journal of Biological Chemistry, 页码:27637-27645 , 文章类型: Article,,卷期:2009年284-40]
- Cyclic ADP-ribose (cADPR) is a universal calcium messenger molecule that regulates many physiological processes. The production and degradation of cADPR are catalyzed by a family of related enzymes, including the ADP-rib...
- Critical Role of Heparin Binding Domains of Ameloblastin for Dental Epithelium Cell Adhesion and Ameloblastoma Proliferation
[作者:Sonoda, A; Iwamoto, T; Nakamura, T; Fukumoto, E; Yoshizaki, K; Yamada, A; Arakaki, M; Harada, H; Nonaka, K; Nakamura, S; Yamada, Y; Fukumoto, S,期刊:Journal of Biological Chemistry, 页码:27176-27184 , 文章类型: Article,,卷期:2009年284-40]
- AMBN (ameloblastin) is an enamel matrix protein that regulates cell adhesion, proliferation, and differentiation of ameloblasts. In AMBN-deficient mice, ameloblasts are detached from the enamel matrix, continue to prolif...
- Regulation of Expression of the Rat Orthologue of Mouse Double Minute 2 (MDM2) by H2O2-induced Oxidative Stress in Neonatal Rat Cardiac Myocytes
[作者:Pikkarainen, S; Kennedy, RA; Marshall, AK; Tham, EL; Lay, K; Kriz, TA; Handa, BS; Clerk, A; Sugden, PH,期刊:Journal of Biological Chemistry, 页码:27195-27210 , 文章类型: Article,,卷期:2009年284-40]
- The Mdm2 ubiquitin ligase is an important regulator of p53 abundance and p53-dependent apoptosis. Mdm2 expression is frequently regulated by a p53 Mdm2 autoregulatory loop whereby p53 stimulates Mdm2 expression and hence...
- The Clavesin Family, Neuron-specific Lipid-and Clathrin-binding Sec14 Proteins Regulating Lysosomal Morphology
[作者:Katoh, Y; Ritter, B; Gaffry, T; Blondeau, F; Honing, S; McPherson, PS,期刊:Journal of Biological Chemistry, 页码:27646-27654 , 文章类型: Article,,卷期:2009年284-40]
- Clathrin-coated vesicles (CCVs) originating from the trans-Golgi network (TGN) provide a major transport pathway from the secretory system to endosomes/lysosomes. Herein we describe paralogous Sec14 domain-bearing protei...
- Structural Basis for the Kexin-like Serine Protease from Aeromonas sobria as Sepsis-causing Factor
[作者:Kobayashi, H; Utsunomiya, H; Yamanaka, H; Sei, Y; Katunuma, N; Okamoto, K; Tsuge, H,期刊:Journal of Biological Chemistry, 页码:27655-27663 , 文章类型: Article,,卷期:2009年284-40]
- The anaerobic bacterium Aeromonas sobria is known to cause potentially lethal septic shock. We recently proposed that A. sobria serine protease (ASP) is a sepsis-related factor that induces vascular leakage, reductions i...
- Autophagy Regulates Pancreatic Beta Cell Death in Response to Pdx1 Deficiency and Nutrient Deprivation
[作者:Fujimoto, K; Hanson, PT; Tran, H; Ford, EL; Han, ZQ; Johnson, JD; Schmidt, RE; Green, KG; Wice, BM; Polonsky, KS,期刊:Journal of Biological Chemistry, 页码:27664-27673 , 文章类型: Article,,卷期:2009年284-40]
- There are three types of cell death; apoptosis, necrosis, and autophagy. The possibility that activation of the macroautophagy (autophagy) pathway may increase beta cell death is addressed in this study. Increased autoph...
- The Cytoplasmic Peptidase DPP9 Is Rate-limiting for Degradation of Proline-containing Peptides
[作者:Geiss-Friedlander, R; Parmentier, N; Moller, U; Urlaub, H; Van den Eynde, BJ; Melchior, F,期刊:Journal of Biological Chemistry, 页码:27211-27219 , 文章类型: Article,,卷期:2009年284-40]
- Protein degradation is an essential process that continuously takes place in all living cells. Regulated degradation of most cellular proteins is initiated by proteasomes, which produce peptides of varying length. These ...
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