- Viral Interferon Regulatory Factors Are Critical for Delay of the Host Immune Response against Rhesus Macaque Rhadinovirus Infection
[作者:Robinson, BA; O'Connor, MA; Li, H; Engelmann, F; Poland, B; Grant, R; DeFilippis, V; Estep, RD; Axthelm, MK; Messaoudi, I; Wong, SW,期刊:Journal of virology, 页码:2769-2779 , 文章类型: Article,,卷期:2012年86-5]
- Kaposi's sarcoma-associated herpesvirus (KSHV) and the closely related gamma-2 herpesvirus rhesus macaque (RM) rhadinovirus (RRV) are the only known viruses to encode viral homologues of the cellular interferon (IFN) reg...
- Polymorphic Integrations of an Endogenous Gammaretrovirus in the Mule Deer Genome
[作者:Elleder, D; Kim, O; Padhi, A; Bankert, JG; Simeonov, I; Schuster, SC; Wittekindt, NE; Motameny, S; Poss, M,期刊:Journal of virology, 页码:2787-2796 , 文章类型: Article,,卷期:2012年86-5]
- Endogenous retroviruses constitute a significant genomic fraction in all mammalian species. Typically they are evolutionarily old and fixed in the host species population. Here we report on a novel endogenous gammaretrov...
- Natural Occurrence and Characterization of Two Internal Ribosome Entry Site Elements in a Novel Virus, Canine Picodicistrovirus, in the Picornavirus-Like Superfamily
[作者:Woo, PCY; Lau, SKP; Choi, GKY; Huang, Y; Teng, JLL; Tsoi, HW; Tse, H; Yeung, ML; Chan, KH; Jin, DY; Yuen, KY,期刊:Journal of virology, 页码:2797-2808 , 文章类型: Article,,卷期:2012年86-5]
- Dicistroviridae and Picornaviridae are two phylogenetically related families of positive-sense single-stranded RNA viruses in the picornavirus-like superfamily with similar gene contents but different genome organization...
- Espirito Santo Virus: a New Birnavirus That Replicates in Insect Cells
[作者:Vancini, R; Paredes, A; Ribeiro, M; Blackburn, K; Ferreira, D; Kononchik, JP; Hernandez, R; Brown, D,期刊:Journal of virology, 页码:2390-2399 , 文章类型: Article,,卷期:2012年86-5]
- Espirito Santo virus (ESV) is a newly discovered virus recovered as contamination in a sample of a virulent strain of dengue-2 virus (strain 44/2), which was recovered from a patient in the state of Espirito Santo, Brazi...
- Structure of an Antibody in Complex with Its Mucin Domain Linear Epitope That Is Protective against Ebola Virus
[作者:Olal, D; Kuehne, AI; Bale, S; Halfmann, P; Hashiguchi, T; Fusco, ML; Lee, JE; King, LB; Kawaoka, Y; Dye, JM; Saphire, EO,期刊:Journal of virology, 页码:2809-2816 , 文章类型: Article,,卷期:2012年86-5]
- Antibody 14G7 is protective against lethal Ebola virus challenge and recognizes a distinct linear epitope in the prominent mucin-like domain of the Ebola virus glycoprotein GP. The structure of 14G7 in complex with its l...
- Influenza A Virus Infection Results in a Robust, Antigen-Responsive, and Widely Disseminated Foxp3(+) Regulatory T Cell Response
[作者:Betts, RJ; Prabhu, N; Ho, AWS; Lew, FC; Hutchinson, PE; Rotzschke, O; Macary, PA; Kemeny, DM,期刊:Journal of virology, 页码:2817-2825 , 文章类型: Article,,卷期:2012年86-5]
- Foxp3(+) CD4(+) regulatory T cells (Tregs) represent a highly suppressive T cell subset with well-characterized immunosuppressive effects during immune homeostasis and chronic infections, although the role of these cells...
- Macrophage Internal HIV-1 Is Protected from Neutralizing Antibodies
[作者:Koppensteiner, H; Banning, C; Schneider, C; Hohenberg, H; Schindler, M,期刊:Journal of virology, 页码:2826-2836 , 文章类型: Article,,卷期:2012年86-5]
- In macrophages, HIV-1 accumulates in intracellular vesicles designated virus-containing compartments (VCCs). These might play an important role in the constitution of macrophages as viral reservoirs and allow HIV-1 to ev...
- Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus phi 6 from De Novo Initiation to Elongation
[作者:Wright, S; Poranen, MM; Bamford, DH; Stuart, DI; Grimes, JM,期刊:Journal of virology, 页码:2837-2849 , 文章类型: Article,,卷期:2012年86-5]
- RNA-dependent RNA polymerases (RdRps) are key to the replication of RNA viruses. A common divalent cation binding site, distinct from the positions of catalytic ions, has been identified in many viral RdRps. We have appl...
- CD4 T Cells Promote CD8 T Cell Immunity at the Priming and Effector Site during Viral Encephalitis
[作者:Phares, TW; Stohlman, SA; Hwang, M; Min, B; Hinton, DR; Bergmann, CC,期刊:Journal of virology, 页码:2416-2427 , 文章类型: Article,,卷期:2012年86-5]
- CD4 T cell activation during peripheral infections not only is essential in inducing protective CD8 T cell memory but also promotes CD8 T cell function and survival. However, the contributions of CD4 T cell help to antiv...
- Fluorescently Tagged pUL47 of Marek's Disease Virus Reveals Differential Tissue Expression of the Tegument Protein In Vivo
[作者:Jarosinski, KW; Arndt, S; Kaufer, BB; Osterrieder, N,期刊:Journal of virology, 页码:2428-2436 , 文章类型: Article,,卷期:2012年86-5]
- Marek's disease virus (MDV), a lymphotropic alphaherpesvirus, causes Marek's disease (MD) in chickens. MD is characterized by neurological signs, chronic wasting, and T cell lymphomas that predominate in the visceral org...
- Molecular Signatures Associated with Mx1-Mediated Resistance to Highly Pathogenic Influenza Virus Infection: Mechanisms of Survival
[作者:Cilloniz, C; Pantin-Jackwood, MJ; Ni, C; Carter, VS; Korth, MJ; Swayne, DE; Tumpey, TM; Katze, MG,期刊:Journal of virology, 页码:2437-2446 , 文章类型: Article,,卷期:2012年86-5]
- Understanding the role of host factors during lethal influenza virus infection is critical to deciphering the events that determine the fate of the host. One such factor is encoded by the Mx1 gene, which confers resistan...
- DNA-Binding Activity of Adeno-Associated Virus Rep Is Required for Inverted Terminal Repeat-Dependent Complex Formation with Herpes Simplex Virus ICP8
[作者:Alex, M; Weger, S; Mietzsch, M; Slanina, H; Cathomen, T; Heilbronn, R,期刊:Journal of virology, 页码:2859-2863 , 文章类型: Article,,卷期:2012年86-5]
- Herpes simplex virus (HSV) helper functions for (AAV) replication comprise HSV ICP8 and helicase-primase UL5/UL52/UL8. Here we show that N-terminal amino acids of AAV Rep78 that contact the Rep-binding site within the AA...
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