- Stabilizing G-Quadruplex DNA by a Scissors-Shaped Binaphthyl Derivative through the Entangling Mode: Cooperation of Binaphthylene and the Ethoxy Chain
[作者：Zhang, H; Xiang, JF; Hu, HY; Li, L; Jin, X; Liu, Y; Li, PF; Tang, YL; Chen, CF,期刊：Biochemistry, 页码：10351-10353 , 文章类型： Article，,卷期：2010年49-49]
- A scissors-shaped binaphthyl derivative (NPA) has been found to stabilize the G-quadruplex by intertwisting the whole G-quadruplex with two long chains, through the cooperation of the two functional groups: binaphthylene...
- Selective Incorporation of Nitrile-Based Infrared Probes into Proteins via Cysteine Alkylation
[作者：Jo, H; Culik, RM; Korendovych, IV; DeGrado, WF; Gai, F,期刊：Biochemistry, 页码：10354-10356 , 文章类型： Article，,卷期：2010年49-49]
- The nitrile stretching vibration is increasingly used as a sensitive infrared probe of local protein environments. However, site-specific incorporation of a nitrile moiety into proteins is difficult. Here we show that va...
- Unique Properties of the Mtr4p-Poly(A) Complex Suggest a Role in Substrate Targeting
[作者：Bernstein, J; Ballin, JD; Patterson, DN; Wilson, GM; Toth, EA,期刊：Biochemistry, 页码：10357-10370 , 文章类型： Article，,卷期：2010年49-49]
- Mtr4p is a DEVH-box helicase required for 3'-end processing and degradation of various nuclear RNA substrates. In particular, Mtr4p is essential for the creation of 5.8S rRNA, U4 snRNA, and some snoRNAs and for the degra...
- Hydralazine Modifies A beta Fibril Formation and Prevents Modification by Lipids in Vitro
[作者：Maheshwari, M; Roberts, JK; DeSutter, B; Duong, KT; Tingling, J; Fawver, JN; Schall, HE; Kahle, M; Murray, IVJ,期刊：Biochemistry, 页码：10371-10380 , 文章类型： Article，,卷期：2010年49-49]
- Lipid oxidative damage and amyloid beta (A beta) misfolding contribute to Alzheimer's disease (AD) pathology. Thus, the prevention of oxidative damage and A beta misfolding are attractive targets for drug discovery. At p...
- Important Roles of Tyr43 at the Putative Heme Distal Side in the Oxygen Recognition and Stability of the Fe(II)-O-2 Complex of YddV, a Globin-Coupled Heme-Based Oxygen Sensor Diguanylate Cyclase
[作者：Kitanishi, K; Kobayashi, K; Kawamura, Y; Ishigami, I; Ogura, T; Nakajima, K; Igarashi, J; Tanaka, A; Shimizu, T,期刊：Biochemistry, 页码：10381-10393 , 文章类型： Article，,卷期：2010年49-49]
- YddV from Escherichia coli (Ec) is a novel globin-coupled heme-based oxygen sensor protein displaying diguanylate cyclase activity in response to oxygen availability. In this study, we quantified the turnover numbers of ...
- Heme Pocket Structural Properties of a Bacterial Truncated Hemoglobin from Thermobifida fusca
[作者：Droghetti, E; Nicoletti, FP; Bonamore, A; Boechi, L; Manez, PA; Estrin, DA; Boffi, A; Smulevich, G; Feis, A,期刊：Biochemistry, 页码：10394-10402 , 文章类型： Article，,卷期：2010年49-49]
- An acidic surface variant (ASV) of the "truncated" hemoglobin from Thermobifida fusca was designed with the aim of creating a versatile globin scaffold endowed with thermostability and a high level of recombinant express...
- Screening of Selective Inhibitors of 1 alpha,25-Dihydroxyvitamin D-3 24-Hydroxylase Using Recombinant Human Enzyme Expressed in Escherichia coli
[作者：Zhu, JG; Barycki, R; Chiellini, G; DeLuca, HF,期刊：Biochemistry, 页码：10403-10411 , 文章类型： Article，,卷期：2010年49-49]
- High-level heterologous expression of human 1 alpha,25-dihydroxyvitamin D-3 24-hydroxylase (CYP24A1) in Escherichia coli was attained via a fusion construct by appending the mature CYP24A1 without the leader sequence to ...
- Characterization of Nicotinamidases: Steady State Kinetic Parameters, Classwide Inhibition by Nicotinaldehydes, and Catalytic Mechanism
[作者：French, JB; Cen, YN; Vrablik, TL; Xu, P; Allen, E; Hanna-Rose, W; Sauve, AA,期刊：Biochemistry, 页码：10421-10439 , 文章类型： Article，,卷期：2010年49-49]
- Nicotinamidases are metabolic enzymes that hydrolyze nicotinamide to nicotinic acid. These enzymes are widely distributed across biology, with examples found encoded in the genomes of Mycobacteria, Archaea, Eubacteria, P...
- Binding of the Hemopressin Peptide to the Cannabinoid CB1 Receptor: Structural Insights
[作者：Scrima, M; Di Marino, S; Grimaldi, M; Mastrogiacomo, A; Novellino, E; Bifulco, M; D'Ursi, AM,期刊：Biochemistry, 页码：10449-10457 , 文章类型： Article，,卷期：2010年49-49]
- Hemopressin, a bioactive nonapeptide derived from the alpha 1 chain of hemoglobin, was recently shown to possess selective antagonist activity at the cannabinoid CBI receptor [Heimann, A. S., et al. (2007) Proc. Natl. Ac...
- Insights into Nucleotide Recognition by Cell Division Protein FtsZ from a mant-GTP Competition Assay and Molecular Dynamics
[作者：Schaffner-Barbero, C; Gil-Redondo, R; Ruiz-Avila, LB; Huecas, S; Lappchen, T; den Blaauwen, T; Diaz, JF; Morreale, A; Andreu, JM,期刊：Biochemistry, 页码：10458-10472 , 文章类型： Article，,卷期：2010年49-49]
- Essential cell division protein FtsZ forms the bacterial cytokinetic ring and is a target for new antibiotics. FtsZ monomers bind GTP and assemble into filaments. Hydrolysis to GDP at the association interface between mo...
- Interaction of Human beta-Defensin 2 (HBD2) with Glycosaminoglycans
[作者：Seo, ES; Blaum, BS; Vargues, T; De Cecco, M; Deakin, JA; Lyon, M; Barran, PE; Campopiano, DJ; Uhrin, D,期刊：Biochemistry, 页码：10486-10495 , 文章类型： Article，,卷期：2010年49-49]
- Human beta-defensin 2 (HBD2) is a member of the defensin family of antimicrobial peptides that plays important roles in the innate and adaptive immune system of both vertebrates and invertebrates. In addition to their di...
- Mechanism of Inactivation of Escherichia coli Aspartate Aminotransferase by (S)-4-Amino-4,5-dihydro-2-furancarboxylic Acid
[作者：Liu, DL; Pozharski, E; Fu, MM; Silverman, RB; Ringe, D,期刊：Biochemistry, 页码：10507-10515 , 文章类型： Article，,卷期：2010年49-49]
- As a potential drug to treat neurological diseases, the mechanism-based inhibitor (S)-4-amino-4,5-dihydro-2-furancarboxylic acid (S-ADFA) has been found to inhibit the gamma-aminobutyric acid aminotransferase (GABA-AT) r...
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