- A Q63E Rhodobacter sphaeroides AppA BLUF Domain Mutant Is Locked in a Pseudo-Light-Excited Signaling State
[作者:Dragnea, V; Arunkumar, AI; Lee, CW; Giedroc, DP; Bauer, CE,期刊:Biochemistry, 页码:10682-10690 , 文章类型: Article,,卷期:2010年49-50]
- The AppA BLUF photoreceptor from Rhodobacter sphaeroides contains a conserved key residue, Gln63, that is thought to undergo a shift in hydrogen-bonding interactions when a bound flavin is light excited. In this study we...
- A Study of the Evolution of Inverted-Topology Repeats from LeuT-Fold Transporters Using AlignMe
[作者:Khafizov, K; Staritzbichler, R; Stamm, M; Forrest, LR,期刊:Biochemistry, 页码:10702-10713 , 文章类型: Article,,卷期:2010年49-50]
- X-ray crystal structures have revealed that numerous secondary transporter proteins originally categorized into different sequence families share similar structures, namely, the LeuT fold. The core of this fold consists ...
- Domain Architecture of the DRpp29 Protein and Its interaction with the RNA Subunit of Dictyostelium discoideum RNase P
[作者:Stamatopoulou, V; Toumpeki, C; Tzakos, A; Vourekas, A; Drainas, D,期刊:Biochemistry, 页码:10714-10727 , 文章类型: Article,,卷期:2010年49-50]
- Dictyostelium discoideum nuclear RNase P is a ribonucleoprotein complex that displays similarities with its counterparts from higher eukaryotes such as the human enzyme, but at the same time it retains distinctive charac...
- HDAC6 and Ubp-M BUZ Domains Recognize Specific C-Terminal Sequences of Proteins
[作者:Hard, RL; Liu, JX; Shen, JA; Zhou, P; Pei, DH,期刊:Biochemistry, 页码:10737-10746 , 文章类型: Article,,卷期:2010年49-50]
- The BUZ/Znf-UBP domain is a protein module found in the cytoplasmic deacetylase HDAC6, E3 ubiquitin ligase BRAP2/IMP, and a subfamily of ubiquitin-specific proteases. Although several BUZ domains have been shown to bind ...
- Seipin Is a Discrete Homooligomer
[作者:Binns, D; Lee, S; Hilton, CL; Jiang, QX; Goodman, JM,期刊:Biochemistry, 页码:10747-10755 , 文章类型: Article,,卷期:2010年49-50]
- Seipin is a transmembrane protein that resides in the endoplasmic reticulum and concentrates at junctions between the ER and cytosolic lipid droplets. Mutations in the human seipin gene, including the missense mutation A...
- Molecular Level Interaction of the Human Acidic Fibroblast Growth Factor with the Antiangiogenic Agent, Inositol Hexaphosphate
[作者:Kumar, SM; Wang, HM; Mohan, SK; Chou, RH; Yu, C,期刊:Biochemistry, 页码:10756-10764 , 文章类型: Article,,卷期:2010年49-50]
- Acidic fibroblast growth factor (FGF1) regulates a wide array of important biological phenomena such as angiogenesis, cell differentiation, tumor growth, and neurogenesis. Generally, FGFs are known for their strong affin...
- Novel Hydrophobic Standards for Membrane Protein Molecular Weight Determinations via Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis
[作者:Rath, A; Nadeau, VG; Poulsen, BE; Ng, DP; Deber, CM,期刊:Biochemistry, 页码:10589-10591 , 文章类型: Article,,卷期:2010年49-50]
- Sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) is a universally employed technique that separates proteins on the basis of molecular weight (MW). However, membrane proteins are known to size anomalo...
- The Proline/Arginine-Rich Domain Is a Major Determinant of Dynamin Self-Activation
[作者:Barylko, B; Wang, L; Binns, DD; Ross, JA; Tassin, TC; Collins, KA; Jameson, DM; Albanesi, JP,期刊:Biochemistry, 页码:10592-10594 , 文章类型: Article,,卷期:2010年49-50]
- Dynamins induce membrane vesiculation during endocytosis and Golgi budding in a process that requires assembly-dependent GTPase activation. Brain-specific dynamin 1 has a weaker propensity to self-assemble and self-activ...
- Limiting an Antimicrobial Peptide to the Lipid-Water Interface Enhances Its Bacterial Membrane Selectivity: A Case Study of MSI-367
[作者:Thennarasu, S; Huang, R; Lee, DK; Yang, P; Maloy, L; Chen, Z; Ramamoorthy, A,期刊:Biochemistry, 页码:10595-10605 , 文章类型: Article,,卷期:2010年49-50]
- In a minimalist design approach, a synthetic peptide MSI-367 [(KFAKKFA)(3)-NH2] was designed and synthesized with the objective of generating cell-selective nonlytic peptides, which have a significant bearing on cell tar...
- An Investigation of the Distal Histidyl Hydrogen Bonds in Oxyhemoglobin: Effects of Temperature, pH, and Inositol Hexaphosphate
[作者:Yuan, Y; Simplaceanu, V; Ho, NT; Ho, C,期刊:Biochemistry, 页码:10606-10615 , 文章类型: Article,,卷期:2010年49-50]
- On the basis of X-ray crystal structures and electron paramagnetic resonance (EPR) measurements, it has been inferred that the O-2 binding to hemoglobin is stabilized by the hydrogen bonds between the oxygen ligands and ...
- Oxidation of Histidine Residues in Copper-Zinc Superoxide Dismutase by Bicarbonate-Stimulated Peroxidase and Thiol Oxidase Activities: Pulse EPR and NMR Studies
[作者:Chandran, K; McCracken, J; Peterson, FC; Antholine, WE; Volkman, BF; Kalyanaraman, B,期刊:Biochemistry, 页码:10616-10622 , 文章类型: Article,,卷期:2010年49-50]
- In this work, we investigated the oxidative modification of histidine residues induced by peroxidase and thiol oxidase activities of bovine copper-zinc superoxide dismutase (Cu-ZnSOD) using NMR and pulse EPR spectroscopy...
- Cytochrome P450 from Photobacterium profundum SS9, a Piezophilic Bacterium, Exhibits a Tightened Control of Water Access to the Active Site
[作者:Sineva, EV; Davydov, DR,期刊:Biochemistry, 页码:10636-10646 , 文章类型: Article,,卷期:2010年49-50]
- We report cloning, expression in Escherichia call, and purification of cytochrome P450 from a deep-sea bacterium Photobacteriwn profundum strain SS9 (P450-SS9). The enzyme, which is predominately high spin (86%) in the a...
|