个性化文献订阅>文章检索

文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共20条记录   Physical Trapping of HIV-1 Synaptic Complex by Different Structural Classes of Integrase Strand Transfer Inhibitors [作者：Pandey, KK; Bera, S; Vora, AC; Grandgenett, DP,期刊：Biochemistry, 页码：8376-8387 , 文章类型： Article，,卷期：2010年49-38] Raltegravir is an FDA approved inhibitor directed against human immunodeficiency virus type 1 (HIV-1) integrase (IN). in this study, we investigated the mechanisms associated with multiple strand transfer inhibitors capa... A Novel Disulfide Pattern in Laminin-Type Epidermal Growth Factor-like (LE) Modules of Laminin beta 1 and gamma 1 Chains [作者：Kalkhof, S; Witte, K; Ihling, CH; Muller, MQ; Keller, MV; Haehn, S; Smyth, N; Paulsson, M; Sinz, A,期刊：Biochemistry, 页码：8359-8366 , 文章类型： Article，,卷期：2010年49-38] In-depth mass spectrometric analysis of disulfide bond patterns in recombinant mouse laminin beta 1 and gamma 1 chain N-terminal fragments comprising the laminin N-terminal (LN) domain and the first four laminin epiderma... STPR, a 23-Amino Acid Tandem Repeat Domain, Found in the Human Function-Unknown Protein ZNF821 [作者：Nonaka, Y; Muto, H; Aizawa, T; Okabe, E; Myoba, S; Yokoyama, T; Saito, S; Tatami, F; Kumaki, Y; Kamiya, M; Kikukawa, T; Mizuguchi, M; Takiya, S; Kinjo, M; Demura, M; Kawano, K,期刊：Biochemistry, 页码：8367-8375 , 文章类型： Article，,卷期：2010年49-38] The STPR motif is composed of 23-amino acid repeats aligned contiguously. STPR was originally reported as the DNA-binding domain of the silkworm protein FMBP-1. ZNF821, the human protein that contains the STPR domain, is... Characterization of the N-Acetyl-alpha-D-glucosaminyl L-Malate Synthase and Deacetylase Functions for Bacillithiol Biosynthesis in Bacillus anthracis [作者：Parsonage, D; Newton, GL; Holder, RC; Wallace, BD; Paige, C; Hamilton, CJ; Dos Santos, PC; Redinbo, MR; Reid, SD; Claiborne, A,期刊：Biochemistry, 页码：8398-8414 , 文章类型： Article，,卷期：2010年49-38] Bacillithiol (Cys-GlcN-malate, BSH) has recently been identified as a novel low-molecular weight thiol in Bacillus anthracis, Staphylococcus aureus, and several other Gram-positive bacteria lacking glutathione and myc... Selective Targeting of G-Quadruplex Using Furan-Based Cyclic Homooligopeptides: Effect on c-MYC Expression [作者：Agarwal, T; Roy, S; Chakraborty, TK; Maiti, S,期刊：Biochemistry, 页码：8388-8397 , 文章类型： Article，,卷期：2010年49-38] Quadruplex-specific molecules can serve as suitable drugs in cancer therapy. We have synthesized a pair of furan-based cyclic homooligopeptides, ligand 1 and ligand 2, to specifically target G-quadruplexes. We have shown... Generation of a Manganese Specific Restriction Endonuclease with Nicking Activity [作者：Vasu, K; Saravanan, M; Rajendra, BVRN; Nagaraja, V,期刊：Biochemistry, 页码：8425-8433 , 文章类型： Article，,卷期：2010年49-38] A typical feature of type II restriction endonucleases (REases) is their obligate sequence specificity and requirement for Mg2+ during catalysis. R.KpnI is an exception. Unlike most other type II REases, the active site ... In Vitro Bypass of the Major Malondialdehyde- and Base Propenal-Derived DNA Adduct by Human Y-family DNA Polymerases kappa, iota, and Rev1 [作者：Maddukuri, L; Eoff, RL; Choi, JY; Rizzo, CJ; Guengerich, FP; Marnett, LJ,期刊：Biochemistry, 页码：8415-8424 , 文章类型： Article，,卷期：2010年49-38] 3-(2'-Deoxy-beta-D-erythro-pentofuranosyl)pyrimido-[1,2-alpha]purin-10(3H)-one (M(1)dG) is the major adduct derived from the reaction of DNA with the lipid peroxidation product malondialdehyde and the DNA peroxidation pr... Comparative Kinetics of Cofactor Association and Dissociation for the Human and Trypanosomal S-Adenosylhomocysteine Hydrolases. 3. Role of Lysyl and Tyrosyl Residues of the C-Terminal Extension [作者：Cai, SM; Fang, JW; Li, QS; Borchard, RT; Kuczera, K; Middaugh, CR; Schowen, RL,期刊：Biochemistry, 页码：8434-8441 , 文章类型： Article，,卷期：2010年49-38] On the basis of the available X-ray structures of S-adenosylhomocysteine hydrolases (SAHHs), free energy simulations employing the MM-GBSA approach were applied to predict residues important to the differential cofactor ... Structure and RNA Interactions of the Plant MicroRNA Processing-Associated Protein HYL1 [作者：Rasia, RM; Mateos, J; Bologna, NG; Burdisso, P; Imbert, L; Palatnik, JF; Boisbouvier, J,期刊：Biochemistry, 页码：8237-8239 , 文章类型： Article，,卷期：2010年49-38] HYL1 is a double-stranded RNA binding protein involved in micro RNA processing in plants. HYL1 enhances the efficiency and precision of the RNase III protein DCL1 and participates in microRNA strand selection. In this wo... Oncogenic CARD11 Mutations Induce Hyperactive Signaling by Disrupting Autoinhibition by the PKC-Responsive Inhibitory Domain [作者：Lamason, RL; McCully, RR; Lew, SM; Pomerantz, JL,期刊：Biochemistry, 页码：8240-8250 , 文章类型： Article，,卷期：2010年49-38] The regulated activation of NF-kappa B by antigen receptor signaling is required for normal B and T lymphocyte activation during the adaptive immune response. Dysregulated NF-kappa B activation is associated with several... Competitive and Noncompetitive Binding of eIF4B, eIF4A, and the Poly(A) Binding Protein to Wheat Translation Initiation Factor eIFiso4G [作者：Cheng, SJ; Gallie, DR,期刊：Biochemistry, 页码：8251-8265 , 文章类型： Article，,卷期：2010年49-38] Eukaryotic translation initiation factor 4G (eIF4G) functions to organize the assembly of initiation factors required for the recruitment of a 40S ribosomal subunit to an mRNA and for interacting with the poly(A) binding... Characterization of the Interaction of beta-Amyloid with Transthyretin Monomers and Tetramers [作者：Du, JL; Murphy, RM,期刊：Biochemistry, 页码：8276-8289 , 文章类型： Article，,卷期：2010年49-38] beta-Amyloid (A beta) is the main protein component of the amyloid plaques associated with Alzheimer's disease. Transthyretin (TTR) is a homotetramer that circulates in both blood and cerebrospinal fluid. Wild-type (wt) ... Binding of the Dimeric Deinococcus radiodurans Single-Stranded DNA Binding Protein to Single-Stranded DNA [作者：Kozlov, AG; Eggington, JM; Cox, MM; Lohman, TM,期刊：Biochemistry, 页码：8266-8275 , 文章类型： Article，,卷期：2010年49-38] Deinococcus radiodurans single-stranded (ss) DNA binding protein (DrSSB) originates from a radiation-resistant bacterium and participates in DNA recombination, replication, and repair. Although it functions as a homodime... DsrJ, an Essential Part of the DsrMKJOP Transmembrane Complex in the Purple Sulfur Bacterium Allochromatium vinosum, Is an Unusual Triheme Cytochrome c [作者：Grein, F; Venceslau, SS; Schneider, L; Hildebrandt, P; Todorovic, S; Pereira, IAC; Dahl, C,期刊：Biochemistry, 页码：8290-8299 , 文章类型： Article，,卷期：2010年49-38] The DsrMKJOP transmembrane complex has a most important function in dissimilatory sulfur metabolism, not only in many sulfur-oxidizing organisms but also in sulfate-reducing prokaryotes. Here, we focused on an individual... The BCL-2 5 ' Untranslated Region Contains an RNA G-Quadruplex-Forming Motif That Modulates Protein Expression [作者：Shahid, R; Bugaut, A; Balasubramanian, S,期刊：Biochemistry, 页码：8300-8306 , 文章类型： Article，,卷期：2010年49-38] The BCL-2 gene encodes a 25 kDa membrane protein that plays critical roles in the control of apoptosis. The regulation of BCL-2 gene expression is highly complex and occurs both transcriptionally and posttranscriptionall... Activation and Specificity of Human Caspase-10 [作者：Wachmann, K; Pop, C; van Raam, BJ; Drag, M; Mace, PD; Snipas, SJ; Zmasek, C; Schwarzenbacher, R; Salvesen, GS; Riedl, SJ,期刊：Biochemistry, 页码：8307-8315 , 文章类型： Article，,卷期：2010年49-38] Two apical caspases, caspase-8 and -10, are involved in the extrinsic death receptor pathway in humans, but it is mainly caspase-8 in its apoptotic and nonapoptotic functions that has been an intense research focus. In t...