- Myogenin and Class II HDACs Control Neurogenic Muscle Atrophy by Inducing E3 Ubiquitin Ligases
[作者：Moresi, V; Williams, AH; Meadows, E; Flynn, JM; Potthoff, MJ; McAnally, J; Shelton, JM; Backs, J; Klein, WH; Richardson, JA; Bassel-Duby, R; Olson, EN,期刊：Cell, 页码：35-45 , 文章类型： Article，,卷期：2010年143-1]
- Maintenance of skeletal muscle structure and function requires innervation by motor neurons, such that denervation causes muscle atrophy. We show that myogenin, an essential regulator of muscle development, controls neur...
- Long Noncoding RNAs with Enhancer-like Function in Human Cells
[作者：Orom, UA; Derrien, T; Beringer, M; Gumireddy, K; Gardini, A; Bussotti, G; Lai, F; Zytnicki, M; Notredame, C; Huang, QH; Guigo, R; Shiekhattar, R,期刊：Cell, 页码：46-58 , 文章类型： Article，,卷期：2010年143-1]
- While the long noncoding RNAs (ncRNAs) constitute a large portion of the mammalian transcriptome, their biological functions has remained elusive. A few long ncRNAs that have been studied in any detail silence gene expre...
- Molecular Basis of RNA Polymerase III Transcription Repression by Maf1
[作者：Vannini, A; Ringel, R; Kusser, AG; Berninghausen, O; Kassavetis, GA; Cramer, P,期刊：Cell, 页码：59-70 , 文章类型： Article，,卷期：2010年143-1]
- RNA polymerase III (Pol III) transcribes short RNAs required for cell growth. Under stress conditions, the conserved protein Maf1 rapidly represses Pol III transcription. We report the crystal structure of Maf1 and cryo-...
- Identification of Aneuploidy-Tolerating Mutations
[作者：Torres, EM; Dephoure, N; Panneerselvam, A; Tucker, CM; Whittaker, CA; Gygi, SP; Dunham, MJ; Amon, A,期刊：Cell, 页码：71-83 , 文章类型： Article，,卷期：2010年143-1]
- Aneuploidy causes a proliferative disadvantage in all normal cells analyzed to date, yet this condition is associated with a disease characterized by unabated proliferative potential, cancer. The mechanisms that allow ca...
- Store-Independent Activation of Orai1 by SPCA2 in Mammary Tumors
[作者：Feng, MY; Grice, DM; Faddy, HM; Nguyen, N; Leitch, S; Wang, YY; Muend, S; Kenny, PA; Sukumar, S; Roberts-Thomson, SJ; Monteith, GR; Rao, R,期刊：Cell, 页码：84-98 , 文章类型： Article，,卷期：2010年143-1]
- Ca2+ is an essential and ubiquitous second messenger. Changes in cytosolic Ca2+ trigger events critical for tumorigenesis, such as cellular motility, proliferation, and apoptosis. Weshow that an isoform of Secretory Path...
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