- Adenosine Receptor Modeling: What Does the A(2A) Crystal Structure Tell Us?
[作者:Dal Ben, D; Lambertucci, C; Marucci, G; Volpini, R; Cristalli, G,期刊:Current Topics in Medicinal Chemistry, 页码:993-1018 , 文章类型: Review,,卷期:2010年10-10]
- For a long time, there have been no experimentally determined structural data for any adenosine receptor (AR) and the only approach available for making structure/function correlations about these proteins has been homol...
- Adenosine Receptor Ligands in Clinical Trials
[作者:Rizzolio, F; La Montagna, R; Tuccinardi, T; Russo, G; Caputi, M; Giordano, A,期刊:Current Topics in Medicinal Chemistry, 页码:1036-1045 , 文章类型: Review,,卷期:2010年10-10]
- Adenosine and its receptors play different roles in normal and patho-physiological conditions. For these reasons, many laboratories have focused their attention on dissecting the molecular pathway underlying the mechanis...
- A(3) Receptor Ligands: Past, Present and Future Trends
[作者:Taliani, S; Pugliesi, I; Bellandi, M; La Motta, C; Da Settimo, F,期刊:Current Topics in Medicinal Chemistry, 页码:942-975 , 文章类型: Review,,卷期:2010年10-10]
- The A(3) adenosine receptors (A(3) ARs), belonging to the adenosine receptor family of G-protein-coupled receptors (GPCRs), are ubiquitously expressed in a wide variety of tissues in human body, with high levels in perip...
- Allosteric Modulators for Adenosine Receptors: An Alternative to the Orthosteric Ligands
[作者:La Motta, C; Sartini, S; Morelli, M; Taliani, S; Da Settimo, F,期刊:Current Topics in Medicinal Chemistry, 页码:976-992 , 文章类型: Review,,卷期:2010年10-10]
- Adenosine is a ubiquitous homeostatic substance which exerts its action by triggering four different cell membrane G protein-coupled receptors, classified as A(1), A(2A), A(2B), and A(3). As they are widely distributed a...
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