- Impact of novel oncolytic virus HF10 on cellular components of the tumor microenviroment in patients with recurrent breast cancer
[作者：Sahin, TT; Kasuya, H; Nomura, N; Shikano, T; Yamamura, K; Gewen, T; Kanzaki, A; Fujii, T; Sugae, T; Imai, T; Nomoto, S; Takeda, S; Sugimoto, H; Kikumori, T; Kodera, Y; Nishiyama, Y; Nakao, A,期刊：Cancer gene therapy, 页码：229-237 , 文章类型： Article，,卷期：2012年19-4]
- Oncolytic viruses are a promising method of cancer therapy, even for advanced malignancies. HF10, a spontaneously mutated herpes simplex type 1, is a potent oncolytic agent. The interaction of oncolytic herpes viruses wi...
- Expressing human interleukin-15 from oncolytic vesicular stomatitis virus improves survival in a murine metastatic colon adenocarcinoma model through the enhancement of anti-tumor immunity
[作者：Stephenson, KB; Barra, NG; Davies, E; Ashkar, AA; Lichty, BD,期刊：Cancer gene therapy, 页码：238-246 , 文章类型： Article，,卷期：2012年19-4]
- In this study, we sought to enhance the potency of an oncolytic virus, vesicular stomatitis virus (VSV), by inserting a transgene encoding a highly secreted version of human interleukin-15 (IL-15). IL-15 has shown promis...
- A novel conditionally replicating adenoviral vector with dual expression of IL-24 and arresten inserted in E1 and the region between E4 and fiber for improved melanoma therapy
[作者：Chai, L; Liu, S; Mao, Q; Wang, D; Li, X; Zheng, X; Xia, H,期刊：Cancer gene therapy, 页码：247-254 , 文章类型： Article，,卷期：2012年19-4]
- Although the combination of gene therapy and virotherapy for cancer therapy has obtained some encouraging results in vitro and in vivo over the past few years, some improvements of the vectors are still urgently needed t...
- Hypoxia imaging predicts success of hypoxia-induced cytosine deaminase/5-fluorocytosine gene therapy in a murine lung tumor model
[作者：Lee, BF; Lee, CH; Chiu, NT; Hsia, CC; Shen, LH; Shiau, AL,期刊：Cancer gene therapy, 页码：255-262 , 文章类型： Article，,卷期：2012年19-4]
- Tc-99m-HL91 is a hypoxia imaging biomarker. The aim of this study was to investigate the value of Tc-99m-HL91 imaging for hypoxia-induced cytosine deaminase (CD)/5-fluorocytosine (5-FC) gene therapy in a murine lung tumo...
- Complementary treatment of siTERT for improving the antitumor effect of TERT-specific I-131 therapy
[作者：Kim, S; Youn, H; Song, MG; Kang, JH; Chung, HK; Lee, DS; Chung, JK,期刊：Cancer gene therapy, 页码：263-270 , 文章类型： Article，,卷期：2012年19-4]
- Sodium iodide symporter (NIS)-based radionuclide therapy provides an effective means of treating malignant tumors. However, it is sometimes inadequate because of limited effects on radio-resistant tumors, and thus, combi...
- Adenovirus-mediated Aurora A shRNA driven by stathmin promoter suppressed tumor growth and enhanced paclitaxel chemotherapy sensitivity in human breast carcinoma cells
[作者：Long, M; Yin, G; Liu, L; Lin, F; Wang, X; Ren, J; Wei, J; Dong, K; Zhang, H,期刊：Cancer gene therapy, 页码：271-281 , 文章类型： Article，,卷期：2012年19-4]
- Aurora A has multiple key functions in tumor initiation and progression and is overexpressed in many cancers. Several ongoing clinical trials are assessing the unique therapeutic potential of Aurora-based targeted therap...
- Antitumor efficacy of oncolytic herpes simplex virus adsorbed onto antigen-specific lymphocytes
[作者：Kanzaki, A; Kasuya, H; Yamamura, K; Sahin, TT; Nomura, N; Shikano, T; Shirota, T; Tan, G; Fukuda, S; Misawa, M; Nishikawa, Y; Yamada, S; Fujii, T; Sugimoto, H; Nomoto, S; Takeda, S; Kodera, Y; Nakao, A,期刊：Cancer gene therapy, 页码：292-298 , 文章类型： Article，,卷期：2012年19-4]
- Although several studies have reported that locally administering oncolytic viruses effectively targets malignancies, the efficacy of systemically administered oncolytic viruses is restricted. Recently, however, it was r...
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