- Solution Structure of Mycobacterium tuberculosis NmtR in the Apo State: Insights into Ni(II)-Mediated Allostery
[作者:Lee, CW; Chakravorty, DK; Chang, FMJ; Reyes-Caballero, H; Ye, YZ; Merz, KM; Giedroc, DP,期刊:Biochemistry, 页码:2619-2629 , 文章类型: Article,,卷期:2012年51-12]
- Mycobacterium tuberculosis is an obligate human respiratory pathogen that encodes approximately 10 arsenic repressor (ArsR) family regulatory proteins that allow the organism to respond to a wide range of changes in its ...
- Schiff Base Protonation Changes in Siberian Hamster Ultraviolet Cone Pigment Photointermediates
[作者:Mooney, VL; Szundi, I; Lewis, JW; Yan, ECY; Kliger, DS,期刊:Biochemistry, 页码:2630-2637 , 文章类型: Article,,卷期:2012年51-12]
- Molecular structure and function studies of vertebrate ultraviolet (UV) cone visual pigments are needed to understand the molecular evolution of these photoreceptors, which uniquely contain unprotonated Schiff base linka...
- Identification of an Ubinuclein 1 Region Required for Stability and Function of the Human HIRA/UBN1/CABIN1/ASF1a Histone H3.3 Chaperone Complex
[作者:Tang, Y; Puri, A; Ricketts, MD; Rai, TS; Hoffmann, J; Hoi, E; Adams, PD; Schultz, DC; Marmorstein, R,期刊:Biochemistry, 页码:2366-2377 , 文章类型: Article,,卷期:2012年51-12]
- The mammalian HIRA/UBN1/CABIN1/ASF1a (HUCA) histone chaperone complex deposits the histone H3 variant H3.3 into chromatin and is linked to gene activation, repression, and chromatin assembly in diverse cell contexts. We ...
- Solution Structure of the Dickerson DNA Dodecamer Containing a Single Ribonucleotide
[作者:DeRose, EF; Perera, L; Murray, MS; Kunkel, TA; London, RE,期刊:Biochemistry, 页码:2407-2416 , 文章类型: Article,,卷期:2012年51-12]
- Ribonucleotides are frequently incorporated into DNA during replication. They are recognized and processed by several cellular enzymes, and their continued presence in the yeast nuclear genome results in replicative stre...
- Peptidyl 3-Hydroxyproline Binding Properties of Type I Collagen Suggest a Function in Fibril Supramolecular Assembly
[作者:Hudson, DM; Kim, LS; Weis, M; Cohn, DH; Eyre, DR,期刊:Biochemistry, 页码:2417-2424 , 文章类型: Article,,卷期:2012年51-12]
- Proline residues in collagens are extensively hydroxylated post-translationally. A rare form of this modification, (3S,2S)-L-hydroxyproline (3Hyp), remains without a clear function. Disruption of the enzyme complex respo...
- Bupropion Binds to Two Sites in the Torpedo Nicotinic Acetylcholine Receptor Transmembrane Domain: A Photoaffinity Labeling Study with the Bupropion Analogue [I-125]-SADU-3-72
[作者:Pandhare, A; Hamouda, AK; Staggs, B; Aggarwal, S; Duddempudi, PK; Lever, JR; Lapinsky, DJ; Jansen, M; Cohen, JB; Blanton, MP,期刊:Biochemistry, 页码:2425-2435 , 文章类型: Article,,卷期:2012年51-12]
- Bupropion, a clinically used antidepressant and smoking-cessation drug, acts as a noncompetitive antagonist of nicotinic acetylcholine receptors (nAChRs). To identify its binding site(s) in nAChRs, we developed a photore...
- Differential Binding between PatS C-Terminal Peptide Fragments and HetR from Anabaena sp PCC 7120
[作者:Feldmann, EA; Ni, SS; Sahu, ID; Mishler, CH; Leyengood, JD; Kushnir, Y; McCarrick, RM; Lorigan, GA; Tolbert, BS; Callahan, SM; Kennedy, MA,期刊:Biochemistry, 页码:2436-2442 , 文章类型: Article,,卷期:2012年51-12]
- Heterocyst differentiation in the filamentous cyanobacterium Anabaena sp. strain PCC 7120 occurs at regular intervals under nitrogen starvation and is regulated by a host of signaling molecules responsive to availability...
- A Variable Light Domain Fluorogen Activating Protein Homodimerizes To Activate Dimethylindole Red
[作者:Senutovitch, N; Stanfield, RL; Bhattacharyya, S; Rule, GS; Wilson, IA; Armitage, BA; Waggoner, AS; Berget, PB,期刊:Biochemistry, 页码:2471-2485 , 文章类型: Article,,卷期:2012年51-12]
- Novel fluorescent tools such as green fluorescent protein analogues and fluorogen activating proteins (FAPs) are useful in biological imaging for tracking protein dynamics in real time with a low fluorescence background....
- Toxoplasma gondii Profilin Acts Primarily To Sequester G-Actin While Formins Efficiently Nucleate Actin Filament Formation in Vitro
[作者:Skillman, KM; Daher, W; Ma, CI; Soldati-Favre, D; Sibley, LD,期刊:Biochemistry, 页码:2486-2495 , 文章类型: Article,,卷期:2012年51-12]
- Apicomplexan parasites employ gliding motility that depends on the polymerization of parasite actin filaments for host cell entry. Despite this requirement, parasite actin remains almost entirely unpolymerized at steady ...
- The Thermococcus kodakaraensis Tko CDC21-1 Intein Activates Its N-Terminal Splice Junction in the Absence of a Conserved Histidine by a Compensatory Mechanism
[作者:Tori, K; Cheriyan, M; Pedamallu, CS; Contreras, MA; Perler, FB,期刊:Biochemistry, 页码:2496-2505 , 文章类型: Article,,卷期:2012年51-12]
- Inteins and other self-catalytic enzymes, such as glycosylasparaginases and hedgehog precursors, initiate autocleavage by converting a peptide bond to a (thio)ester bond when Ser, Thr, or Cys undergoes an N-[S/O] acyl mi...
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