- Characterization of BshA, bacillithiol glycosyltransferase from Staphylococcus aureus and Bacillus subtilis
[作者:Upton, H; Newton, GL; Gushiken, M; Lo, K; Holden, D; Fahey, RC; Rawat, M,期刊:FEBS Letters, 页码:1004-1008 , 文章类型: Article,,卷期:2012年586-7]
- The first step during bacillithiol (BSH) biosynthesis involves the formation of N-acetylglucosaminylmalate from UDP-N-acetylglucosamine and L-malate and is catalyzed by a GT4 class glycosyltransferase enzyme (BshA). Reco...
- New phosphate binding sites in the crystal structure of Escherichia coli purine nucleoside phosphorylase complexed with phosphate and formycin A
[作者:Stefanic, Z; Narczyk, M; Mikleusevic, G; Wielgus-Kutrowska, B; Bzowska, A; Luic, M,期刊:FEBS Letters, 页码:967-971 , 文章类型: Article,,卷期:2012年586-7]
- Purine nucleoside phosphorylase (PNP) from Escherichia coli is a homohexamer that catalyses the phosphorolytic cleavage of the glycosidic bond of purine nucleosides. The first crystal structure of the ternary complex of ...
- Differential usage of NF-kappa B activating signals by IL-1 beta and TNF-alpha in pancreatic beta cells
[作者:Ortis, F; Miani, M; Colli, ML; Cunha, DA; Gurzov, EN; Allagnat, F; Chariot, A; Eizirik, DL,期刊:FEBS Letters, 页码:984-989 , 文章类型: Article,,卷期:2012年586-7]
- The cytokines interleukin (IL)-1 beta and tumor necrosis factor (TNF)-alpha induce beta-cell death in type 1 diabetes via NF-kappa B activation. IL-1 beta induces a more marked NF-kappa B activation than TNF-alpha, with ...
- The bacterial-type phosphoenolpyruvate carboxylase isozyme from developing castor oil seeds is subject to in vivo regulatory phosphorylation at serine-451
[作者:Dalziel, KJ; O'Leary, B; Brikis, C; Rao, SK; She, YM; Cyr, T; Plaxton, WC,期刊:FEBS Letters, 页码:1049-1054 , 文章类型: Article,,卷期:2012年586-7]
- Phosphoenolpyruvate carboxylase (PEPC) is a tightly controlled anaplerotic enzyme situated at a pivotal branch point of plant carbohydrate-metabolism. In developing castor oil seeds (COS) a novel allosterically-densensit...
- The inhibitory effect of miRNA-1 on ET-1 gene expression
[作者:Li, D; He, B; Zhang, H; Shan, SF; Liang, Q; Yuan, WJ; Ren, AJ,期刊:FEBS Letters, 页码:1014-1021 , 文章类型: Article,,卷期:2012年586-7]
- There is a close correlation between endothelin-1 (ET-1) and microRNA-1 (miRNA-1) expression in the heart, but whether ET-1 expression is regulated by miRNA-1 warrants further research. Our results revealed multiple clue...
- TLR-induced NF-kappa B activation regulates NLRP3 expression in murine macrophages
[作者:Qiao, Y; Wang, P; Qi, JN; Zhang, L; Gao, CJ,期刊:FEBS Letters, 页码:1022-1026 , 文章类型: Article,,卷期:2012年586-7]
- NLRP3 inflammasome plays a critical role in the activation of caspase-1 and maturation of IL-1 beta. However, the specific cis- and trans-regulatory elements that determine the extent of NLRP3 expression are not well def...
- Tumor suppressor RBM5 directly interacts with the DExD/H-box protein DHX15 and stimulates its helicase activity
[作者:Niu, ZY; Jin, WX; Zhang, LB; Li, XL,期刊:FEBS Letters, 页码:977-983 , 文章类型: Article,,卷期:2012年586-7]
- RNA binding motif protein 5 (RBM5) is a candidate tumor suppressor gene. Recent studies showed that RBM5 functions as an alternative splicing regulator of apoptosis-related genes. Here, we identify DHX15 and PRP19, two s...
- UGT75L6 and UGT94E5 mediate sequential glucosylation of crocetin to crocin in Gardenia jasminoides
[作者:Nagatoshi, M; Terasaka, K; Owaki, M; Sota, M; Inukai, T; Nagatsu, A; Mizukami, H,期刊:FEBS Letters, 页码:1055-1061 , 文章类型: Article,,卷期:2012年586-7]
- Crocin is an apocarotenoid glycosyl ester accumulating in fruits of Gardenia jasminoides and used as a food coloring and nutraceutical. For the first time, the two glucosyltransferases UGT75L6 and UGT94E5 that sequential...
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